한방비만학회지 (Journal of Korean Medicine for Obesity Research)
- 제7권1호
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- Pages.1-7
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- 2007
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- 1976-9334(pISSN)
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- 2288-1522(eISSN)
비만처방에서 마황의 임상활용에 대한 고찰;용량, 효과, 부작용 등의 측면에서
Clinical Application of Ma Huang in the Obesity Treatment
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Song, Yun-Kyung
(Department of Oriental Rehabilitation Medicine, College of Oriental Medicine, Kyungwon University) ;
- Lim, Hyung-Ho (Department of Oriental Rehabilitation Medicine, College of Oriental Medicine, Kyungwon University)
- 발행 : 2007.06.30
초록
Background : Use of Ma Huang is controversial. Multiple reports of adverse effects led the U.S. Federal Drug Administration (FDA) to announce about prohibiting dietary supplements containing ephedrine alkaloids/Ma Huang. Objective : The objective of the study was to review the evidence from literature and rigorous clinical trials on the dosage, effectiveness, and adverse effects. Methods : Literature searches were conducted in U.S. FDA database after 2003 and digital Uibujeonok(醫部全錄). Hand searches of medical journal and bibliographies of identified articles were conducted. Results : Ma Huang has been used in Korean Oriental Medicine to treatment asthma and other ailments. Recently, Ephedrine/Ma Huang are used for weight loss or to enhance athletic performance in Europe and America, Korea. Ephedrine/Ma Huang are associated with increased risk of psychiatric, autonomic, or gastrointestinal symptoms, and heart palpitations. In addition to that, a risk of serious adverse events, including heart attack, stroke, epilepsy and psychiatric problem are also have been reported. Therefore, max dose of total alkaloids of ephedrine is studied in need of a specialist's part. Conclusion : In most reports, Ma Huang effectively promoted short-term weight loss and enhancement of athletic performance, But, safety with long-term use requires further investigation.