참고문헌
- Adams, J.M. and Cory, S.: The Bcl-2 protein family: arbiters of cell survival. Science 281:1322-1326, 1998 https://doi.org/10.1126/science.281.5381.1322
- Arends, M.J., Morris, R.G. and Wyllie, A, H.: Apoptosis. The role of the endonuclease. Am. J. Pathol. 136:593-608, 1990
- Bernardi, P., Vassanelli, S., Veronese, P., Colonna, R., Szabo, I. and Zoratti, M.: Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations. J Biol Chem. 267:2934-2939, 1994
- Boulares, A.H., Zoltoski, A.J., Sherif, Z.A., Yakovler, A. and Smulson, M.E.: Roles of DNA fragmentation factor and poly (ADP-ribose) polymerase-1 in sensitization fo fibroblasts to tumor necrosis factor-induced apoptosis. Biochem. Biophys. Res. Commun. 290:796-801, 2002 https://doi.org/10.1006/bbrc.2001.6280
- Cesura, A. M,, Pinard, E., Schubenel, R., Gosetschy, V., Friedlein, A., Langen, H., Polcic, P., Forte, M., Bernardi, P. and Kemp, J.A.: The voltage-dependent anion channel is the target for a new class of inhibitors of the mitochondrial permeability transition pore. J. Biol. Chem. 278:49812-49818, 2003 https://doi.org/10.1074/jbc.M304748200
- Chen, D.F., Schneider, G.E., Martinou, J.C. and Tonegawa, S.: Bc1-2 promotes regeneration of severed axons in mammalian CNS. Nature 385:391-393, 1997 https://doi.org/10.1038/385391a0
- Crompton, M.: Mitochondrial intermembrane junctional complexes and their role in cell death. J. Physiol. 529:11-21, 2000 https://doi.org/10.1111/j.1469-7793.2000.00011.x
- Deng, X., Gao, F. and May, W.S.: Bc12 retards G1/S cell cycle transition by regulating intracellular ROS. Blood 102:3179- 3185, 2003 https://doi.org/10.1182/blood-2003-04-1027
- Duan, Q., Wang, X., Wang, Z., LU, T., Han, Y. and He, S.: Role of mitochondria in neuron apoptosis during ischemiareperfusion injury. J Juazhong Univ Sci Technolog Med Sci. 24:441-444, 2004 https://doi.org/10.1007/BF02831103
- Ellis, R.E., Yuan, J. and Horvitz, H.R.: Mechanisms and functions of cell death. Annu. Rev. Cell Biol. 7:663-698, 1991 https://doi.org/10.1146/annurev.cb.07.110191.003311
- Faulds, D., Goa, K.L. and Benfield, P.: Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders. Drugs 45:953-1040, 1993 https://doi.org/10.2165/00003495-199345060-00007
- Fiskum, G.: Mitochondria participation in ischemic and traumatic neural cell death. J. Neurotrauma. 17:843-855, 2000 https://doi.org/10.1089/neu.2000.17.843
- Folbergrova, J., Li, P.A., Uchino, H., Smith, M.L. and Siesjo, B.K.: Changes in the bioenergetic state of rat hippocampus during 2.5 min of ischemia, and prevention of cell damageby cyclosporin A in hyperglycemic subjects. Exp. Brain Res. 114:44-50, 1997 https://doi.org/10.1007/PL00005622
- Friberg, H. and Wieloch, T.: Mitochondrial permeability transition in acute neurodegeneration. Biochimie. 84:241- 250, 2002 https://doi.org/10.1016/S0300-9084(02)01381-0
- Hassell, T. M., Hefti, A.F.: Drug-induced gingival overgrowth: Old problem, new problem. Crit. Rev. Oral Bio. Med. 2:103- 137, 1991 https://doi.org/10.1177/10454411910020010201
-
Kroll, S.L. and Czyzyk-Krzeska, M.F.: Role of
$H_{2}O_{2}$ and hemecontaining$O_{2}$ sensors in hypoxic regulation of tyrosine hydroxylase gene expression. Am. J. Physiol. 274:167-174, 1998 https://doi.org/10.1152/ajpcell.1998.274.1.C167 - Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S.M., Ahmad, M., Alnemri, E.S. and Wand, X.: Cytochrome c and dATPdependent formation of Aparf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91: 479-489, 1997 https://doi.org/10.1016/S0092-8674(00)80434-1
- Limana, F., Urbanek, K., Chimenti, S., Quaini, F., Leri, A., Kajstura, J., Nadal-Ginard, B., Izumo, S. and Anversa, P.: Bcl-2 overexpression promotes myocyte proliferation. Proc. Natl. Acad. Sci. USA. 99:6257-6262, 2002
- Mascarell, L., Auger, R., Alcover, A., Ojcius, D.M., Jungas, T., Cadet-Daniel, V., Kanellopoulos, J.M. and Truffa-Bachi, P.: Characterization of a gene encoding two isoforms of a mitochondrial protein up-regulated by cyclosporin A in activated T cells. J. Biol. Chem. 279:10556-10563, 2004 https://doi.org/10.1074/jbc.M313770200
- Miyata, K., Omori, N., Uchino, H., Yamaguchi, T., Isshiki, A. and Shibasaki, F.: Involvement of the brainderived neurotrophic factor/TrkB pathway in neuroprotective effect of cyclosporin A in forebrain ischemia. Neuroscience 105:571- 578, 2001 https://doi.org/10.1016/S0306-4522(01)00225-1
- Nicholson, D.W. and Thornberry, N.A.: Caspases: Killer proteases. Trends Biochem. Sci. 22:299-306, 1997 https://doi.org/10.1016/S0968-0004(97)01085-2
- Nor, J.E., Christensen, J., Liu, J., Peters, M., Mooney, D.J., Strieter, R.M. and Polverini, P.J.: Up-Regulation of Bcl-2 in microvascular endothelial cells enhances intratumoral angiogenesis and accelerates tumor growth. Cancer Res. 61:2183- 2188, 2001
- Paul, L.C.: Overview of side effects of immunosuppressive therapy. Transplantation Proceedings. 33:2089-2091, 2001
- Rezzani, R., Corsetti, G., Rodella, L. and Bianchi, R.: Cyclosporine- A treatment prevents apoptosis in rat lumbar ganglion cells. Acta Histochem. 106:129-135, 2004 https://doi.org/10.1016/j.acthis.2003.10.007
- Serkova, N.J., Christians, U. and Benet, L.Z.: Biochemical mechanisms of cyclosporin neurotoxicity. Mol. Interv. 4:97- 107, 2004 https://doi.org/10.1124/mi.4.2.7
- Shiga, Y., Onodera, H., Matsuo, Y. and Kogure, K.: Cyclosporin A protects against ischemia-reperfusion injury in the brain. Brain Res. 595:145-148, 1992 https://doi.org/10.1016/0006-8993(92)91465-Q
- Soeda, J., Miyagawa, S., Sano, K., Masumoto, J., Taniguchi, S. and Kawasaki, S.: Cytochrome c release into cytosol with subsequent caspase activation during warm ischemia in rat liver. Am J Physiol Gastrointest Live Physiol. 281: G1115- 1123, 2001 https://doi.org/10.1152/ajpgi.2001.281.4.G1115
- Sullivan, P.G., Rabchevsky, A.G., Waldmeier, P.C. and Springer, J.E.: Mitochondrial permeability transition in CNS trauma: cause or effect of neuronal cell death? J. Neurosci. Res. 79:231-239, 2005 https://doi.org/10.1002/jnr.20292
- Takahashi, T. and Kamimura, A.: Cyclosporin Apromotes hair epithelial cell proliferation and modulates protein kinase C expression and translocation in hair epithelial cells. J. Invest. Dermatol. 117:605-611, 2001 https://doi.org/10.1046/j.0022-202x.2001.01452.x
- Thornberry, N.A., Rano, T.A., Peterson, E.P., Rasper, D.M., Timkey, T., Garcia-Calvo, M., Houtzager, V.M., Nordstrom, P.A., Roy, S., Vaillancourt, J.P., Chapman, K.T. and Nicholson, D.W.: A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272: 17907-17911, 1997 https://doi.org/10.1074/jbc.272.29.17907
- Tsujimoto, Y. and Shimizu, S.: Bcl-2: Life-or-death switch. FEBS Lett. 466:6-10, 2000a https://doi.org/10.1016/S0014-5793(99)01761-5
- Tsujimoto, Y. and Shimizu, S.: VDAC regulation by the Bcl-2 family of proteins. Cell Death Differ. 7:1174-1181, 2000b https://doi.org/10.1038/sj.cdd.4400780
- Ucjino, H., Elmer, E., Uchino, K., Lindvall, O. and Siesjo, B.K.: A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischemia in the rat. Acta. Physiol. Scand. 155:469-471, 1995 https://doi.org/10.1111/j.1748-1716.1995.tb09999.x
- Wieloch, T.: Mitochondrial involvement in acute neurodegeneration. IUBMB life 52:247-254, 2001 https://doi.org/10.1080/15216540152846064
- Zamzami, N. and Kroemer, G.: The mitochondrion in apoptosis: how Pandora's box opens. Nat. Rev. Mol. Cell Biol. 2:67-71, 2001 https://doi.org/10.1038/35048073