폐에 발생한 다형태 암종 환자에서 전이부위 절제술 후 장기 생존

Long-term Survival following Surgical Resection for Recurrence of Pulmonary Pleomorphic Carcinoma

  • 이진구 (연세대학교 의과대학 흉부외과학교실) ;
  • 박인규 (연세대학교 의과대학 흉부외과학교실) ;
  • 김대준 (연세대학교 의과대학 흉부외과학교실) ;
  • 변천성 (연세대학교 의과대학 흉부외과학교실) ;
  • 조상호 (연세대학교 의과대학 병리학교실) ;
  • 정경영 (연세대학교 의과대학 흉부외과학교실)
  • Lee, Jin-Gu (Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine) ;
  • Park, In-Kyu (Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine) ;
  • Kim, Dae-Joon (Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine) ;
  • Byeon, Cheon-Sung (Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine) ;
  • Cho, Sang-Ho (Department of Pathology, Yonsei University College of Medicine) ;
  • Chung, Kyung-Young (Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine)
  • 발행 : 2007.08.05

초록

폐에서 다형태 암종은 전체 폐암의 $0.1{\sim}0.4%$를 차지하는 매우 드문 악성 종양으로 나쁜 임상경과와 좋지 않은 예후로 알려져 있다. 저자들은 폐에 발생한 다형태 암종 치료 후 발생한 늑골전이에서 외과적 치료를 통해 12년의 무병 장기 생존을 얻었기에 보고하는 바이다.

Pulmonary pleomorphic carcinomas are rare malignant tumors that account for 0.1 to 0.4% of all lung cancers. They are notable for their aggressive clinical behavior and poor prognosis. We report here on a patient who is alive and disease-free 12 years after receiving surgical treatment for the rib recurrence of pulmonary pleomorphic carcinoma.

키워드

참고문헌

  1. Chang YL, Lee YC, Shih JY, Wu CT. Pulmonary pleomophic (spindle) cell carcinoma; Peculiar clinicopathologic manifestations different from ordinary non-small cell carcinoma. Lung Cancer 2001;34:91-7
  2. Beasley MB, Brambilla E, Travis WD. The 2004 World Health Orgnization classification of lung tumors. Semin Roentgenol 2005;40:90-7 https://doi.org/10.1053/j.ro.2005.01.001
  3. Brambilla E, Travis WD, Colby TV, Corrin B, Shimosato Y. The new World Health Organization classification of lung tumours. Eur Respir J 2001;18:1059-68 https://doi.org/10.1183/09031936.01.00275301
  4. World Health Organization. Histological typing of lung tumors. Geneva: WHO. 1981
  5. Raveglia F, Mezzetti M, Panigalli T, et al. Personal experience in surgical management of pulmonary pleomorphic carcinoma. Ann Thorac Surg 2004;78:1742-7 https://doi.org/10.1016/j.athoracsur.2004.04.084
  6. Rossi G, Cavazza A, Sturm N, et al. Pulmonary carcinomas with pleomorphic, sarcomatoid, or sarcomatous elements: a clinicopathologic and immunohistochemical study of 75 cases. Am J Surg Pathol 2003;27:311-24 https://doi.org/10.1097/00000478-200301000-00004
  7. Koss MN, Hochholzer L, Frommelt AR. Carcinosarcomas of the lung: a clinicopathologic study of 66 patiests. Am J Surg Pathol 1999;23:1514-26 https://doi.org/10.1097/00000478-199912000-00009
  8. Pfister DG, Johnson DH, Azzoli CG, et al. American society of clinical oncology treatment of unresectable nonsmall cell lung cancer guideline: update 2003. J Clin Oncol 2004;22:330-53 https://doi.org/10.1200/JCO.2004.09.053