참고문헌
- McKhann G., Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: a report of the NINCDS-ADRDA Work Group, Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-44 https://doi.org/10.1212/WNL.34.7.939
- Weiner MF. Alzheimer's disease: diagnosis and treatment. Harvard Rev. Psychiatry 1997;4:306-16 https://doi.org/10.3109/10673229709030558
-
Selkoe DJ. Amyloid
$\beta$ -protein and the genetics of Alzheimer's disease. J Biol Chem 1996;271:18295-8 https://doi.org/10.1074/jbc.271.31.18295 - Yankner BA. Mechanism of neuronaldegeneration in Alzheimer's disease. Neuron 1996;16:921-32 https://doi.org/10.1016/S0896-6273(00)80115-4
- Marshall JR, Stimson ER, Ghilardi JR, Vinters HV, Mantyh PW, Maggio JE. Noninvasive imaging of peripherally injected Alzheimer's disease type synthetic ATEX>$\beta$ amyloid in vivo. Bioconjugate Chem 2002;13:276-84 https://doi.org/10.1021/bc010066z
-
Schaadt BK, Hendel HW, Gimsing P, Jonsson V, Pedersen H, Hesse
$^{99m}Tc$ -Aprotinin scintigraphy in amylodosis. J Nucl Med 2003;44:177-83 -
Bornebroek M, Verzijlbergen JF, Haan J, Van Scheyen EJ, Verhoeff NPLG, Pauwels EKJ, et al. Potential for imaging cerebral amyloid deposits using
$ ^{123}I$ -labelled serum amyloid P component and SPET. Nucl Med Commun 1996;17:929-33 https://doi.org/10.1097/00006231-199611000-00002 -
Saito Y, Buciak J, Yang J, Pardridge WM. Vector-mediated delivery of
$^{125}I$ -labeled$\beta$ -amyloid peptide$A{\beta}_{1-40}$ through the blood-brain barrier and binding to Alzheimer disease amyloid of the$A{\beta}_{1-40}$ /vector complex. Proc Natl Acad Sci USA 1995;92:10227-31 - Klunk WE, Debnath ML, Pettegrew JW. Development of small molecule probes for the beta-amyloid protein of Alzheimer's disease. Neurobiol Aging 1994;15:691-8 https://doi.org/10.1016/0197-4580(94)90050-7
- Klunk WE, Debnath ML, Pettegrew JW. Chrysamine-G binding to Alzheimer and control brain: Autopsy study of a new amyloid probe. Neurobiol Aging 1995;16:541-8 https://doi.org/10.1016/0197-4580(95)00058-M
- Ashburn TT, Han H, McGuinness BF, Lansbury PT. Amyloid probes based on Congo Red distinguish between fibrils comprising different peptides. Chem Biol 1996;3:351-8 https://doi.org/10.1016/S1074-5521(96)90118-0
- Han H, Cho C-G, Lansbury PT Jr. Technetium complexes for the quantitation of brain amyloid. J Am Chem Soc 1996;118:4506-7 https://doi.org/10.1021/ja960207l
-
Oya S, Plössl K, Kung M-P, Stevenson DA, Kung HF. Small and neutral TcVO BAT, bisaminoethanthiol (
$N_2S_2$ ) complexes for developing new brain imaging agents. Nucl Med Biol 1998;25: 135-40 https://doi.org/10.1016/S0969-8051(97)00153-4 - Kung HF, Molnar M, Billings J, Blau M. Synthesis and biodistribution of neutral lipid-soluble Tc-99m complexes that cross the blood-brain barrier. J Nucl Med 1984;25:326-32
-
Jeong JM, Kim YJ, Lee YS, Ko JI, Son M, Lee DS, et al. Lipiodol solution of a lipophilic agent,
$^{188]Re$ -TDD, for the treatment of liver cancer. Nucl Med Biol 2001;28:197-204 https://doi.org/10.1016/S0969-8051(00)00208-0 -
Dezutter NA, Dom RJ, de Groot TJ, Bromans GM, Verbruggen AM.
$^{99m}Tc$ -MAMA-chrysamine G, a probe for beta-amyloid protein of Alzheimer's disease. Eur J Nucl Med 1999;26:1392-9 https://doi.org/10.1007/s002590050470 -
Dezutter NA, de Groot TJ, Busson RH, Janssen GA, Verbruggen AM. Preparation of Tc-99m-
$N2_S_2$ conjugates of chrysamine G, potential probes for the beta-amyloid protein of Alzheimer's disease. J Label Cmpd Radiopharm 1999;42:309-24 https://doi.org/10.1002/(SICI)1099-1344(199904)42:4<309::AID-JLCR192>3.0.CO;2-O - Zhen W, Han H, Anguiano M, Lemere CA, Cho C-G, Lansbury PT Jr. Synthesis and amyloid binding properties of rhenium complexes: preliminary progress toward a reagent for SPECT imaging of Alzheimer's disease brain. J Med Chem 1999;42:2805-15 https://doi.org/10.1021/jm990103w
- Klunk WE, Mathis CA, Wang Y. Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and vivo imaging and prevention of amyloid deposition. US Patent 2002/0133019 A1
- Wischik CM, Harrington CR, Rickard JE, Horsley D. Neurofibrillary labels. 2002 PCT WO 02/075318 A2
- Mathis CA, Holt DP, Wang Y, Huang GF, Debmath ML, Klunk WE. Lipophilic 11C-labelled thioflavin-T analogues for imaging amyloid plaques in Alzheimer's disease. J Label Compd Radiopharm 2001;44:S26-S8 https://doi.org/10.1002/jlcr.2580440110
- Mathis CA, Bacskai BJ, Kajdasz ST, McLellan ME, Frosch MP, Hyman BT, et al. A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain. Bioorg Med Chem Lett 2002;12:295-8 https://doi.org/10.1016/S0960-894X(01)00734-X
- Mathis CA, Wang Y, Holt DP, Huang GF, Debnath ML, Klunk WE. Synthesis and Evaluation of 11C-Labeled 6-Substituted 2- Arylbenzothiazoles as Amyloid Imaging Agents. J Med Chem 2003;46:2740-54 https://doi.org/10.1021/jm030026b
- Zhuang Z-P, Kung M-P, Hou C, Skovronsky D, Gur TL, Trojanowski JQ, et al. Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates. J Med Chem 2001;44:1905-14 https://doi.org/10.1021/jm010045q
- Zhuang Z-P, Kung M-P, Hou C, Plössl K, Skovronsky D, Gur TL, et al. IBOX (2-(4'-dimethylaminophenyl)-6-iodobenzoxazole): a ligand for imaging amyloid plaques in the brain. Nucl Med Biol 2001;28:887-94 https://doi.org/10.1016/S0969-8051(01)00264-5
-
Ono M, Kung M-P, Hou C, Kung HF. Benzofuran derivatives as A
$\beta$ -aggregate-specific imaging agents for Alzheimer's disease. Nucl Med Biol 2002;29:633-42 https://doi.org/10.1016/S0969-8051(02)00326-8 -
Zhuang Z-P, Kung M-P, Wilson A, Lee C-W, Plössl K, Hou C, et al. Structure-activity relationship of imidazo[1,2-a]pyridines as ligands for detecting
$\beta$ -amyloid plaques in the brain. J Med Chem 2003;46:237-43 https://doi.org/10.1021/jm020351j -
Chang YS, Jeong JM, Lee Y-S, Kim HW, Rai BG, Kim YJ, et al. Synthesis and evaluation of benzothiophene derivatives as ligands for imaging
$\beta$ -amyloid plaques in Alzheimer's disease. Nucl Med Biol 2006;33:811-820 https://doi.org/10.1016/j.nucmedbio.2006.06.006