Environmental Analysis Health and Toxicology

The Korean Society of Environmental Health and Toxicology (환경독성보건학회)
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Bio-toxicity of Titanium Dioxide Nano Particles (P-25) in Zebrafish Development Stage

Zebrafish 발생기에서 $TiO_2(P-25)$ 나노 입자의 생물 독성

  • Yeo, Min-Kyeong (Department of Environmental Science and Engineering, Kyung Hee University) ;
  • Jo, Yoon-Hee (Department of Environmental Science and Engineering, Kyung Hee University)
  • 여민경 (경희대학교 환경학 및 환경공학) ;
  • 조윤희 (경희대학교 환경학 및 환경공학)
  • Published : 2007.09.30
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Abstract

[ $TiO_2$ ] is widely used because it is non-toxic. Recently, however, nanometer size $TiO_2$ particles (P-25) have been produced and used to increase the photo catalysis efficiency. Nanometer-sized $TiO_2$ is efficient, but due to its small size ($20{\sim}30\;nm$), it can flow into ecosystems and into cells. Thus, it may affect human health. Additionally, $TiO_2$ can produce a second contaminant, OH-radical, which is a health risk for all living organisms during photo degradation reaction. Hence, when nanometer-sized $TiO_2$ flows into natural streams and attaches to living organisms, it will create health risks. We investigated the biological toxicity of this condition in zebrafish embryos. We observed abnormal morphology, hatching rate, and measured the catalase activity to determine anti-oxidation at 100 post fertilization hours. Zebrafish were somewhat affected by $TiO_2$ nanometer sized particles under UV-A (a condition similar to sunlight). Powdered $TiO_2$ is toxic to the zebrafish fly. Even without light, $TiO_2$ particles attached to embryos and flies, having an effect on both.

Keywords

References

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