Natural Product Sciences

  • 제13권2호
  • /
  • Pages.164-168
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  • 2007
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  • 1226-3907(pISSN)
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  • 2288-9027(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

Activity of Essential Oil from Mentha piperita against Some Antibiotic-Resistant Streptococcus pneumoniae Strains and Its Combination Effects with Antibiotics

  • 발행 : 2007.06.30
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초록

To investigate natural antibiotics from plant essential oils and to evaluate their synergism with current antimicrobial drugs in inhibiting antibiotic-resistant strains of Streptococcus pneumoniae. The minimal inhibitory concentrations (MICs) of eleven plant essential oils and their main components were established for two antibiotic-susceptible and two antibiotic-resistant strains of S. pneumoniae, using broth microdilution tests. Potential synergism with oxacillin, norfloxacin, or erythromycin was evaluated using a checkerboard microtitre assay. Among the tested oils, Mentha piperita oil and its main component, menthol, exhibited the strongest inhibitory activities against all of the tested strains. The activity of antibiotics against antibiotic-resistant strains of S. pneumoniae was enhanced significantly by combination with Mentha piperita oils and its main component, menthol. In conclusion, the combination Mentha piperita essential oil or menthol with antibiotics could be used to reduce the effective dose of antibiotic and to modulate the resistance of S. pneumoniae strains.

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참고문헌

  1. Aflatuni, A., Uusitalo, J., Ek, S., and Hohtola, A., Variation in the amount of yield and in the extract composition between conventionally produced and micropropagated peppermint and spearmint. J. Essent. Oil Res., 17, 66-70 (2005) https://doi.org/10.1080/10412905.2005.9698833
  2. Appelbaum, P.C., Antimicrobial resistance in Streptococcus pneumoniae : An overview. Clin. Infec. Dis., 15, 77-83 (1992) https://doi.org/10.1093/clinids/15.1.77
  3. Ardanuy, C., Fenoll, A., Berron, S. Calatayud, L, and Linares, J., Increase of the M Phenotype among Erythromycin-Resistant Streptococcus pneumoniae Isolates from Spain Related to the Serotype 14 Variant of the Spain super (9V)-3 Clone. Antimicrob. Agents. Chemother. 50, 3162-3165 (2006) https://doi.org/10.1128/AAC.00269-06
  4. Baron, E.J., Peterson, L.R., and Finegold, S.M., Diagnostic Microbiology, Mosby, St Louis, pp. 350 (1994)
  5. Ben Arfa, B., Combes, S., Preziosi-Belloy, L., Gontard, N., and Chalier, P., Antimicrobial activity of carvacrol related to its chemical structure. Lett. Appl. Microbiol. 43(2), 149-154 (2006) https://doi.org/10.1111/j.1472-765X.2006.01938.x
  6. Esposito, S. and Principi, N., Emerging resistance to antibiotics against respiratory bacteria; impact on therapy of community-acquired pneumonia in children. Drug Resist. Update 5, 73-87 (2002) https://doi.org/10.1016/S1368-7646(02)00018-3
  7. Filoche, S.K., Doma, K., and Sissons, D.H., Antimicrobial effects of essential oils in combination with chlorhexidine digluconate. Oral Microbiol. Immun. 20, 221-225 (2005) https://doi.org/10.1111/j.1399-302X.2005.00216.x
  8. Ho, P.K., Lam, K.F., Chow, F.K.H., Lau, Y.L., Wong, S.S.Y., Cheng, S.L. F., and Chiu, S.S., Serotype distribution and antimicrobial resistance patterns of nasopharyngeal and invasive Streptococcus pneumoniae isolates in Hong Kong children. Vaccine 22, 3334-3339 (2004) https://doi.org/10.1016/j.vaccine.2004.02.038
  9. Husueh, O.-R., Decreasing rates of resistance to penicillin, but not erythromycin, in Streptococcus pneumoniae after introduction of a policy to restrict antibiotic usage in Taiwan. Clin. Microbiol. Infect. 11, 925-927 (2005) https://doi.org/10.1111/j.1469-0691.2005.01245.x
  10. Imai, H., Osawa, K., Yasuda, H., Hamashima, H., Arai, T., and Sasatsu, M., Inhibition by the essential oils of peppermint and spearmint of the growth of pathogenic bacteria. Microbes 106, 31-39 (2001)
  11. Jay, J.M. and Rivers, C.M., Antimicrobial activity of some food flavoring compounds. J. Food Safety 6, 129-139 (1984) https://doi.org/10.1111/j.1745-4565.1984.tb00609.x
  12. Koneman, E.W., Allen, S.D. Janda, W.M., Schreckenberger, P.C., and Winn, W.C., Diagnostic Micrbiology, J. B. Lippincott Company, pp. 437 (1992)
  13. Marcum, D.B. and Hanson, B.R., Effect of irrigation and harvest timing on peppermint oil yield in California. Agr. Water Manage. 82, 118-128(2006) https://doi.org/10.1016/j.agwat.2005.07.022
  14. Mimica-Dukic, N., Bozin, B., Sokovic, M., Mihajlovic, B., and Matavuij, M., Antimicrobial and antioxidant activities of three Mentha species essential oils. Planta Med. 69, 413-419 (2003) https://doi.org/10.1055/s-2003-39704
  15. Schelz, Z. Molnar, J., and Hohmann, J., Antimicrobial and antiplasmid activities of essential oils. Fitoterapia 77, 279-285 (2006) https://doi.org/10.1016/j.fitote.2006.03.013
  16. Shin, S. and Lim, S., Antifungal activities of herbal essential oils alone and in combination with ketoconazole against Trichophyton spp. J. Appl. Microbiol. 97, 289-1296 (2004)
  17. Shin, S. and Kim J.H., In vitro inhibitory activities of essential oils from two Korean Thymus species against antibiotic-resistant pathogens. Arch. Pharm. Res. 28, 897-901 (2005) https://doi.org/10.1007/BF02973874
  18. Shin, S. and Pyun, M.-S., Antifungal effects of the volatile oils from Allium plants against Trichophyton species and synergism of the oils with ketoconazole. Phytomedicine 13, 394-400 (2006) https://doi.org/10.1016/j.phymed.2005.03.011
  19. Teale, C.J., Antimicrobial resistance and the food chain. J. Appl. Microbiol. 92, 85-89 (2002) https://doi.org/10.1046/j.1365-2672.92.5s1.20.x
  20. Trombetta, D., Castelli, F., Sarpietro, M.G., S., Venuti, V., Cristani, M., Daniele, C., Saija, A., Mazzanti, G. and Bisigano G., Mechanism of antibacterial action of three monoterpenes. Antimicrob. Agents Chemother. 49, 2474-2478 (2005) https://doi.org/10.1128/AAC.49.6.2474-2478.2005
  21. White, R.L., Burgess, D.S., Manduru, M., and Bosso, J.A., Comparison of three diffenent in vitro methods of detecting synergy: time-kill, checkerboard, and E test. Antimicrob. Agents Chemother. 40, 1914-1918 (1996)