Acknowledgement
Supported by : Korea Science and Engineering Foundation (KOSEF)
References
- Alfandari, D., Cousin, H., Gaultier, A., Smith, K., White, J. M., et al. (2001) Xenopus ADAM 13 is a metalloprotease required for cranial neural crest-cell migration. Curr. Biol. 11, 918-930 https://doi.org/10.1016/S0960-9822(01)00263-9
- Artavanis-Tsakonas, S., Rand, M. D., and Lake, R.J. (1999) Notch signaling: cell fate control and signal integration in development. Science 284, 770-776 https://doi.org/10.1126/science.284.5415.770
- Bang, O. S., Kim, E. J., Chung, J. G., Lee, S. R., Park, T. K., et al. (2000) Association of focal adhesion kinase with fibronectin and paxillin is required for precartilage condensation of chick mesenchymal cells. Biochem. Biophys. Res. Commun. 278, 522-529 https://doi.org/10.1006/bbrc.2000.3831
- Beverly, L. J., Felsher, D. W., and Capobianco, A. J. (2005) Suppression of p53 by Notch in lymphomagenesis: implications for initiation and regression. Cancer Res. 65, 7159-7168 https://doi.org/10.1158/0008-5472.CAN-05-1664
- Bianchi, S., Dotti, M. T., and Federico, A. (2006) Physiology and pathology of notch signalling system. J. Cell Physiol. 207, 300-308 https://doi.org/10.1002/jcp.20542
- Bland, C. E., Kimberly, P., and Rand, M. D. (2003) Notch-induced proteolysis and nuclear localization of the Delta ligand. J. Biol. Chem. 278, 13607-13610 https://doi.org/10.1074/jbc.C300016200
- Buxbaum, J. D., Liu, K. N., Luo, Y., Slack, J. L., Stocking, K. L., et al. (1998) Evidence that tumor necrosis factor alpha converting enzyme is involved inregulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor. J. Biol. Chem. 273, 27765-27767 https://doi.org/10.1074/jbc.273.43.27765
- Chang, S. C., Hoang, B., Thomas, J. T., Vukicevic, S., Luyten, F. P., et al. (1994). Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development. J. Biol. Chem. 269, 28227-28234
- Del Castillo, G., Murillo, M. M., Alvarez-Barrientos, A., Bertran, E., Fernandez, M., et al. (2006) Autocrine production of TGFbeta confers resistance to apoptosis after an epithelial-mesenchymal transition process in hepatocytes, Role of EGF receptor ligands. Exp. Cell Res. 312, 2860-2871 https://doi.org/10.1016/j.yexcr.2006.05.017
- DeLise, A. M., Fischer, L., and Tuan, R. S. (2000) Cellular interactions and signaling in cartilage development. Osteoarthritis Cartilage 8, 309-334 https://doi.org/10.1053/joca.1999.0306
- Denker, A. E., Haas, A. R., Nicoll, S. B., and Tuan, R. S. (1999) Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: I. Stimulation by bone morphogenetic protein-2 in high-density micromass cultures. Differentiation 64, 67-76 https://doi.org/10.1046/j.1432-0436.1999.6420067.x
- Denker, A. E., Nicoll, S. B., and Tuan, R. S. (1995) Formation of cartilage-like spheroids by micromass cultures of murine C3H10T1/2 cells upon treatment with transforming growth factor-beta 1. Differentiation 59, 25-34 https://doi.org/10.1046/j.1432-0436.1995.5910025.x
- Elford, P. R., Graeber, M., Ohtsu, H., Aeberhard, M., Legendre, B., et al. (1992) Induction of swelling, synovial hyperplasia and cartilage proteoglycan loss upon intra-articular injection of transforming growth factor beta-2 in the rabbit. Cytokine 4, 232-238 https://doi.org/10.1016/1043-4666(92)90061-U
- Fambrough, D., Pan, D., Rubin, G. M., and Goodman, C. S. (1996). The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila. Proc. Natl. Acad. Sci. USA 93, 13233-13238
- Fox, J. W. and Bjarnason, J. B. (1996) The reprolysins, a family of metalloproteinases defined by snake venom and mammalian metalloproteinases; in: Zinc Metalloproteases in Health and Disease, Hooper, N. M. (ed.), pp. 47-82, Taylor & Francis
- Goessler, U. R., Bugert, P., Bieback, K., Deml, M., and Sadick, H. (2005) In-vitro analysis of the expression of TGFbeta-superfamily- members during chondrogenic differentiation of mesenchymal stem cells and chondrocytes during dedifferentiation in cell culture. Cell. Mole. Bio. Lett. 10, 345-362
- Goessler, U. R., Bugert, P., Bieback, K., Sadick, H., Baisch, A., et al. (2006) In vitro analysis of differential expression of collagens, integrins, and growth factors in cultured human chondrocytes. Otolaryngol. Head Neck Surg. 134, 510-515 https://doi.org/10.1016/j.otohns.2005.10.026
- Gotz, W., Duhr, S., and Jager, A. (2005) Distribution of components of the insulin-like growth factor system in the temporomandibular joint of the aging mouse. Growth Dev. Aging 69, 67-79
- Hall, R. J. and Erickson, C. A. (2003) ADAM 10: an active metalloprotease expressed during avian epithelial morphogenesis. Dev. Biol. 256, 146-159
- Hartmann, D., de Strooper, B., Serneels, L., and Craessaerts, K. (2002) The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts. Hum. Mol. Genet. 11, 2615-2624 https://doi.org/10.1093/hmg/11.21.2615
- Hassel, J. R. and Horigan, E. A. (1982) Chondrogenesis: a model developmental system for measuring teratogenic potential of compounds. Teratogenesis Carcinog. Mutagen. 2, 325-331 https://doi.org/10.1002/1520-6866(1990)2:3/4<325::AID-TCM1770020314>3.0.CO;2-1
- Hattori, M., Osterfield, M., and Flanagan, J. G. (2000) Regulated cleavage of a contact-mediated axon repellent. Science 289, 1360-1365 https://doi.org/10.1126/science.289.5483.1360
- Huovila, A. P., Turner, A. J., Pelto-Huikko, M., Karkkainen, I., and Ortiz, R. M. (2005) Shedding light on ADAM metalloproteinases. Trends Biochem. Sci. 30, 413-422 https://doi.org/10.1016/j.tibs.2005.05.006
- Jin, E-J., Park, J. H., Lee, S. Y., Chun, J. S., Bang, O. S., et al. (2006a) Wnt-5a is involved in TGF-beta3-stimulated chondrogenic differentiation of chick wing bud mesenchymal cells. Int. J. Biochem. Cell Biol. 38, 183-195 https://doi.org/10.1016/j.biocel.2005.08.013
- Jin, E-J., Lee, S. Y., Choi, T. A., Jung, J. C., Bang, O. S., et al. (2006b) BMP-2-enhanced chondrogenesis involves p38 MAPK-mediated down-regulation of Wnt-7a pathway. Mol. Cells 22, 353-359
-
Jin, E-J., Lee, S. Y., Jung, J. C., Bang, O. S., and Kang, S. S. (2007) TGF-
${\beta}3$ inhibits chondrogenesis of cultured chick leg bud mesenchymal cells via downregulation of connexin 43 and integrin -${\beta}4$ . J. Cell. Physiol. (in press) - Kaartinen, V., Voncken, J. W., and Shuler, C. (1995) Abnormal lung development and cleft palate in mice lacking TGF-beta3 indicates defects of epithelial-mesenchymal interaction. Nat. Genet. 11, 415-421 https://doi.org/10.1038/ng1295-415
- Karsenty, G. (1998) Transcriptional regulation of osteoblast differentiation during development. Front. Biosci. 3, d834-d837 https://doi.org/10.2741/A326
- Knudson, C. B. and Knudson, W. (2001) Cartilage proteoglycans. Semin. Cell Dev. Biol. 12, 69-78
- LaVoie, M. J. and Selkoe, D. J. (2003) The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments. J. Biol. Chem. 278, 34427-34437 https://doi.org/10.1074/jbc.M302659200
- Lev, R. and Spicer, S. S. (1964) Specific staining of sulfate groups with alcian blue at low pH. J. Histochem. Cyctochem. 12, 309 https://doi.org/10.1177/12.4.309
- Lieber, T., Kidd, S., and Young, M. W. (2002) kuzbanian-mediated cleavage of Drosophila Notch. Genes Dev. 2002 16, 209-221 https://doi.org/10.1101/gad.942302
- Louvi, A. and Artavanis-Tsakonas, S. (2006) Notch signalling in vertebrate neural development. Nat. Rev. Neurosci. 7, 93-102 https://doi.org/10.1038/nrn1847
- Lyons, R. M. and Moses, H. L. (1990) Transforming growth factors and the regulation of cell proliferation. Eur. J. Biochem. 187, 467-473 https://doi.org/10.1111/j.1432-1033.1990.tb15327.x
- Maleski, M. P. and Knudson, C. B. (1996) Hyaluronan-mediated aggregation of limb bud mesenchyme and mesenchymal condensation during chondrogenesis. Exp. Cell. Res. 225, 55-66 https://doi.org/10.1006/excr.1996.0156
- Massague, J. (1987) The TGF-beta family of growth and differentiation factors. Cell 49, 437-438 https://doi.org/10.1016/0092-8674(87)90443-0
- Massicotte, F., Fernandes, J. C., Martel-Pelletier, J., Pelletier, J. P., and Lajeunesse, D. (2006) Modulation of insulin-like growth factor 1 levels in human osteoarthritic subchondral bone osteoblasts. Bone 38, 333-341 https://doi.org/10.1016/j.bone.2005.09.007
- Muraoka, R. S., Dumont, N., Ritter, C. A., Dugger, T. C., Brantley, D. M., et al. (2002) Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases. J. Clin. Invest. 109, 1551-1559 https://doi.org/10.1172/JCI0215234
- Nickoloff, B. J., Osborne, B. A., and Miele, L. (2003) Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. Oncogene 22, 6598-6608 https://doi.org/10.1038/sj.onc.1206758
- Niswander, L. and Martin, G. R. (1993) FGF-4 and BMP-2 have opposite effects on limb growth. Nature 361, 68-71 https://doi.org/10.1038/361068a0
- Pan, D. and Rubin, G. M. (1997) Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis. Cell 90, 271-280 https://doi.org/10.1016/S0092-8674(00)80335-9
- Proetzel, G., Pawlowski, S. A., Wiles, M. V., Yin, M., Boivin, G. P., et al. (1995) Transforming growth factor-beta 3 is required for secondary palate fusion. Nat. Genet. 11, 409-414 https://doi.org/10.1038/ng1295-409
- Qi, H., Rand, M. D., Wu, X., Sestan, N., Wang, W., et al. (1999) Processing of the notch ligand delta by the metalloprotease Kuzbanian. Science 283, 91-94 https://doi.org/10.1126/science.283.5398.91
- Reddi, A. H. (1981) Cell biology and biochemistry of endochondral bone development. Collagen Relat. Res. 1, 209-226 https://doi.org/10.1016/S0174-173X(81)80021-0
- Sampath, T. K., Maliakal, J. C., Hanschka, P. V., Jones, W. K., Sasak, H., et al. (1992) Recombinant human osteogenic protein (OP-1) induces new bone formation in vivo with specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro. J. Biol. Chem. 267, 20352-20362
- Sanford, L. P., Ormsby, I., Gittenberger-de Groot, A. C., Sariola, H., Friedman, R., et al. (1997) TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes. Development 124, 2659-2670
- Seals, D. F. and Courtneidge, S. A. (2003) The ADAMs family of metalloproteases: multidomain proteins with multiple functions. Genes. Dev. 17, 7-30 https://doi.org/10.1101/gad.1039703
- Shakibaei, M. and Merker, H. J. (1999) Beta1-integrins in the cartilage matrix. Cell Tissue Res. 296, 565-573 https://doi.org/10.1007/s004410051318
- Shi, W., Heisterkamp, N., Groffen, J., Zhao, J., Warburton, D., et al. (1999) TGF-beta3-null mutation does not abrogate fetal lung maturation in vivo by glucocorticoids. Am. J. Physiol. 277, L1205-L1213
- Shull, M. M., Ormsby, I., Kier, A. B., Pawlowski, S., Diebold, R. J., et al. (1992) Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 359, 693-699 https://doi.org/10.1038/359693a0
- Six, E., Ndiaye, D., Laabi, Y., Brou, C., Gupta-Rossi, N., et al. (2003) The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase. Proc. Natl. Acad. Sci. USA 100, 7638-7643
- Skovronsky, D. M., Moore, D. B., Milla, M. E., Doms, R. W., and Lee, V. M. (2000) Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network. J. Biol. Chem. 275, 2568-2575 https://doi.org/10.1074/jbc.275.4.2568
- Vasiliauskas, D., Laufer, E., and Stern, C. D. (2003) A role for hairy1 in regulating chick limb bud growth. Dev. Biol. 262, 94-106 https://doi.org/10.1016/S0012-1606(03)00360-9
- Watanabe, N., Tezuka, Y., Matsuno, K., Miyatani, S., Morimura, N., et al. (2003) Suppression of differentiation and proliferation of early chondrogenic cells by Notch. J. Bone Miner. Metab. 21, 344-352 https://doi.org/10.1007/s00774-003-0428-4
- Weinmaster, G. (1997) The ins and outs of Notch signaling, Mol. Cell. Neurosci. 9, 91-102 https://doi.org/10.1006/mcne.1997.0612
- Wolfsberg, T. G. and White, J. M. (1996) ADAMs in fertilization and development. Dev. Biol. 180, 389-401 https://doi.org/10.1006/dbio.1996.0313
- Wolfsberg, T. G., Primakoff, P., Myles, D. G., and White, J. M. (1995) ADAM, a novel family of membrane proteins containing a disintegrin and metalloprotease domain, multipotential functions in cell-cell and cell-matrix interactions. J. Cell Biol. 131, 275-278 https://doi.org/10.1083/jcb.131.2.275
- Zhang, W. V. and Stott, N. S. (2004) BMP-2-modulated chondro genic differentiation in vitro involves down-regulation of membrane-bound beta-catenin. Cell Commun. Adhes. 1, 89-102