대한한방내과학회지 (The Journal of Internal Korean Medicine)
- 제28권2호
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- Pages.217-229
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- 2007
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- 1226-9174(pISSN)
보장지사탕의 항사하작용에 관한 연구
Experimental Studies on the Anti-cathartic Effects of Bojangjisa-tang
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Lee, Seon-Young
(Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Hee University) ;
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Park, Jae-Woo
(Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Hee University) ;
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Ryu, Bong-Ha
(Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Hee University)
- 발행 : 2007.06.30
초록
Objectives : The aim of this experimental study was to investigate the effects of Bojangjisa-tang on anticatharsis by using mice and Guinea pigs. Methods : We observed the actions on gastrointestinal smooth muscles, on the transportability of small and large intestines and on diarrhea induced by castor oil, philocarpine, and barium chloride. Results : Bojangjisa-tang showed alleviation of the contraction of gastrointestinal smooth muscles induced by acetylcholine chloride and barium chloride. The transportability of the large intestine was constrained by Bojangjisa-tang, which also showed substantial anti-cathartic effects on diarrhea induced by castor oil, philocarpine and barium chloride. Conclusion : These results demostrate that Bojangjisa-tang has advantageous effects on drug-induced diarrhea and will contribute to the development of diarrhea treatment through further related studies.