A Case of Duodenal Metastasis from Adenocarcinoma of the Lung

십이지장으로 전이된 폐선암 1예

  • Yoo, Seung Hyun (Department of Internal Medicine, Ewha Womans University School of Medicine) ;
  • Sim, Yun Su (Department of Internal Medicine, Ewha Womans University School of Medicine) ;
  • Lee, Jin Hwa (Department of Internal Medicine, Ewha Womans University School of Medicine) ;
  • Shim, Ki Nam (Department of Internal Medicine, Ewha Womans University School of Medicine) ;
  • Chang, Jung Hyun (Department of Internal Medicine, Ewha Womans University School of Medicine) ;
  • Kim, Yoon Kyung (Department of Radiology, Ewha Womans University School of Medicine) ;
  • Sung, Sun Hee (Department of Pathology, Ewha Womans University School of Medicine)
  • 유승현 (이화여자대학교 의학전문대학원 내과학교실) ;
  • 심윤수 (이화여자대학교 의학전문대학원 내과학교실) ;
  • 이진화 (이화여자대학교 의학전문대학원 내과학교실) ;
  • 심기남 (이화여자대학교 의학전문대학원 내과학교실) ;
  • 장중현 (이화여자대학교 의학전문대학원 내과학교실) ;
  • 김윤경 (이화여자대학교 의학전문대학원 영상의학교실) ;
  • 성순희 (이화여자대학교 의학전문대학원 병리학교실)
  • Received : 2007.07.09
  • Accepted : 2007.08.13
  • Published : 2007.09.30

Abstract

A gastrointestinal metastasis from lung cancer is rare and is quite often found during an autopsy. A 58-year-old man was admitted with left upper back pain and a mass in the left upper lobe on the chest radiograph. The transbronchial lung biopsy revealed an adenocarcinoma of the lung. A gastroduodenoscopy was carried out to evaluate the indigestion and epigastric discomfort. The duodenofibroscopy revealed bulging mucosa on the minor papilla of the duodenum. A metastasis to the duodenum from an adenocarcinoma of the lung was diagnosed by a duodenofibroscopic biopsy of the bulging lesion. We report this rare case of an adenocarcinoma of lung with a metastasis to the duodenum.

원발성폐암의 위장관 전이, 특히 십이지장으로의 전이는 매우 드물며, 부검에서 발견되는 경우가 더 많다. 본 증례의 58세 남자는 왼쪽 등의 통증과 흉부 X-선 촬영에서 좌상엽에 종괴로 의뢰되어 경기관지폐생검 결과 폐선암을 진단 받았으며, 이후 소화불량과 상복부불편감을 호소하여 시행한 위내시경 결과 십이지장 팽대부의 점막 돌출을 발견하여 이에 대한 조직검사에서 폐선암의 십이지장 전이로 밝혀졌다.

Keywords

References

  1. Sternberg A, Giler S, Segal I, Shrnuter Z, Kott I. Small bowel perforation as the presenting symptom of squamous cell carcinoma of the lung. Clin Oncol 1980;6: 181-6
  2. McNeill PM, Wagman LD, Neifeld JP. Small bowel metastases from primary carcinoma of the lung. Cancer 1987;69:1486-9
  3. Stenbygaard LEl, Sorensen JB. Small bowel metastases in non-small cell lung cancer lung. Cancer 1999;33:95-101
  4. Berger A, Cellier C, Daniel C, Kron C, Riquet M, Barbier JP, et al. Small bowel metastases from primary carcinoma of the lung: clinical findings and outcome. Am J Gastroenterol 1999;94: 1884-7. https://doi.org/10.1111/j.1572-0241.1999.01224.x
  5. Leidich RB, Rudolf IE. Small bowel perforation secondary to metastatic lung carcinoma. Ann Surg 1981;193:67-9 https://doi.org/10.1097/00000658-198101000-00011
  6. Antler AS, Ough Y, Pitchumoni CS, Davidian M, Thehno W. Gastrointestinal metastases from malignant tumors of the lung. Cancer 1982;49:170-2 https://doi.org/10.1002/1097-0142(19820101)49:1<170::AID-CNCR2820490134>3.0.CO;2-A
  7. Lee MH, Hong SP, Hyun IG, Lee J, Sohn JH, Kwak ST, et al. A case of duodenal and jejunal metastases from squamous cell carcinoma of the lung. Korean J Gastroenterol 1994;26:191-6
  8. Jang JH, Kim YJ, Kim HD, Yoon HS, Lee YH, Lim YK, et al. A case of obstructive jaundice by ampullary metastasis of small cell lung cancer. Korean J Gastroenterol 1993;26:1386-90
  9. Lee KA, Park JS, Yoo CS, Lee SK, Joo YH, Yoo KS, et al. Two cases of duodenal metastasis from lung cancer with obstructive jaundice. Korean J Gastmlntest Endosc 2000;20:312-6
  10. Yun BR Lee YM, Ann JO, Kim YC, Baek MS, Chung JY, et a1. A case of metastatic large cell carcinoma of the duodenum from the lung. Korean J Med 2000;59:240-4
  11. Stenbygaard LE, Sorensen JB, Olsen JE. Metastatic pattern at autopsy in non-resectable adenocarcinoma of the lung-a study from a cohori of 259 consecutive patients treated with chemotherapy. Acta Oncol 1997;36:301-6 https://doi.org/10.3109/02841869709001267
  12. Yoshimoto A, Kasahara K, Kawashima A. Gastrointestinal metastases from primary lung cancer. Eur J Cancer 2006;42:S157-130
  13. Mosier DM, Bloch RS, Cunningham PL, Dorman SA. Small bowel metastases from primary lung carcinoma: a rarity waiting to be found? Am Surg 1982;58:677-82
  14. Kostakou C, Khaldi L, Flossos A, Kapsoritakis AN, Potamianos SP. Melena: a rare complication of duodenal metastases from primary carcinoma of the lung. World J Gastroenterol 2007;13:1282-5 https://doi.org/10.3748/wjg.v13.i8.1282
  15. Hinoshita E, Nalmhashi H, Walmsugi K, Kaneko S, Hamatake M, Sugimachi K. Duodenal metastasis from large cell carcinoma of the lung: report of a case. Surg Today 1999;29:799-802 https://doi.org/10.1007/BF02482332