Imaging Science in Dentistry
- 제37권1호
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- Pages.27-33
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- 2007
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- 2233-7822(pISSN)
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- 2233-7830(eISSN)
골형태분석법과 micro-CT를 이용한 골소주 특성에 대한 연구
Study of bony trabecular characteristics using bone morphometry and micro-CT
- 송영한 (원광대학교 치과대학 구강악안면방사선학교실) ;
- 이완 (원광대학교 치과대학 구강악안면방사선학교실) ;
- 이창진 (원광대학교 치과대학 구강악안면방사선학교실) ;
- 지정현 (원광대학교 치과대학 구강악안면방사선학교실) ;
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이병도
(원광대학교 치과대학 구강악안면방사선학교실)
- Song, Young-Han (Department of Oral & Maxillofacial Radiology, School of Dentistry, Wonkwang University) ;
- Lee, Wan (Department of Oral & Maxillofacial Radiology, School of Dentistry, Wonkwang University) ;
- Lee, Chang-Jin (Department of Oral & Maxillofacial Radiology, School of Dentistry, Wonkwang University) ;
- Ji, Jung-Hyun (Department of Oral & Maxillofacial Radiology, School of Dentistry, Wonkwang University) ;
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Lee, Byung-Do
(Department of Oral & Maxillofacial Radiology, School of Dentistry, Wonkwang University)
- 발행 : 2007.03.31
초록
Purpose : The research was done to investigate the effectiveness of 2D bony morphometry and microstructure of micro-computed tomography (micro-CT) on the osteoporotic bony change. We performed the bone morphometric analysis of proximal femur in ovariectomized rabbits with BMD and micro-CT examination. Materials and Methods : Twenty-one female (Newzealand, about 16 weeks old, 2.9-3.4kg) rabbits were used. Three rabbits were sacrificed on the day when experiment began (Baseline). The remaining 18 rabbits were divided into two groups. One group was ovariectomized bilaterally (OVX) and the other animals were subjected to sham operation (Sham). Bone specimens were obtained from the right and left femur of sacrificed rabbits. At intervals of 1, 2, 3, 5, 6 months respectively, BMD tests were performed on the proximal femur by using PIXlmus 2 (GE Lunar Co. USA), 2-dimensional bone morphometric analysis by custome computer program and 2D/3D bone structure analysis by micro-CT (Skyscan 1072, Antwerpen, Belgium). Statistical analysis was carried out for the correlation between bone morphometry, micro-CT and BMD Result : BV/TV, Tb.Th, Tb.N of micro-CT parameters showed higher values in sham group than OVX group. N.Nd/Ar.RI, N.NdNd, N.NdTm, N. TmTm, PmB/Ar.RI, 3-D BoxSlope of 2D morphometric parameters showed higher values in Sham group than OVX group. The micro-CT parameters of Tb.Sp, Tb.N were statistically significant correlated with BMD respectively. Several 2D morphometric parameters were statistically significant correlated with BMD respectively. Conclusion : Several parameters of 2D bony morphometry and micro-CT showed effective aspects on the osteoporotic bony change.