Journal of Periodontal and Implant Science

  • 제37권2호
  • /
  • Pages.237-249
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  • 2007
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  • 2093-2278(pISSN)
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  • 2093-2286(eISSN)
대한치주과학회 (Korean Academy of Periodontology)
권호 표지

천공형 티타늄 막의 조기 노출이 수직 골 형성에 미치는 영향

The effect of early membrane exposure on exophytic bone formation using perforated titanium membrane

  • 김은정 (경희대학교 치의학전문대학원 치주과학교실, 구강생물학연구소) ;
  • 허익 (경희대학교 치의학전문대학원 치주과학교실, 구강생물학연구소) ;
  • 권영혁 (경희대학교 치의학전문대학원 치주과학교실, 구강생물학연구소) ;
  • 박준봉 (경희대학교 치의학전문대학원 치주과학교실, 구강생물학연구소) ;
  • 정종혁 (경희대학교 치의학전문대학원 치주과학교실, 구강생물학연구소)
  • Kim, Eun-Jung (Department of Periodontology and Institute of Oral Biology, School of Dentistry, Kyung Hee University) ;
  • Herr, Yeek (Department of Periodontology and Institute of Oral Biology, School of Dentistry, Kyung Hee University) ;
  • Kwon, Young-Hyuk (Department of Periodontology and Institute of Oral Biology, School of Dentistry, Kyung Hee University) ;
  • Park, Joon-Bong (Department of Periodontology and Institute of Oral Biology, School of Dentistry, Kyung Hee University) ;
  • Chung, Jong-Hyuk (Department of Periodontology and Institute of Oral Biology, School of Dentistry, Kyung Hee University)
  • 발행 : 2007.06.30
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초록

This study was performed to evaluate the effect of membrane exposure on new bone formation when guided bone regeneration with perforated titanium membrane on atrophic alveolar ridge. The present study attempted to establish a GBR model for four adult beagle dog premolar. Intra-marrow penetration defects were created on the alveolar ridge(twelve weeks after extraction) on the mandibular premolar teeth in the beagle dogs. Space providing perforated titanium membrane with various graft material were implanted to provide for GBR. The graft material were demineralized bovine bone(DBB), Irradiated cancellous bone(ICB) and demineralized human bone powder(DFDB). The gingival flap were advanced to cover the membranes and sutured. Seven sites experienced wound failure within 2-3weeks postsurgery resulting in membrane exposure. The animals were euthanized at 4 weeks postsurgery for histologic and histometric analysis. The results of this study were as follows: 1. There was little new bone formation at 4 weeks postsurgery. irrespectively of membrane exposure. 2. There was significant relationship between membrane exposure and bone graft resorption(P<0.05), but no relation between membrane exposure and infiltrated connective tissue. 3. There was much bone graft resorption on DFDB than ICB and DBB. 4. The less exposure was on the perforated titanium membrane, the more dense infiltrated connective tissue was filled under the membrane when grafted with ICB and DBB. but there was no relationship between the rate of membrane exposure and the percentage of infiltrated connective tissue area and no relationship between the percentage of the area in the infiltrated connective tissue and in the residual bone graft. Within the above results, bone formation may be inhibited when membrane was exposed and ICB and DBB were more effective than DFDB as a bone graft material when guided bone regeneration.

키워드

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