환아의 혈액과 변에서 분리된 Shigella flexneri의 생화학적 성상, 항균제 감수성 및 Pulsed-Field Gel Electrophoresis 분석

Biochemical Characteristics, Antimicrobial Susceptibility and Pulsed-Field Gel Electrophoresis Patterns of Shigella flexneri Isolated from Blood and Fecal Specimens of Pediatric Patients

  • 김신무 (원광보건대학 임상병리과) ;
  • 임채원 (원광보건대학 임상병리과) ;
  • 소향아 (전라북도 보건환경연구원) ;
  • 심은숙 (원광보건대학 임상병리과) ;
  • 김은숙 (전북대학교 대학원 생물학과) ;
  • 이규식 (원광보건대학 임상병리과) ;
  • 정윤섭 (연세대학교 의과대학 진단검사의학과 및 세균내성연구소)
  • Kim, Shin-Moo (Department of Clinical Laboratory Science. Wonkwang Health College) ;
  • Lim, Chae-Won (Department of Clinical Laboratory Science. Wonkwang Health College) ;
  • So, Hyang-Ah (Department of Microbiology, Jellabukdo Institute of Health & Environmental) ;
  • Shim, Eum-Sook (Department of Clinical Laboratory Science. Wonkwang Health College) ;
  • Kim, Eun-Sook (Division of Biological Science,Chonbuk National University) ;
  • Lee, Kyu-Sik (Department of Clinical Laboratory Science. Wonkwang Health College) ;
  • Chong, Yunsop (Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine)
  • 발행 : 2007.12.31

초록

Shigellosis is the most common bacterial gastroenteritis both in developing and developed countries, but bacteremia due to Shigella spp. is very rare. In developed countries recent shigellosis is mostly caused by S. sonnei, but S. flexeri infection is rare. We had rare cases of S. flexeri infections in a family in the Jeonbuk Province: an 8-year-old boy with bacteremic shigellosis and 10- and 12-year-old brothers with diarrhea. The isolates had identical biochemical characteristics, and were resistant to ampicillin, chloramphenicol, and co-trimoxazole. PFGE pattern of Not I-restricted genomic DNA suggested that the isolate from blood was closely related to the two strains isolated from stool which had an identical PFGE pattern.

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