4가지 한방 소재(행인, 호장근, 자초, 강황)의 화장품약리활성에 관한 연구

Study on Cosmeceutical Activity of four Kinds of Korea Herb Medicine Materials

  • 김영훈 (대구한의대학교 화장품약리학과) ;
  • 이수미 (대구한의대학교 화장품약리학과) ;
  • 천순주 (대구한의대학교 화장품약리학과) ;
  • 장민정 (대구한의대학교 화장품약리학과) ;
  • 전동하 (대구한의대학교 화장품약리학과) ;
  • 최향자 (소리소) ;
  • 조우아 (남부대학교 향장미술학부) ;
  • 이진태 (대구한의대학교 화장품약리학과)
  • Kim, Youngh-Hun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Su-Mi (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Cheon, Soon-Ju (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Jang, Min-Jung (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Jun, Dong-Ha (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Choi, Hyang-Ja (Soriso) ;
  • Cho, Woo-A (Department of Cosmetic Science, Nambu University) ;
  • Lee, Jin-Tae (Department of Cosmeceutical Science, Daegu Haany University)
  • 발행 : 2007.12.30

초록

The aim of this study was to assess the cosmeceutical activies of four kinds of Korea herb medicine extracts using in cosmetics and related industries. The cosmeceutical activities of extracts were investigated by tyrosinase inhibition, astringent, anti-bacterial and MTT assay for cell viability. In the whitening effect, PA that the highest tyrosinase inhibition activity showed 56% at 10 ppm in ethanol extract. Also water and ethanol extract of RE showed 54%, 68% at 1,000 ppm, respectively, but LE and CA showed lower effect. Astringent effect of water and ethanol extract of PA appeared over 60% at 1,000ppm concentration but other extracts showed no astringent effect. In the anti-bacterial test, water and ethanol extract of PA showed no anti-bacterial effect against all microorganisms. But water and ethanol extract of RE showed anti-bacterial effect on Staphylococcus aureus, ethanol extract of showed on Staphylococcus aureus and Propionibacterium acnes, ethanol extract of CA showed on Candida albicans. The resUlt of stability test showed that the emulsion of containing PA were very stable at various temperature and sun-light test. Viscosity and pH of emulsion did not change. From the results of human patch test to assess the safety of cosmetics containing PA there was no negative reaction on skin was found.

키워드