Acknowledgement
Supported by : Korea Research Foundation, Korean Ministry of Science and Technology
References
- Adams, J. M. and Cory, S. (1998) The Bcl-2 protein family: arbiters of cell survival 1. Science 281, 1322-1326 https://doi.org/10.1126/science.281.5381.1322
- Banerjee, S., Zhang, Y., Ali, S., Bhuiyan, M., Wang, Z., et al. (2005) Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer. Cancer Res. 65, 9064-9072 https://doi.org/10.1158/0008-5472.CAN-05-1330
- Boege, F., Staub, T., Kehr, A., Boesenberg, C., Christiansen, K., et al. (1996) Selected novel flavonoids inhibit the DNA topoisomerase I. J. Biol. Chem. 271, 2262-2270 https://doi.org/10.1074/jbc.271.4.2262
- Brown, K. (2002) Breast cancer chemoprevention: risk-benefit effects of the antioestrogen tamoxifen. Expert Opin. Drug Saf. 1, 253-267 https://doi.org/10.1517/14740338.1.3.253
- Chan, K. and Morris, G. J. (2006) Chemoprevention of breast cancer for women at high risk. Semin. Oncol. 33, 642-646
- Chen, Y. R., Meyer, C. F., and Tan, T. H. (1996) Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation- induced apoptosis. J. Biol. Chem. 271, 631-634 https://doi.org/10.1074/jbc.271.2.631
- Cholbi, M. R., Paya, M., and Alcaraz, M. J. (1991) Inhibitory effects of phenolic compounds on CCl4-induced microsomal lipid peroxidation. Experientia 47, 195-199 https://doi.org/10.1007/BF02041265
- Corbiere, C., Liagre, B., Terro, F., and Beneytout, J. L. (2004) Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells. Cell Res. 14, 188-196 https://doi.org/10.1038/sj.cr.7290219
- Cryns, V. and Yuan, J. (1998) Proteases to die for. Genes Dev. 12, 1551-1570 https://doi.org/10.1101/gad.12.11.1551
- Ding, W. X., Shen, H. M., and Ong, C. N. (2000) Critical role of reactive oxygen species and mitochondrial permeability transition in microcystin-induced rapid apoptosis in rat hepatocytes. Hepatology 32, 547-555 https://doi.org/10.1053/jhep.2000.16183
- Doostdar, H., Burke, M. D., and Mayer, R. T. (2000) Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYPIA and CYP1B1. Toxicology 144, 31-38 https://doi.org/10.1016/S0300-483X(99)00215-2
- Duthie, S. J. and Dobson, V. L. (1999) Dietary flavonoids protect human colonocyte DNA from oxidative attract in vivo. Eur. J. Nutr. 38, 28-34 https://doi.org/10.1007/s003940050043
- Fan, Y., Chen, H., Qiao, B., Luo, L., Ma, H., et al. (2007) Opposing effects of ERK and p38 MAP kinases on HeLa cell apoptosis induced by dipyrithione. Mol. Cells 23, 30-38
- Gerritsen, M. E. (1998) Inhibitors of cytokine induced gene expression. Adv. Exp. Med. Biol. 439, 183-190
- Gianinazzi, C., Grandgirard, D., Imboden, H., Egger, L., Meli, D. N., et al. (2003) Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis. Acta Neuropathol. 105, 499-507
- Green, D. R. and Reed, J. C. (1998) Mitochondria and apoptosis. Science 281, 1309-1312 https://doi.org/10.1126/science.281.5381.1309
- Grivicich, I., Regner, A., da Rocha, A. B., Grass, L. B., Alves, P. A., et al. (2005) Irinotecan/5-fluorouracil combination induces alterations in mitochondrial membrane potential and caspases on colon cancer cell lines. Oncol. Res. 15, 385-392 https://doi.org/10.3727/096504005776449680
- Hsu, Y. L., Kuo, P. L., Liu, C. F., and Lin, C. C. (2004) Acacetin- induced cell cycle arrest and apoptosis in human nonsmall cell lung cancer A549 cells. Cancer Lett. 212, 53-60 https://doi.org/10.1016/j.canlet.2004.02.019
- Hu, C. A., Tang, C. A., and Wang, J. (2001) Caspase activation in response to cytotoxic Rena catesbeiana ribonuclease in MCF-7 cells. FEBS Lett. 503, 65-68 https://doi.org/10.1016/S0014-5793(01)02691-6
- Jacobson, M. D. and Raff, M. C. (1995) Programmed cell death and Bcl-2 protection in very low oxygen. Nature 374, 814-816 https://doi.org/10.1038/374814a0
- Jacobson, M. D., Burne, J. F., and Raff, M. C. (1994) Mechanisms of programmed cell death and Bcl-2 protection. Biochem. Soc. Trans. 22, 600-602 https://doi.org/10.1042/bst0220600
- Janicke, R. U., Sprengart, M. L., Wati, M. R., and Porter, A. G. (1998) Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J. Biol. Chem. 273, 9357-9360 https://doi.org/10.1074/jbc.273.16.9357
- Jenal, A., Thomas, A., Murry, T., and Thun, M. (2002) Cancer stastics, 2002. CA Cancer J. Clin. 52, 23-37 https://doi.org/10.3322/canjclin.52.1.23
- Johnson, G. L. and Lapadat, R. (2002) Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298, 1911-1912 https://doi.org/10.1126/science.1072682
- Johnston, S. R. (1997) Acquired tamoxifen resistance in human breast cancer--potential mechanisms and clinical implications. Anticancer Drugs 8, 911-930 https://doi.org/10.1097/00001813-199711000-00002
- Kallio, A., Zheng, A., Dahllund, J., Heiskanen, K. M., and Harkonen, P. (2005) Role of mitochondria in tamoxifen-induced rapid death of MCF-7 breast cancer cells. Apoptosis 10, 1395-1410
- Kanno, S., Tomizawa, A., Ohtake, T., Koiwai, K., Ujibe, M., et al. (2006) Naringenin-induced apoptosis via activation of NF-kappaB and necrosis involving the loss of ATP in human promyeloleukemia HL-60 cells. Toxicol Lett. 166, 131-139 https://doi.org/10.1016/j.toxlet.2006.06.005
- Kato, S., Endoh, H., Masuhiro, Y., Kitamoto, T., Uchiyama, S., et al. (1995) Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270, 1491-1494
- Kraft, C., Jenett-Siems, K., Siems, K., Jakupovic, J., Mavi, S., et al. (2003) In vitro antiplasmodial evaluation of medicinal plants from Zimbabwe. Phytother. Res. 17, 123-128 https://doi.org/10.1002/ptr.1066
- Lu, G., Liao, J., Yang, G., Reuhl, K. R., Hao, X., et al. (2006) Inhibition of adenoma progression to adenocarcinoma in a 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model in A/J mice by tea polyphenols and caffeine. Cancer Res. 66, 1494-1501
- Lupu, R., Cardillo, M., Cho, C., Harris, L., Hijazi, M., et al. (1996) The significance of heregulin in breast cancer tumor progression and drug resistance. Breast Cancer Res. Treat. 38, 57-66 https://doi.org/10.1007/BF01803784
- Matsura, T., Kai, M., Fujii, Y., Ito, H., and Yamada, K. (1999) Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation. Free Radic. Res. 30, 73-83 https://doi.org/10.1080/10715769900300081
- Middleton, E., Kandaswami, C., and Theoharides, T. C. (2000) The effect of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol. Rev. 52, 673-751
- Minden, A. and Karin, M. (1997) Regulation and function of the JNK subgroup of MAP kinases. Biochim. Biophy. Acta 1333, F85-F105
- Mohammad, R. M., Banerjee, S., Li, Y., Aboukameel, A., Kucuk, O., et al. (2006) Cispain-induced antitumor activity is potentiated by the soy isoflavone genistein in BxPC-3 pancreatic tumor xenografts. Cancer 106, 1260-1268 https://doi.org/10.1002/cncr.21731
- Pan, M. H., Lai, C. S., Hsu, P. C., and Wang, Y. J. (2005) Acacetin induces apoptosis in human gastric carcinoma cells accompanied by activation of caspase cascades and production of reactive oxygen species. J. Agric. Food Chem. 53, 620-630 https://doi.org/10.1021/jf048430m
- Pan, M. H., Lai, C. S., Wang, Y. J., and Ho, C. T. (2006) Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice. Biochem. Pharmacol. 72, 1293-303 https://doi.org/10.1016/j.bcp.2006.07.039
- Plaumann, B., Fritsche, M., Rimpler, H., Brandner, G., and Hess, R. D. (1996) flavonoids activate wild-type p53. Oncogene 13, 1605-1614
- Raingeaud, J., Gupta, S., Rogers, J. S., Dicken, M., Han, J., et al. (1995) Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270, 7420-7426
- Rao, L. and White, E. (1997) Bcl-2 and the ICE family of apoptotic regulators: making connection. Curr. Opin. Genet. Dev. 7, 52-58 https://doi.org/10.1016/S0959-437X(97)80109-8
- Schrivastava, A., Tiwari, M., Sinha, R. A., Kumar, A., Balapure, A. K., et al. (2006) Molecular iodine induces caspaseindependent apoptosis in human breast carcinoma cells involving mitochondria-mediated pathway. J. Biol. Chem. 281, 19762-19771 https://doi.org/10.1074/jbc.M600746200
- Singh, R. P., Agrawal, P., Yim, D., Agarwal, C., and Agarwal, R. (2005) Acacetin inhibits cell growth and cell cycle progression, and induces apoptosis in human prostate cancer cells: structure-activity relationship with linarin and linarin acetate. Carcinogenesis 26, 845-54 https://doi.org/10.1093/carcin/bgi014
- Smith, L. L., Brown, K., Carthew, P., Lim, C. K., Martin, E. A., et al. (2000) Chemoprevention of breast cancer by tamoxifen: risks and opportunities. Crit. Rev. Toxicol. 30, 571-594 https://doi.org/10.1080/10408440008951120
- Susin, S. A., Lorenzo, H. K., Zamzami, N., Marzo, I., Snow, B. E., et al. (1999) Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397, 441-446 https://doi.org/10.1038/17135
- Tsujimoto, Y. (1998) Role of Bcl-2 family proteins in apoptosis: apoptosomes or mitichondria? Genes Cells 3, 697-707 https://doi.org/10.1046/j.1365-2443.1998.00223.x
- Twiddy, D., Cohen, G. M., MacFarlane, M., and Cain, K. (2006) Caspase 7 is directly activated by the -700 kDa apoptosome complex and is released as a stable XIAP-caspase 7-200 kDa complex. J. Biol. Chem. 281, 3876-3888 https://doi.org/10.1074/jbc.M507393200
- Yim, S. H., Kim, H. J., and Lee, I. S. (2003) A polyacetylene and flavonoids from Cirsium rhinoceros. Arch. Pharm. Res. 26, 128-131 https://doi.org/10.1007/BF02976657
- Zhang, K., Yang, E. B., Tang, W. Y., Wong, K. P., and Mack, P. (1997) Inhibition of glutathione reductase by plant polyphenols. Biochem. Pharmacol. 54, 1047-1053 https://doi.org/10.1016/S0006-2952(97)00315-8
- Zheng, T. S., Schlosser, S. F., Dao, T., Hingorani, R., Crispe, I. N., et al. (1998) Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo. Proc. Natl. Acad. Sci. USA 95, 13618-13623