한방안이비인후피부과학회지 (The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology)
- 제20권1호통권32호
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- Pages.99-114
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- 2007
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- 1738-6640(pISSN)
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- 2234-4020(eISSN)
방풍통성산(防風通聖散)이 아토피 피부염을 유발한 동물모델의 피부 손상에 미치는 영향
The Effects of Bangpungtongsungsan Extract to the Skin Damage on Mice Model after Atopic Dermatitis Elicitation
- 발행 : 2007.04.25
초록
Objectives : Atopic dermatitis has a close relationship with damage of skin barrier function. To investigate the effects of Bangpungtongsungsan(BT) extract to the skin damage on mice model after atopic dermatitis elicitation, this study was done through forcing injury to mice's skin. Methods : The BALB/c mice were distributed into three groups: control(CON) group, atopic dermatitis(AD)-elicited group, Bangpungtongsungsan(BT)-treated group. AD-elicited and BT-treated group were caused AD according to the method of Christophers E., Mrowietz and Minehiro. The BT extract was administered for 48 hours to BT-treated group. We observed changes of external dermal formation, eosinophils in vasculature, lipid formation in stratum corneum, distribution of ceramide, distribution of capillary,
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