Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Choice of Thresholding Technique in Micro-CT Images of Trabecular Bone Does Not Influence the Prediction of Bone Volume Fraction and Apparent Modulus

  • Kim, Chi-Hyun (Department of Biomedical Engineering, Yonsei University) ;
  • Kim, Byung-Gwan (Department of Biomedical Engineering, Yonsei University) ;
  • Guo, X. Edward (Department of Biomedical Engineering, Columbia University)
  • Published : 2007.04.30
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Abstract

Trabecular bone can be accurately represented using image-based finite element modeling and analysis of these bone models is widely used to predict their mechanical properties. However, the choice of thresholding technique, a necessary step in converting grayscale images to finite element models which can thus significantly influence the structure of the resulting finite element model, is often overlooked. Therefore, we investigated the effects of thresholding techniques on micro-computed tomography (micro-CT) based finite element models of trabecular bone. Three types of thresholding techniques were applied to micro-CT images of trabecular bone which resulted in three unique finite element models for each specimen. Bone volume fractions and apparent moduli were predicted for each model and compared to experimental results. Our findings suggest that predictions of apparent properties agree well with experimental measurements regardless of the choice of thresholding technique in micro CT images of trabecular bone.

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References

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