수술적으로 절제한 유선종양 79례

Mammary Gland Tumors Treated by Surgical Excision : A Retrospective Study in 79 Dogs

  • Chae, Ho-Cheol (Department of Veterinary surgery College of Veterinary Medicine, Seoul National University) ;
  • Byeon, Ye-Eun (Department of Veterinary surgery College of Veterinary Medicine, Seoul National University) ;
  • Lee, Sun-Tae (Department of Veterinary surgery College of Veterinary Medicine, Seoul National University) ;
  • Lim, Ji-Hey (Department of Veterinary surgery College of Veterinary Medicine, Seoul National University) ;
  • Kweon, Oh-Kyeong (Department of Veterinary surgery College of Veterinary Medicine, Seoul National University) ;
  • Kim, Wan-Hee (Department of Veterinary surgery College of Veterinary Medicine, Seoul National University)
  • 발행 : 2007.09.30

초록

Mammary gland tumors are the most common neoplasms occurring in female dogs. The treatments of mammary gland tumors are surgery, chemotherapy, hormonal therapy and radiational therapy, but surgical removal remains widely accepted treatment option for mammary gland tumors. The purpose of this study is to evaluate clinical outcomes of dogs which are performed surgical excision. Medical records were reviewed for dogs(79 cases) with mammary gland tumors treated surgically at Veterinary Medical Teaching Hospital in Seoul National University from 2001 to 2005. While 49 cases(62.0%) were benign, 30 cases(38.0%) were malignant tumors. The mean age of these dogs was 10.4 years old(range $1{\sim}16$ years). The maximal diameter of malignant tumors were various, whereas most of the benign tumors were smaller than 3cm(36 cases, 73.5%). In 12 cases(15.2%), regional lymph nodes were enlarged and lymph nodes of 3 cases had resected surgically. The performed techniques were total mastectomy, regional mastectomy, simple mastectomy, lumpectomy and unilateral mastectomy in order. Twenty-eight cases(35.4%) had postoperative complications consisted of recurrence of tumors, necrosis, dehiscence, delayed healing and edema of limbs. The recurrence rates of benign and malignant mammary gland tumors were 8 cases(16.3%) and 6 cases(20.0%). Metastasis rate was 7 cases(8.9%). Although postoperative complications were no remarkable difference in recurrence rates among surgical techniques in this study, other complications such as edema of limbs, necrosis, dehiscence and delayed healing were remarkable difference as surgical techniques. Therefore, this result suggest that choice of appropriate surgical techniques should be determined according to each patient's physical status and characteristics of tumors.

키워드

참고문헌

  1. Alenza MDP, Pena L, Del Castillo N, Nieto AI. Factors influencing the incidence and prognosis of canine mammary tumors. J Small Animal Prac 2000: 41(7): 287-291 https://doi.org/10.1111/j.1748-5827.2000.tb03203.x
  2. Bojrab MJ. Current Techniques in Small Animal Surgery, 4th ed. Williams & Wilkins. 1998: 579-584
  3. Harvey HJ, Gilbertson SR. Canine Mammary Gland Tumors; Vet Clin North Ame 197: 7(1): 213-219 https://doi.org/10.1016/S0091-0279(77)50018-4
  4. Hashimoto S, Yamamura H, Sato T, Kanayama K, Sakai T. Prevalence of Mammary Gland Tumor of Small Breed Dog in the Tokyo Metropolitan Area. J Vet Epidemiol 2002: 6: 85-90 https://doi.org/10.2743/jve.6.85
  5. Hellmen E, Bergstrom R, Holmberg L, Spangberg IB, Hansson K, Lindgren A. Prognostic Factors in Canine Mammary Tumors: A Multivariate Study of 202 Consecutive Cases. Vet Pathol 1993: 30: 20-27 https://doi.org/10.1177/030098589303000103
  6. Mulligan RM. Mammary cancer in the dog: a study of 120 cases. Am J Vet Res 1975: 36(9): 1391-1396
  7. Novosad CA. Principle of Treatment for mammary Gland Tumors. Clinical Techniques in Small Animal Practice 2003: 18(2): 107-109 https://doi.org/10.1053/svms.2003.36625
  8. Philibert JC, Snyder PW, Glickman N, Glickman LT, Knapp DW, Waters DJ. Influence of Host Factors on Survival in dogswith Malignant Mammary Gland Tumors. J Vet Intern Med 2003: 17: 102-106 https://doi.org/10.1111/j.1939-1676.2003.tb01330.x
  9. Rostami M. Tumors in Domestic Animals Examined during a Ten-year period(l980 to 1989)at Miyazaki University. J Vet Med Sci 1994: 56: 403-405 https://doi.org/10.1292/jvms.56.403
  10. Stephen JW, Gregory EM. Small Animal Clinical Oncology, 3rd ed. Saunders. 2001: 455-477
  11. Fossum TW. Small Animal Surgery, 2nd ed. Mosby. 2002: 637
  12. Withrow SJ, MacEwen EG Surgical Management of Canine Mammary Tumors. Vet Clin North Arne 1975: 5(3): 495-506 https://doi.org/10.1016/S0091-0279(75)50064-X