과음하는 성인남자 53 명의 음주패턴과 간 장애에 대한 분석 연구

Analytic Study for Alcohol Consumption-related Parameters in 53 Heavy Drinkers

  • 홍상훈 (동의대학교 한의과대학 간장내과학 교실) ;
  • 조정효 (대전대학교 한의과대학 간장내과학 교실) ;
  • 손창규 (대전대학교 한의과대학 간장내과학 교실)
  • Hong, Sang-Hun (Internal Department of Oriental Medicine College Dongeui University) ;
  • Cho, Jung-Hyo (Internal Department of Oriental Medicine College Daejeon University) ;
  • Son, Chang-Gue (Internal Department of Oriental Medicine College Daejeon University)
  • 발행 : 2007.03.31

초록

Objectives : To investigate the correlations among alcohol consumption, alcoholic liver disorders, physical symptoms, and behaviors in heavy drinkers. Methods : 53 males who self-realized their severe alcohol consumption were enrolled in this study. 10 answers for a questionnaire, serum parameter, sonographic finding and body mass index were attained. The correlations between them were analyzed using Pearson's correlation and Student's t-test. Results : The average consumption of alcohol in these subjects was 2.5-fold over social drinkers. The incidence of alcoholic hepatitis was around 30%, while fatty liver 73%, and abnormal GGT 77%, respectively. No specific correlation between average volume of daily alcoholic consumption and alcohol-related hepatic parameters was shown in this study, but correlative tendency between fatty liver and body mass index was exhibited. Conclusions : This study may indicate that alcoholic liver injuries are caused by not just volume of alcohol consumed but more mixed factors including inherited genetic components, body fat mass, foods and other physical or emotional stress.

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