생명과학회지 (Journal of Life Science)

한국생명과학회 (Korean Society of Life Science)
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한약재 조성물의 항산화 활성 및 아질산염 소거능

Antioxidative Activity and Nitrite Scavenging Effect of the Composites Containing Medicinal Plant Extracts

  • 조희숙 (우송대학교 외식조리학과) ;
  • 이수정 (경상대학교 식품영양학과 농업생명과학연구원) ;
  • 신정혜 (남해전문대학 호텔조리제빵과) ;
  • 강민정 (경상대학교 식품영양학과 농업생명과학연구원) ;
  • 조현소 (경상대학교 식품영양학과 농업생명과학연구원) ;
  • 이현지 (경상대학교 식품영양학과 농업생명과학연구원) ;
  • 성낙주 (경상대학교 식품영양학과 농업생명과학연구원)
  • Cho, Hee-Sook (Department of Arts, Woosong University) ;
  • Lee, Soo-Jung (Department of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University) ;
  • Shin, Jung-Hye (Department of Hotel Curinary Arts & Bakery, Namhae College) ;
  • Kang, Min-Jung (Department of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University) ;
  • Cho, Hyun-So (Department of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University) ;
  • Lee, Hyun-Ji (Department of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University) ;
  • Sung, Nak-Ju (Department of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University)
  • 발행 : 2007.08.30
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초록

항산화 활성이 높은 한약재 10종을 대상으로 9종의 조성물(PM-A-PM-I)을 제조하여 항산화 활성을 비교 분석하였다. 한약재 조성물의 DPPH에 대한 전자공여능은 모든 실험군에서 70%이상이었으며, 조성물 중 PM-D, PM-E 및 PM-F가 여타 시료에 비해 유의적으로 전자공여능이 높았다. 환원력도 전자공여능과 동일한 경향이었다. Hydroxyl radical에 대한 항산화 활성은 PM-D가 가장 높았고 다음으로 PM-E였 다. Linoleic acid 에 대한 자동산화 억제능은 PM-A를 제외한 모든 시료에서 50%이상의 활성을 나타내었으며, PM-E, PM-F에서 유의적으로 활성이 높았다. 아질산염 소거능은 선복화가 첨가된 PM-D, PM-E, PM-F에서 유의적으로 높았다. 따라서 9종의한약재 조성물의 항산화활성은 첨가된 한약재의 종류가 유사하였으나 PM-D, PM-E, PM-F 에서 높은 항산화활성을 보인 것은 선복화의 작용이 컸던 것으로 생각되며, 또한 한약재에 함유된 항산화 성분간의 시너지 효과 때문인 것으로 추정된다.

The composites(PM-A-PM-I) of 9 groups containing 7 kinds of hot water extracted medicinal plants were produced and evaluated its antioxidative activity. Each medicinal plants used these composites were analyzed in primer research that its anti oxidative activity was high. In the composites of medicinal plant, electron donating ability was higher than 70% in all sample. PM-D, PM-E and PM-F were significantly higher than others. Reducing power have similar tendency to electron donating ability. PM-D was the strongest in hydroxyl radical scavenging activity, followed by PM-E. In linoleic acid system, antioxidative activity of all sample was showed more than 50%, except PM-A. Especially PM-E and PM-F have significantly higher activity. Nitrite scavenging effect was significantly increased by PM-D, PM-E and PM-F added to Inula Japonica Thunberg. In these results, we suggested that high-er antioxidative activity of PM-D, PM-E and PM-F may be responsible for the contents of phenolic compounds present in Inula Japonica Thunberg. And thought to be enhanced by the synergy effect of the water extracted medicinal plants in the composite.

키워드

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