Journal of Chest Surgery

The Korean Society for Thoracic and Cardiovascular Surgery (대한심장혈관흉부외과학회)
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The Local Effect after Surgery in Non-small Cell Lung Cancer

비소세포성 폐암에서 수술 후의 국소 제어효과

  • Sa, Young-Jo (Department of Thoracic and Cardiovascular Surgery, St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Jeon, Hyun-Woo (Department of Thoracic and Cardiovascular Surgery, St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Lee, Sun-Hee (Department of Thoracic and Cardiovascular Surgery, St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Wang, Young-Pil (Department of Thoracic and Cardiovascular Surgery, Kangnam St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Park, Jae-Kil (Department of Thoracic and Cardiovascular Surgery, St. Mary's Hospital, The Catholic University of Korea College of Medicine)
  • 사영조 (가톨릭대학교 의과대학 성모병원 흉부외과학교실) ;
  • 전현우 (가톨릭대학교 의과대학 성모병원 흉부외과학교실) ;
  • 이선희 (가톨릭대학교 의과대학 성모병원 흉부외과학교실) ;
  • 왕영필 (가톨릭대학교 의과대학 강남성모병원 흉부외과학교실) ;
  • 박재길 (가톨릭대학교 의과대학 성모병원 흉부외과학교실)
  • Published : 2007.05.05
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Abstract

Background: Recent progress in the surgical therapy for lung cancer is one of the best examples of the successful evolution of clinical medicine. We reviewed our experience to evaluate the surgical outcomes in patients with non-small cell lung cancer. Material and Method: We reviewed clinical records of 432 consecutive patients with proven non-small cell lung cancer who underwent complete removal of the primary tumor together with hilar and mediastinal lymph nodes from 1995 to 2005. The clinical characteristics, surgical methods, and recurrence patterns were analyzed. Result: Lobectomy was the most common procedure (66.7%) performed and sleeve lobectomy was the least (5.6%). In 179 patients (42.6%) the recurrence was noted and the regional recurrence (67 cases, 16.0%) was less than systemic recurrence (112 cases, 26.7%). The main sites of regional recurrence were hilum (25 cases, 37.3%) and ipsilateral mediastinum (54/432 cases, 25.4%). The hospital mortality rate was 2.8% (12/432 cases) and resection-morbidity rate was 12.5% (54/432 cases). Conclusion: The low recurrence rate, especially regional recurrence rate indicated that our surgical procedures with preoperative measures were considered useful and effective.

배경: 암에 대한 수술적 치료의 치근의 발전은 임상적으로 가장 혁신적인 발전 중의 하나이다. 저자들은 비소세포성 폐암환자에서 시행한 수술적 치료의 효과를 검토해 보았다. 대상 및 방법: 1995년부터 2005년까지 저자들이 수술적 치험한 증례 중 완전 절제가 시행되었던 폐암환자 432예를 대상으로 하여 임상적 소견들과 수술방법 그리고 재발 양상 등에 대하여 분석하였다. 결과: 폐엽절제술이 가장 많이 시행되었으며(66.7%),소매 폐엽절제술(5.6%)이 가장 적게 시행되었다. 179예(42.6%)에서 관찰기간 중 재발이 확인되었으며, 국소 재발 예는 67예(16.0%)로서 전신적 재발 112예(26.7%)보다 현저히 작았다. 주된 국소 재발 부위는 폐문부(37.3%)와 동측 종격동(25.4%)이었으며, 병원 사망률은 2.8% (12/432예)였고 수술 유병률은 12.5% (52/432예)였다. 결론: 낮은 사망률과 국소 재발률을 얻었으며, 따라서 저자들의 수술적 치료방법은 안전하며 유효한 방법이라고 생각되었다.

Keywords

References

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