대한한방내과학회지 (The Journal of Internal Korean Medicine)
- 제28권2호
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- Pages.321-332
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- 2007
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- 1226-9174(pISSN)
가미보아탕(加味保我湯) 및 수종(數種) 한방처방의 항암효과에 대한 연구
Anti-cancer Effects of Kamiboa-tang and some other Traditional Medical Prescriptions
초록
Objectives : Anticancer and immune-modulating effects of several Korean medical prescriptions including Yukgunja-tang, Bohwa-tang, Sogam-Won, and Kamiboa-tang were investigated. Methods : In vitro anti-cancer effects were measured by cytotoxicity MTT assay using SNU-1 gastric cancer cell lines, In vivo anti-cancer effects were measured by increased life span of S-180 sarcoma-injected ICR mouse. Immune-modulating effects were analyzed by measuring hemagglutinin titer, appearance of rosette forming cells, lymphocyte proliferation, and phagocytic index in methotrexate-pretreated mice. Results : In vitro assay showed that only Sogam-won showed cytotoxic effect with