Korean Journal of Oriental Medicine (한국한의학연구원논문집)
- Volume 13 Issue 2 Serial No. 20
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- Pages.157-164
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- 2007
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- 1229-3377(pISSN)
Berberine Chloride Inhibits Receptor Activator of $NF-{\kappa}B$ Ligand-induced Osteoclastogenesis via Preventing ERK Activation
- Cheon, Myeong-Sook (Korea Institute of Oriental Medicine) ;
- Kim, Myung-Hee (Laboratory of Chemical Genomics, Korea Research Institute of Chemical Technology) ;
- Lee, Su-Ui (Laboratory of Chemical Genomics, Korea Research Institute of Chemical Technology) ;
- Ryu, Shi-Yong (Laboratory of Phytochemistry Research, Korea Research Institute of Chemical Technology) ;
- Kim, Ho-Kyoung (Korea Institute of Oriental Medicine) ;
- Min, Yong-Ki (Laboratory of Chemical Genomics, Korea Research Institute of Chemical Technology) ;
- Kim, Seong-Hwan (Laboratory of Chemical Genomics, Korea Research Institute of Chemical Technology)
- Published : 2007.08.30
Abstract
An imbalance in bone remodeling that is caused by increased bone resorption over bone formation leads to most adult skeletal diseases including osteoporosis. Since the development of anti-resorptive agents from natural substances has recently gained more interest in the treatment of osteoporosis, we evaluated the effects of 222 natural compounds on receptor activator of