Childhood Kidney Diseases
- Volume 11 Issue 2
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- Pages.255-263
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- 2007
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- 2384-0242(pISSN)
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- 2384-0250(eISSN)
Outcomes of Chronic Peritoneal Dialysis by Various Modalities in Korean Children - A Single Center Study
소아 환자에서 다양한 복막투석 방법간의 결과 비교-단일기관 연구
- Lee, Sung-Ha (Department of Pediatrics, Seoul National University College of Medicine) ;
- Baek, Jae-Suk (Department of Pediatrics, Seoul National University College of Medicine) ;
- Lee, Hyun-Kyung (Department of Pediatrics, Seoul National University College of Medicine) ;
- Han, Kyoung-Hee (Department of Pediatrics, Seoul National University College of Medicine) ;
- Choi, Hyun-Jin (Department of Pediatrics, Seoul National University College of Medicine) ;
- Lee, Bum-Hee (Department of Pediatrics, Seoul National University College of Medicine) ;
- Cho, Hee-Yeon (Department of Pediatrics, Gachon University Gil Medical Center) ;
- Cheong, Hae-Il (Department of Pediatrics, Seoul National University College of Medicine) ;
- Choi, Yong (Department of Pediatrics, Seoul National University College of Medicine) ;
- Ha, Il-Soo (Department of Pediatrics, Seoul National University College of Medicine)
- 이성하 (서울대학교 의과대학 소아과학교실) ;
- 백재숙 (서울대학교 의과대학 소아과학교실) ;
- 이현경 (서울대학교 의과대학 소아과학교실) ;
- 한경희 (서울대학교 의과대학 소아과학교실) ;
- 최현진 (서울대학교 의과대학 소아과학교실) ;
- 이범희 (서울대학교 의과대학 소아과학교실) ;
- 조희연 ;
- 정해일 (서울대학교 의과대학 소아과학교실) ;
- 최용 (서울대학교 의과대학 소아과학교실) ;
- 하일수 (서울대학교 의과대학 소아과학교실)
- Published : 2007.10.31
Abstract
Purpose : A single center cross sectional retrospective study was performed to compare the outcomes of different peritoneal dialysis(PD) modalities in Korean children. Methods : Among children dialyzed with PD between the year 2004 and 2007, 35 children had reliable data on PD adequacy after 3 to 15 months of dialysis. Subjects were grouped by their modalities; 17, 13 and 5 children were on continuous ambulatory PD(CAPD), continuous cyclic PD(CCPD) and nightly intermittent PD(NIPD), respectively. Body weight and height, number of patients taking anti-hypertensives and laboratory data including biochemical and hemoglobin levels were compared. Dialysis adequacy including weekly Kt/Vurea, creatinine clearance (Ccr) and daily water removal were also compared. Patients were sub-grouped by their peritoneal permeability characteristics. Results : The percentage of patients taking anti-hypertensives, monthly change in Z-scores of body weight and height and laboratory data did not differ among the groups. Patients on CAPD and CCPD showed similar dialysis adequacies. Weekly dialytic Ccr was significantly lower in the NIPD group compared to the others. But total Ccr was not different when residual renal function was added. Weekly dialytic Ccr by CAPD was significantly higher than that of CCPD in low and low-average transporters. Conclusion : We propose that modality can be selected flexibly according to the patients' preferences. And peritoneal permeability characteristics provide valuable information for adjusting PD prescriptions in ultrafiltration failure or in inadequate dialysis. Further study of other clinical performance measures should be performed to clarify the comparable outcomes in different PD modalities.
목 적 : 단일 기관에서 만성복막투석을 시행 받고 있는 소아 환자를 대상으로 후향적 단면연구를 시행하여 복막투석 방법에 따른 투석 결과의 차이가 있는지에 대하여 연구해 보고자 한다. 방 법 : 단일 기관에서 2004년과 2007년 사이에 복막투석을 시행 받았던 환자들 중 투석 후 3개월에서 15개월 사이에 복막투석 적절도에 대한 평가가 이루어졌던 35명의 환자를 대상으로 하였다. 연구 당시 시행하고 있던 복막투석 방법에 따라 CAPD 군, CCPD 군과 NIPD 군으로 환자들을 분류하였고 각각 17명, 13명, 5명의 환자들이 포함되었다. 각 군 사이에 항고혈압제를 복용하고 있는 환자 수, 체중, 신장 및 일반화학 검사와 혈색소 검사를 포함한 혈액 검사 결과의 차이가 있는지 비교 분석하였다. 투석 및 잔여 신기능을 통한 주간
Keywords
- Chronic Peritoneal dialysis;
- Continuous ambulatory peritoneal dialysis;
- Automated peritoneal dialysis;
- Continuous cyclic peritoneal dialysis;
- Nightly intermittent peritoneal dialysis;
- Dialysis adequacy