Anti-hyperalgesic Effects of Electroacupuncture Combination of Microcurrent Stimulation in Rat with Induced Inflammation

염증유발 백서에서 전침자극과 미세전류자극의 항-통각과민 효과

  • Kim, Young-Phil (Department of Physical Therapy, Graduate School of Donshin University) ;
  • Lee, Jeong-Woo (Department of Physical Therapy, Hyoin Sanatorium Hospital) ;
  • Seo, Sam-Ki (Department of Physical Therapy, Hyoin Sanatorium Hospital) ;
  • Yoon, Se-Won (Department of Physical Therapy, College of Health and Natural Science, Jinju International University) ;
  • Yoon, Hui-Jong (Department of Physical Therapy, Mokpo Science College) ;
  • Kim, Tae-Youl (Department of Physical Therapy, College of Public Health and Welfare, Donshin University)
  • 김영필 (동신대학교 대학원 물리치료학과) ;
  • 이정우 (효인요양병원 물리치료실) ;
  • 서삼기 (효인요양병원 물리치료실) ;
  • 윤세원 (진주국제대학 물리치료학과) ;
  • 윤희종 (목포과학대학 물리치료과) ;
  • 김태열 (동신대학교 보건복지대학 물리치료학과)
  • Published : 2007.02.25

Abstract

Purpose: The purpose of this study were to examine the anti-hyperalgesic effects of combination of electroacupuncture and microcurrent on anti-hyperalgesia in local hyperalgesia zone. Methods: It used 24 rats for experiment, divided them into control group, electroacupuncture group (EA group), microcurrent group (MC group), combination of electroacupuncture with microcurrent (EA+MC group), caused hyperalgesia by injecting ${\lambda}-carrageenan$ into hindpaw. Thickness of hindpaw, mechanical pain threshold (MPT), thermal pain threshold (TPT), noxious flexion withdrawal reflex (NFR) and somatosensory evoked potential (SEP) were measured immediately after induction, at 24 hours, 48 hours and 72 hours after induction. The electrical stimulation was given once a day for three days, 20min per session. Results: Change of thickness, MPT, and TPT showed significant difference in all groups compared to control group. In particular, there were remarkable difference in EA+ME group. In particular there were remarkable differences in EA group and EA+MC group. Change of NFR(% threshold, % reaction time, % RMS) and SEP showed mainly significant differences in EA group and EA+ME group compared to control group. In particular, there were remarkable difference in EA+ME group. Conclusion: The above results suggest that appropriate combination of microcurrent with electroacupuncture for pain control will be very desirable.

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