The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)
- Volume 20 Issue 2 Serial No. 33
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- Pages.10-35
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- 2007
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- 1738-6640(pISSN)
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- 2234-4020(eISSN)
The effects of Ohbaesangami (OBSGM) on the mucosa and skin diseases
오배산가미(五倍散加味)가 점막(粘膜) 및 피부질환(皮膚疾患)에 미치는 영향
- Published : 2007.08.25
Abstract
Objectives : To investigate the effects of Ohbaesangami (OBSGM) on mucosa and skin diseases, anti-microbial and anti-inflammatory tests were performed using several in vitro test models. Results : In anti-microbial test, OBSGM showed the slight inhibitory effect against Propionibacterium acnes (P. acnes) and Staphylococcus aureus (S. aureus). In anti-oxidant test, OBSGM showed the potent radical scavenging activity. In anti-inflammatory test, OBSGM weakly inhibited the lipopolysaccharide (LPS)-induced nitric oxide(NO) release from the RAW 264.7 macrophage cells. OBSGM also inhibited the LPS-induced
Keywords
- Ohbaesangami;
- skin mucosa disease and skin beauty;
- anti-inflammatory;
- collagnease;
- elastase;
- tyrosinase;
- anti-microbial activity;
- $NF-{\kappa}B$;
- MAP kinase;
- MMP-1;
- MMP-2