Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Development of Biologically Active Compounds from Edible Plant Sources-XVII. Chemical Constituents from the Aerial Parts of Artemisia princeps PAMPANINI (Sajuarissuk)

식용식물자원으로부터 활성물질의 탐색-XVII. 싸주아리쑥(Artemisia princeps PAMPANINI, Sajuarissuk) 지상부의 화학성분

  • Yoo, Jong-Su (Graduate School of Biotechnology & Plant Metabolism Research Center, Kyung Hee University) ;
  • Bang, Myun-Ho (Ganghwa Agricultural R&D Center) ;
  • Ahn, Eun-Mi (Department of Herbal Foodceutical Science, Daegu Haany University) ;
  • Song, Myoung-Chong (Graduate School of Biotechnology & Plant Metabolism Research Center, Kyung Hee University) ;
  • Chung, Hae-Gon (Ganghwa Agricultural R&D Center) ;
  • Jeong, Tae-Sook (National Research Laboratory of Lipid Metabolism & Atherosclerosis, KRIBB) ;
  • Lee, Kyung-Tae (Department of Biochemistry, College of Pharmacy, Kyung Hee University) ;
  • Choi, Myung-Sook ;
  • Baek, Nam-In (Graduate School of Biotechnology & Plant Metabolism Research Center, Kyung Hee University)
  • 유종수 (경희대학교 생명공학원 및 식물대사연구센터) ;
  • 방면호 (강화군농업기술센터 특화작목연구소) ;
  • 안은미 (대구한의대학교 한방식품약리학과) ;
  • 송명종 (경희대학교 생명공학원 및 식물대사연구센터) ;
  • 정해곤 (강화군농업기술센터 특화작목연구소) ;
  • 정태숙 (한국생명공학연구원 지질대사연구실) ;
  • 이경태 (경희대학교 약학대학 약품생화학교실) ;
  • 최명숙 (Department of Food Science and Nutrition, Kyungpook National University) ;
  • 백남인 (경희대학교 생명공학원 및 식물대사연구센터)
  • Published : 2007.03.31
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Abstract

The aerial parts of Artemisia princeps PAMPANINI were extracted with 80% aqueous MeOH and the concentrated extract was partitioned with EtOAc, n-BuOH and $H_2$O, successively. From the EtOAc fraction, five compounds were isolated through the repeated silica gel and ODS column chromatog-raphies. They were determined as friedelin (1), ${\beta}$-amyrin (2), ${\beta}$-amyrin acetate (3), camphanediol (4) and hispidulin (5) on the basis of spectral data, respectively.

싸주아리쑥 지상부를 80% MeOH 용액으로 추출하고, 얻어진 추출물을 EtOAc, n-BuOH 및 $H_2O$로 용매 분획하였다. 이중 EtOAc 분획으로부터 silica gel과 ODS column chromatography로 정제하여 5개의 화합물을 분리하였다. 각 화합물의 화학구조는 NMR, MS 및 IR 등의 스펙트럼 데이터를 해석하여, friedelin (1), ${\beta}$-amyrin (2), ${\beta}$-amyrin acetate (3), camphanediol (4), hispidulin (5)으로 동정하였다. 이 화합물들은 싸주아리쑥에서는 처음 분리되었다.

Keywords

References

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