The Journal of Korean Obstetrics and Gynecology (대한한방부인과학회지)
- Volume 20 Issue 1
- /
- Pages.61-83
- /
- 2007
- /
- 1229-4292(pISSN)
- /
- 2508-3619(eISSN)
Effects of Keukhachukeo-Tang on the Development of Experimentally-induced Endometriosis in Rats
격하축동탕(膈下逐疼湯)이 실험적으로 유발된 흰쥐의 자궁내막증에 미치는 영향
- Kim, Chul-Soo (Dept. of Oriental Gynecology, College of Oriental Medicine, Se-Myung University) ;
- Lee, Dong-Nyung (Dept. of Oriental Gynecology, College of Oriental Medicine, Se-Myung University) ;
- Seo, Il-Bock (Dept. of Oriental Gynecology, College of Oriental Medicine, Se-Myung University) ;
- Kim, Hyung-Jun (Dept. of Oriental Gynecology, College of Oriental Medicine, Se-Myung University)
- 김철수 (세명대학교 한의과대학 부인과학교실) ;
- 이동녕 (세명대학교 한의과대학 부인과학교실) ;
- 서일복 (세명대학교 한의과대학 부인과학교실) ;
- 김형준 (세명대학교 한의과대학 부인과학교실)
- Published : 2007.02.28
Abstract
Purpose: This study was performed to investigate the effects of Keukhachukeo-Tang (KCT) on the development of experimentally-induced endometriosis in rats. Methods : Endometriosis was induced in rats by autotransplanting uterine tissue to the peritoneum and devided them into three groups: (1) sham-operated group (n=8), (2) surgically induced endometriosis and untreated control group (n =8), (3) surgically induced endometriosis and KCT treated group. KCT (1,200 mg/head) was orally administrated for 15 days after operation. Then we measured the body weight, the volumes of endometriotic implants. The weight (body, left uterus and ovaries) and concentrations of cytokines (MCP-1, TNF-