DOI QR코드

DOI QR Code

Comarison of Major Constituents in Acanthopanax Taxa and Variety Cheongsong in Korea by GC-MS

GC-MS에 의한 오갈피나무 분류군과 청송 변종의 주요 성분 비교

  • 조경순 (부산광역시 보건환경연구원) ;
  • 구평태 (부산광역시 보건환경연구원) ;
  • 허만규 (동의대학교 분자생물학과)
  • Published : 2007.05.25

Abstract

Species of genus Acanthopanax(Araliaceae) are long-lived trees primarily distributed throughout East Asia. These species are regarded as medically and ecologically important in Korea. A variety of Cheongsong in Korea is one of these cultivated varieties, however this variety is much longer(>100 years) than those of other cultivated groups. The components of variety of Acanthopanax in Cheongsong were analyzed for the first time and were compared to those of all Acanthopanax taxa in Korea. Nineteen components were specific to variety in Cheongsong. The main components of this variety were $\beta$-caryophyllene, hexadecanoic acid and ethyl stearate. Although some components are differ from each other, variety Cheongsong was similar to A. senticosus at phonetic topology with content of the chemicals, In addition, six species of genus Acanthopanax were investigated to compare the major chemical components by GC-MS.

오갈피나무속 식물종은 주로 동아시아에 분포하는 다년생 목본류이다. 이 속의 식물 종은 한국에서 약 6종으로 알려져 있으며 일부 종은 약용으로 사용되어 경제적으로 매우 중요하다. 청송변종은 청송에서 100년 이상 재배되고 있는데 그 기원이 불분명하여 주요 생화학적 성분을 GC-MS로 분석하여 다른 종과 비교하였다. 분석한 화학성분 중 19개가 청송변종에 특이하였는데 $\beta$-caryophyllene, hexadecanoic acid, 그리고 ethyl stearate 등이다. 청송변종은 오갈피나무와 비록 일부 성분에 있어 차이가 나지만 전체적인 분류학적 위상에서 다른 종에 비해 가장 유사하여 오갈피나무에서 분지한 것으로 판단된다. 또 오갈피나무속 6종에 대한 성분 차이가 GC-MS로 잘 구분되어 화학성분에 의해 종간 차이가 있음이 밝혀졌다.

Keywords

References

  1. Cai, X. F., I. S. Lee, N. T. Dat, G. Shen and Y. H. Kim. 2004. Diterpenoid with inhibitory activity against NFAT transcription factor from Acanthopanax koreanum. Phytother. Res. 18, 677-680 https://doi.org/10.1002/ptr.1523
  2. Draves, A. H. and S. E. Walker. 2000. Determination of hypericin and pseudohypericin in pharmaceutical preparations by liquid chromatography with fluorescence detection. J. Chromatography 747, 57-66
  3. Felsenstein, J. 1993. PHYLIP (Phyogeny Inference Package) version 3.5s, Distributed by the author. Department of Genetics, Univ. of Washington, Seattle, USA
  4. Foster, S. 1996. Siberian Ginseng-Eleutherococcus senticosus. Botanical Booklet Series, No 302. Austin: American Botanical Council
  5. Glatthaar-Saalmuller, B., F. Sacher and A. Esperster. 2001. Antiviral activity of an extract derived from roots of Eleutherococcus senticosus. Antiviral Research 50, 223-228 https://doi.org/10.1016/S0166-3542(01)00143-7
  6. Gudzic, B., S. Dordevic, R. Palic and G. Stojanovic. 2001. Essential oils of Hypericum olympicum L. and Hypericum perforatum L. Flavour. Frangr. J. 16, 201-203 https://doi.org/10.1002/ffj.978
  7. Harkey, M. R., G. L. Herderson, M. E. Gershwin, J. S. Stern and R M. Hackman. 2001. Variability in commercial ginseng products: an analysis of 25 preparations. Am. J. Clin. Nur. 73, 1101-1106 https://doi.org/10.1093/ajcn/73.6.1101
  8. Huh, M. K. and H. W. Huh. 2005. Classification of genus Acanthopanax in Korea and genetic diversity using allozymes. Silva Genetica 54, 206-210 https://doi.org/10.1515/sg-2005-0030
  9. Jiao, S. D. 2003. Ten Lectures of the Use of Medicinals. pp. 711. Paradigm Publications, MA, USA
  10. Kim, Y. H., B. S. Chung and U. Sankawa. 1988. Pimaradine diterpenes from Acanthopanax koreanum. J. Nat. Prod. 51, 1080-1083 https://doi.org/10.1021/np50060a005
  11. Lee, Y. N. 1997. Flora of Korea. Kyo-Hak Publishing Co, Seoul, Korea
  12. Park, E. J., Y. Z. Zhao, Y. H. Kim, J. J. Lee and D. H. Sohn. 2004. Acanthoic acid from Acanthopanax koreanum protects against liver injury induced by tert-butyl hydroperoxide or carbon tetrachloride in vitro. Planta Med. 70, 321-327 https://doi.org/10.1055/s-2004-818943
  13. Petersen, I. L., K. E. Andersen, J. C. Sorensen and H. Sorensen. 2006. Determination of shikimate in crude plant extracts by micellar electrokinetic capillary chromatography. J. Chromatography 1130, 253-258 https://doi.org/10.1016/j.chroma.2006.08.011
  14. Takeshi, D., N. Sansei and N. Yoshisa. 2001. Constituents and pharmacological effects of Eucommia and Siberian ginseng. Acta Pharmacol. Sin. 22, 1057-1070