Conjugated Linoleic Acid in Korean Mothers' Milk and Infant Formula

한국인 모유와 조제분유 중의 공액리놀레산

  • Park, Cherl-Woo (HK Biotech Co., Ltd.) ;
  • Bahn, Kyeong-Nyeo (Busan Regional Korea Food & Drug Administration) ;
  • Lee, Young-Nam (HK Biotech Co., Ltd.) ;
  • Kim, Jeong-Ok (HK Biotech Co., Ltd.) ;
  • Kim, Min-Seok (Division of Applied Life Science and Institute of Agricultural and Life Science, Gyeongsang National University) ;
  • Ha, Yeong-Lae (Division of Applied Life Science and Institute of Agricultural and Life Science, Gyeongsang National University)
  • 박철우 ((주)HK 바이오텍) ;
  • 반경녀 (부산지방식품의약품안전청) ;
  • 이영남 ((주)HK 바이오텍) ;
  • 김정옥 ((주)HK 바이오텍) ;
  • 김민석 (경상대학교 응용생명학부, 농업생명과학연구원) ;
  • 하영래 (경상대학교 응용생명학부, 농업생명과학연구원)
  • Published : 2007.03.31


The concentrations of conjugated linoleic acid (CLA) in twelve Korean mothers' milk samples collected in October 2006 and four infant formula samples produced by Korean manufacturers were determined. CLA detected from both mothers' milk and infant formula samples was only cis-9, trans-11 CLA isomer. The amount of cis-9, trans-11 CLA in Korean mothers' milk (100 mL) ranged from 4.32 to 10.12 mg ($6.27{\pm}0.28\;mg$). Infant formula (13 g), which is the manufacturers' recommended amount to make up 100 mL with water, contained cis-9, trans-11 CLA isomer in amounts ranging from 1.61 to 2.97 mg ($2.27{\pm}0.31\;mg$).

한국인 모유에는 cis-9, trans-11 CLA 이성체만 동정되었고, 그 함량은 $4.32{\sim}10.12\;mg/100\;mL$(평균 $6.27{\pm}0.28\;mg/100\;mL$)이었고, 지방함량 중에는 $1.35{\sim}3.13\;mg/g$(평균 $1.96{\pm}0.06\;mg/g$)으로 개인에 따라 큰 차이가 있었다. 한국인 모유에 함유된 CLA의 함량은 외국의 CLA 함량에 비해 낮았고, 그 이유는 식사의 차이 때문인 것으로 추정되었다. 국내에서 제조된 조제분유에서도 cis-9, trans-11 CLA만 동정되었는데, 그 함량은 $2.35{\sim}22.82\;mg/100\;g$으로 평균치는 $17.45{\pm}1.24\;mg/100\;g$이었고, 지방에 함유된 cis-9, trans-11 CLA 함량은 $0.45\;mg/g{\sim}0.85\;mg/g$으로 그 평균치는 $0.65{\pm}0.02\;mg/g$이었다. 영유아가 조제분유 제조사의 지시된 13% 조제분유를 섭취할 경우 cis-9, trans-11 CLA를 2.27 mg 섭취하는 것으로 모유 100 mL에 함유되어 있는 양에 비해 낮다. 따라서 조제분유를 조제할 때 모유와 동일한 cis-9, trans-11 CLA를 섭취할 수 있도록 조제분유를 제조하는 것이 바람직하다.



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