Journal of dental hygiene science (치위생과학회지)
- Volume 7 Issue 1
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- Pages.31-35
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- 2007
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- 1598-4478(pISSN)
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- 2233-7679(eISSN)
Antiproliferative Effects of Caesalpinia sappan Extract on Human Epithelial Cell Line HaCaT and Cancer Cell Lines
인체 상피세포주와 암세포주에 대한 소목 추출물의 증식억제 효과
- Han, Man-Deuk (Department of Biology, Soonchunhyang University) ;
- Kim, Eung-Kwon (Department of Dental Hygiene, Suwon Science college)
- Received : 2007.02.20
- Accepted : 2007.03.22
- Published : 2007.03.30
Abstract
Caesalpinia sappan L. (Leguminosae) is an oriental medicinal herb distributed in China and Taiwan, and its heartwood has been traditionally used as an analgesic, a therapy for thrombosis or tumor. This study was to investigate the proliferation and inhibition effects of Caesalpinia sappan extracts against human epithelial cell and cancer cell lines. The methanol extract of dried C. sappan heartwood was evaporated (KS-6), and then sequentially extracted by hexane (KS-01), chloroform (KS-02), ethyl acetate (KS-03), n-butanol (KS-04), and water (KS-05). After 48 hr of exposure, these fractions at a concentration of