The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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Study on anti-oxidant and cosmeceutical activities of Isatis tinctoria L.

판람근(Isatis tinctoria L., 板藍根)추출물의 항산화활성 및 화장품약리활성에 관한 연구

  • Kim, Young-Hun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Cho, Woo-A (Department of Cosmetology Science, Nambu University) ;
  • Cheon, Soon-Ju (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Jang, Min-Jung (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Sung, Ji-Yeun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Jung, Su-Hyun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Choi, Hyang-Ja (Soriso cosmetic) ;
  • Kim, Dae-Ik (Daegu Bio industry Center) ;
  • Kim, Jung-Ok (Daegu Bio industry Center) ;
  • Lee, Chang-Eon (Department of Cosmeceutical Science, Daegu Haany University) ;
  • An, Bong-Jeun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Jin-Tae (Department of Cosmeceutical Science, Daegu Haany University)
  • 김영훈 (대구한의대학교 화장품약리학과) ;
  • 조우아 (남부대학교 향장미용학부) ;
  • 천순주 (대구한의대학교 화장품약리학과) ;
  • 장민정 (대구한의대학교 화장품약리학과) ;
  • 성지연 (대구한의대학교 화장품약리학과) ;
  • 정수현 (대구한의대학교 화장품약리학과) ;
  • 최향자 (소리소화장품) ;
  • 김대익 (대구바이오지원센터) ;
  • 김정옥 (대구바이오지원센터) ;
  • 이창언 (대구한의대학교 화장품약리학과) ;
  • 안봉전 (대구한의대학교 화장품약리학과) ;
  • 이진태 (대구한의대학교 화장품약리학과)
  • Published : 2007.09.28
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Abstract

Objective : In this study, anti-oxidant and cosmeceutical activities of Isatis tinctoria L. extracted from water, ethanol and supercritical fluid condition were confirmed to investigate cosmeceutical activities for utilization as cosmetic ingredient. Methods: Anti-oxidant and cosmeceutical activities were investigated by using electron donating ability, xanthine oxidase, tyrosinase, astringent effect. Result : Isatis tinctoria L. extracts by supercritical fluid, water and ethanol showed good electron donating ability which were 82.7%, 62.6% and 44.8% at the concentration at 1,000ppm, respectively. Xanthine oxidase activity related with purine metabolism was inhibited by ethanol extract about 52.3% at the concentration at 1,000ppm. Tyrosinase inhibition effects, by supercritical fluid extract, ethanol extract and water extract, were 83.3%, 52.9% and 41.2% respectively at 1,000ppm. In the measurement of astringent effect, supercritical fluid extract at the concentration to 5,000ppm showed 85.7% in related activity. The water extract showed 95.9% nitrite scavenging activity at 5,000ppm. Conclusion : According to these results, it is possible that the extract of Isatis tinctoria L. can be used as a new natural material of cosmetic industry.

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