Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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A Case of Hypospadias in Korean Native Calf

한우 송아지에서의 요도하열(hypospadias) 발생 증례

  • Published : 2007.06.30
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Abstract

Hypospadias is a malformation in which the urethra open on the ventral side of the penis and its frequency is about from 0.3% to 0.5% male birth in human. It is considered a disorder both genetic and environmental factors involves in pathogenesis. A KNC(Korean native calf) showing symptoms of fusion defect of the male ventral urethra, penile defect, bifid scrotum and low body weigh was born. To prevent an ascending urinary tract infection, dermatitis and loss of hair, surgical operation was performed to make a genitals like a female. After the operation, the KNC got a regenerative hair and normal urination. However the KNC became anorexia, loss in weight and weak. Seventy days after birth, the KNC died. The view of autopsy was a yellowish hepatomegaly, hydronephrosis, closed ureter and complex disorder in interanl organ. The symptoms of hepatomegaly and hydronephrosis could be due to a fluid therapy as a consequence of ureter obstruction. The normal urination of the KNC before it got sick, suggested that ureter obstruction in the case of this KNC was formed at its postnatal growth stage.

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References

  1. Ader PL. Hobson HP. Hypospadias: review ofthe veterinary literature and a report of three cases in the dog. J Am Animal Assoc 1978; 14, 721-727
  2. Allera A. Herbst MA. Griffin JE. Wilson JP. Schweikert HU. McPhaul MJ. Mutations of the androgen receptor coding sequence are influenct in patients with isolated hypospadias. J Clin Endocr Metab 1995; 80, 2697-2699 https://doi.org/10.1210/jc.80.9.2697
  3. Baskin LS. Hypospadias: a critical analysis of cosmetic outcomes using photography. BJU Int 2001; 87, 534-539 https://doi.org/10.1046/j.1464-410X.2001.00092.x
  4. Baskin LS. Colborn T. Himes K. Hypospadias and endocrine disruption: is there a Connection? Environ Health Perspect 2001; 109, 1175-1183 https://doi.org/10.2307/3454866
  5. Baskin LS, Ebbers BB. Hypospadiasis: anatomy, etiology and technique. J Pediatric Surgery 2006; 41: 463-472 https://doi.org/10.1016/j.jpedsurg.2005.11.059
  6. Bleul U, Theiss F, Rtten M, Khn W. Clinical, cytogenetic and hormonal findings in a stallion with hypospadias-A case report. The veterinary Journal 2006
  7. Dennis SM. Hypospadias in merino lambs. Vet Rec 1979; 105, 94-96
  8. Fredell L. Iselius L. Collins A. Hansson E. Holmner S. Lundquist L. Lackgren G Pedersen J. Stenberg A. Westbacke G. Nordenskjold A. Complex segregation analysis of hypospadias. Hum Genet 2002; 111 , 231-234 https://doi.org/10.1007/s00439-002-0799-y
  9. Foster PM. Mylchreest E. Gaido KW. Sar M. Effects of phthalate esters on the developing reproductive tract of male rats. Hum Reprod Update 2001; 7, 231-235 https://doi.org/10.1093/humupd/7.3.231
  10. Hayes Jr HM, Wilson GP. Hospital incidence of hypospadias in dog in North America. Vet Rec 1986; 118, 605-607 https://doi.org/10.1136/vr.118.22.605
  11. Herzog A. Pareys Lexikon der Syndrome. Parey Buchverlag, Berlin 2001
  12. Hynes PJ. Fraher JP. The development of the male genitourinary system. 1. The origin ofthe urorectal septum and the formation ofthe perineum. British J Plastic Surgery 2004; 57, 27-36 https://doi.org/10.1016/j.bjps.2003.08.019
  13. King GJ. Johnson EH. Hypospadias in a Himalayan cat. J Small Animal Prac 2000; 41 , 508-510 https://doi.org/10.1111/j.1748-5827.2000.tb03973.x
  14. Mcfarland LZ. Perineal hypospadias in male lambs. J Am Vet Med Assoc 1958; 57, 27-36
  15. Mathew R. Docimo S. Hypospadiasis. In Encyclopedia of Reproduction.Vol 2. San Diego, Academic Press. 1999: 759-764
  16. Nicoletti A, Baldazzi L, Balsamo A, BarP L, Pirazzoli P, Gennari M, Radetti G, Cacciari E, Cicognani A. SRD5A2 gene analysis in an Italian population ofunder-masculinized 46,XY subjects. Clinical Endocrinology 2005; 63: 375-380 https://doi.org/10.1111/j.1365-2265.2005.02348.x
  17. Saperstein G. Leopold HW. Dennis SMW. Congenital defects ofsheep. J Am Vet Med Assoc 1975; 167, 314-322
  18. Saunders PJ. Ladds PW. Congenital and development abnormalities of the genitalia of slaughtered bulls. Australian Veterinary Joumal 1978; 54, 10-13 https://doi.org/10.1111/j.1751-0813.1978.tb00261.x
  19. Smith KC, Brown P, Parkinson n. Hypospadias in rams. Vet Rec 2006; 158, 789-795 https://doi.org/10.1136/vr.158.23.789
  20. 허태영, 강석진, 최창용, 정영훈, 조용일, 손동수, 류일선, 김현섭, 서국현. 젖소 송아지에서 반전성열체 (schistosomus reflexus) 1 례. 한국임상수의학회지 2005; 22(4): 408-411
  21. 허태영, 강석진, 최창용, 정영훈, 조용일, 류일선, 손동수, 김현섭, 서국현. 젖소 흉부결합체 송아지 1 례. 대한수의학회지 2006; 46(1): 63-66