Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
권호 표지

Effects of Ethanol Extract of Onion on the Lipid Profiles in Patients with Hypercholesterolemia

양파의 알코올 추출물이 고콜레스테롤혈증 환자의 지질 성상에 미치는 영향

  • Nam, Kyung-Hui (School of Public Health, Seoul National University) ;
  • Baik, Hyun-Wook (Department of Infernal Medicine, Boondang Jaesaeng General Hospital) ;
  • Choi, Tae-Youn (Department of Clinical Pathology, College of Medicine, Soonchunhyang University) ;
  • Yoon, Soon-Gyu (Department of Clinical Pathology, College of Medicine, Soonchunhyang University) ;
  • Park, Se-Won (Department of Molecular Biotechnology, Konkuk University) ;
  • Joung, Hyo-Jee (School of Public Health, Seoul National University)
  • 남경희 (서울대학교 보건대학원) ;
  • 백현욱 (분당제생병원 소화기내과) ;
  • 최태윤 (순천향대학교 의과대학 임상병리과학교실) ;
  • 윤순규 (순천향대학교 의과대학 임상병리과학교실) ;
  • 박세원 (건국대학교 분자생명공학과) ;
  • 정효지 (서울대학교 보건대학원)
  • Published : 2007.04.30
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Abstract

It is known that onion increases antioxidative and antibiotic capacity, and decreases blood pressure and cholesterol levels. The study was carried out to investigate whether ethanol extract of onion can enhance blood lipid profiles in hypercholesterolemic patients. Foully three hypercholesterolemic patients were randomly divided into 2 groups; 25 in controls and 18 in experimental group. The control group was offered to take placebo for 4 weeks (200 ml/day), and experimental group was offered to consume ethanol extract of onion for 8 weeks (200 ml/day that corresponds to 500 g of onion). There were no differences in sex, age, body mass index (BMI) and educational levels between groups before treatment. After 8 weeks of onion extract consumption, plasma triglycerides level was significantly decreased in experimental group compared to control (p<0.05). Total cholesterol level was tended to decrease in experimental group, but there was no significant difference of change between control and experimental group. The levels of plasma glucose and LDL-cholesterol were not changed significantly after onion extract consumption. In summary, alcohol extract of onion may have a positive effect on the lipid profiles of hypercholesterolemia patients through decreasing plasma triglyceride concentration.

Keywords

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