급성 열사병으로 폐사한 아프리카 사자의 병리조직학적 소견

Histopathological Findings of Sudden Death Caused by Acute Heat Stroke in an African Lion(Panthera leo)

  • 김규태 (대전동물원 동물병원) ;
  • 조성환 (충남대학교 수의과대학) ;
  • 손화영 (충남대학교 수의과대학) ;
  • 류시윤 (충남대학교 수의과대학)
  • Kim, Kyoo-Tae (Wild Animal Hospital, Daejeon Zoo Land) ;
  • Cho, Sung-Whan (College of Veterinary Medicine, Chungnam National University) ;
  • Son, Hwa-Young (College of Veterinary Medicine, Chungnam National University) ;
  • Ryu, Si-Yun (College of Veterinary Medicine, Chungnam National University)
  • 발행 : 2007.03.30

초록

Heat stroke can lead multi-organ damage with hemorrhage and necrosis in the lungs, heart, liver, kidneys, brain and Ut. Heat stroke occurs when the elevation of core body temperatures induce a failure of thermoregulatory mechanism. A four-year-old male African Lion(Panthera leo) showed clinical signs such as panting, tachycardia, hyperthermia, unconsciousness and mydriasis under He hish humidity and hot weather. Clinical treatment and pouring cool water was unsuccessful. Grossly, congestion of lungs and pleura was observed. Yellowish discoloration was observed in the renal cortex. Microscopically, the coagulative necrosis in kidney and congestion of lungs and spleen were observed. In our knowledge, this case was closely associated with acute heat stroke.

키워드

참고문헌

  1. Bouchama A, Roberts G, Al Mohanna F, El-Sayed R, Lach B, Chollet-Martin S, Ollivier V, Al Baradei R, Loualich A, Nakeeb S, Eldali A, de Prost D. Inflammatory, hemostatic, and clinical changes in a baboon experimental model for heatstroke. J Appl Physiol 2005; 98: 697-705 https://doi.org/10.1152/japplphysiol.00461.2004
  2. Broessner G. Beer R. Franz G. Lackner P. Engelhardt K. Brenneis C. Pfausler B. Schmutzhard E. Case report: severe heat stroke with multiple organ dysfunction - a novel intravascular treatment approach Crit Care 2005: 9: R498-501
  3. Bruchim Y, Klement E, Saragusty J, Finkeilstein E, Kass P, Aroch I. Heat stroke in dogs: a retrospective study of 54 cases(1999-2004) and analysis of risk factors for death. J Vet Int Med 2006; 20: 38-46
  4. Oamanhouri ZA, Tayeb OS. Animal models for heat stroke studies. Pharmacol Toxicol Methods 1992; 28: 119-127 https://doi.org/10.1016/1056-8719(92)90073-A
  5. Deshpande GG. Heidemann SM. Sarnaik AP. Heat stress is associated with decreased lactic acidemia in rat sepsis. Crit Care 2000; 4: 45-49 https://doi.org/10.1186/cc649
  6. Drew ML. The use of a tympanic membrane thermometer for assessing hyperthermia in bighorn sheep. J Wildl Dis 1996: 32: 512-516 https://doi.org/10.7589/0090-3558-32.3.512
  7. Fenoglio JJ, Irey NS. Myocardial changes in malignant hyperthermia. Am J Pathol 1977; 89: 51-58
  8. Finocchiaro R, van Kaam JBCHM, Protolano B, Misztal I Eft능ct of heat stress on production of Mediterranean dairy sheep. J Dairy Sci 2005; 88: Finocchiaro R, van Kaam JBCHM, Protolano B, Misztal I Effect of heat stress on production of Mediterranean dairy sheep. J Dairy Sci 2005; 88: 1855-1864 https://doi.org/10.3168/jds.S0022-0302(05)72860-5
  9. Grogan H, Hopkins PM. Heat stroke: implications for critical care and anesthesia. Br J Anesth 2002; 88: 700-707 https://doi.org/10.1093/bja/88.5.700
  10. Joslin JO. Other primates excluding great ape. In: Zoo and Wild Animal Medicine, 5th ed. St. Louis: Saunders. 2003: 346-381
  11. Ringler DJ. Inflammation and repair. In: Veterinary Pathology. 6th ed. Baltimore: Williams & Wilkins. 1997: 156-157
  12. Varghese GM, John G, Thomas K, Abraham OC, Mathai D. Predictors of multi-organ dysfunction in heatstroke. Emerg Med J 2005; 22: 185-187 https://doi.org/10.1136/emj.2003.009365
  13. Wack RF. Felidae. In: Zoo and Wild Animal Medicine. 5th ed. St. Louis: Saunders. 2003: 491-501
  14. 김상근.김주헌. 김천호. 나승렬. 박전홍. 양일석. 유창준. 윤영원. 이상천. 이장헌. 이호일. 한호재. 가축생리학. 서울: 광일문화사. 1996: 383-396