70세 이상의 고령에서 발생한 기관지 결핵의 임상적 특징

Clinical Characteristics of Endobronchial Tuberculosis that Develops in Patients over 70 Years of Age

  • 김휘종 (울산병원 내과) ;
  • 김현식 (경상대학교 의과대학 내과학교실) ;
  • 마정은 (경상대학교 의과대학 내과학교실) ;
  • 이승준 (경상대학교 의과대학 내과학교실) ;
  • 함현석 (경상대학교 의과대학 내과학교실) ;
  • 조유지 (경상대학교 의과대학 내과학교실) ;
  • 정이영 (경상대학교 의과대학 내과학교실) ;
  • 전경녀 (경상대학교 의과대학 진단방사선과) ;
  • 김호철 (경상대학교 의과대학 내과학교실) ;
  • 이종덕 (경상대학교 의과대학 내과학교실) ;
  • 황영실 (경상대학교 의과대학 내과학교실)
  • Kim, Hwi Jong (Department of Internal Medicine, Ulsan Hospital) ;
  • Kim, Hyeon Sik (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Ma, Jeong Eun (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Lee, Seung Jun (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Ham, Hyoun Seok (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Cho, Yu Ji (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Jeong, Yi Yeong (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Jeon, Kyoung-Nyeo (Department of Diagnostic Radiology, College of Medicine, Gyeongsang National University) ;
  • Kim, Ho Cheol (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Lee, Jong Deok (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Hwang, Young Sil (Department of Internal Medicine, College of Medicine, Gyeongsang National University)
  • 투고 : 2007.10.12
  • 심사 : 2007.10.29
  • 발행 : 2007.11.30

초록

연구배경: 폐결핵의 발생은 연령이 증가함에 따라 그 빈도가 증가하는 것으로 알려져 있어 기관지 결핵의 발생률도 고령에서 증가할 것으로 생각된다. 본 연구는 70세 이상의 고령에서 발생한 기관지 결핵의 임상적 특징을 알아보고자 하였다. 방 법: 2003년 3월부터 2006년 6월까지 경상대학교병원에서 기관지 결핵으로 진단 받은 74명의 환자(남:여=12:62, 평균나이: $64.6{\pm}16.2$세)를 대상으로 70세 이상 환자군과 70세 미만 환자군으로 나누어 임상적 특징을 후향적으로 조사하였다. 결 과: 1) 70세 이상의 환자는 41명(55%), 70세 미만의 환자는 33명(45%)이었다. 2) 양군 모두에서 가장 흔한 증상은 기침이었으며, 호흡곤란의 빈도는 70세 이상 환자군이 70세 미만 환자군보다 높았다(31.7% vs. 12.1%). 3) 기관지내시경 소견상 70세 이상의 환자군이 70세 미만의 환자군보다 건락성 괴사형의 비율은 낮았고(39% vs. 66.7%), 부종 충혈형은 상대적으로 높았다(53.7% vs. 27.2%)(p<0.05). 4) 병변의 위치는 기관 또는 주 기관지를 침범하는 경우가 70세 이상의 환자군이 70세 미만의 환자군보다 유의하게 많았다(9.7% vs. 30.3%). 5) 객담 및 기관지 세척액의 항산균 도말 양성률과 배양 양성률은 유의한 차이가 없었다. 결 론: 70세 이상의 고령에서도 기관지 결핵은 흔히 관찰할 수 있으며, 70세 미만의 기관지 결핵 환자와는 다른 몇 가지 임상양상을 보였다.

Background: The possibility of developing pulmonary tuberculosis usually increases with increasing age. Therefore, the incidence of endobronchial tuberculosis in older people may increase. We evaluated the clinical characteristics in patients with endobronchial tuberculosis above the age of 70 years. Methods: We enrolled 74 patients (12 males and 62 females; mean age $64.6{\pm}16.2 $years) that were diagnosed with endobronchial tuberculosis from March 2003 to July 2006 at Gyeongsang University Hospital. We retrospectively evaluated the clinical characteristics of endobronchial tuberculosis for patients 70 years or older (older group) and for patients below the age of 70 years (younger group). Results: The number of patients in the older group was 41 (55%). Cough was the most common symptom in the two groups of patients and dyspnea on exertion was more common in the older group of patients than in the younger group of patients (31.7% vs. 12.1%). The actively caesating type of disease was more common in the younger group of patients than in the older group of patients (66.7% vs. 39%). The edematous type of disease was more common in the older group of patients than in the younger group of patients (53.7% vs. 27.2%) (p<0.05). Tracheal and main bronchial involvement of lesions were more common for the younger group of patients than for the older group of patients (30.3% vs. 9.7%) (p<0.05). Conclusion: Endobronchial tuberculosis was commonly observed in patients older than 70 years and this group of patients had some clinical characteristics that were different from the younger group of patients.

키워드

참고문헌

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