Allergic skin test

알레르기 피부시험

  • Son, Byong Kwan (Department of Pediatircs, College of Medicine, Inha Univesity) ;
  • Lim, Dae Hyun (Department of Pediatircs, College of Medicine, Inha Univesity)
  • 손병관 (인하대학교 의과대학 소아과학교실) ;
  • 임대현 (인하대학교 의과대학 소아과학교실)
  • Received : 2007.03.12
  • Accepted : 2007.04.08
  • Published : 2007.05.15

Abstract

Allergy skin prick test and intradermal test represent one of the major tools in the diagnosis of IgE-mediated diseases like as atopic asthma, allergic rhinitis, atopic dermatitis, food and drug allergy, and insect bite when properly performed. Skin tests are of particular importance in fields such as allergen standardization, pharmacology, and epidemiology. Even if skin tests seem easy to perform, adequate and proper interpretation requires well-trained physicians who can recognize the numerous factors that may modify the results of skin tests.

Keywords

References

  1. Demoly P, Michel FB, Bousquet J. In vivo method for study of allergy skin test, techniques, and interpretation, In: Allergy Principles and Practices. 5th ed. Missouri: Mosby Co, 1998;430-9
  2. Korean Academy of Pediatric Allergy and Respiratory Disease. Allergic skin test. In: Pediatric Allergy Respiratory. Seoul: Koonja 2005:68-73
  3. Lee JS, Son JW. Allergic skin test. In: Asthma and Allergic Diseases. Seoul: Koonja 2002:135-40
  4. Reshef A, Kagey-Sobotka A, Adkinson N Jr. The pattern and kinetics in human skin of erythema and mediators during the acute and late-phase response (LPR). J Allergy Clin Immunol 1989;84:678-87 https://doi.org/10.1016/0091-6749(89)90296-0
  5. Shalit M, Schwartz LB, von-Allmen C. Release of histamine and tryptase during continuous and interrupted cutaneous challenge with allergen in humans. J Allergy Clin Immunol 1990;86:117-25 https://doi.org/10.1016/S0091-6749(05)80131-9
  6. Foreman JC. Substance P and calcitonin gene-related peptide: effects on mast cells and in human skin. Int Arch Allergy Appl Immunol 1987;82:366-71 https://doi.org/10.1159/000234229
  7. Dolovich J, Hargreave F, Chalmers R. Late cutaneous allergic responses in isolated IgE dependent reactions, J Allergy Clin Immunol 1973;52:38-52 https://doi.org/10.1016/0091-6749(73)90119-X
  8. Charlesworth EN, Kagey-Sobotka A, Schleimer RP. Prednisone inhibits the appearance of inflammatory mediators and the influx of eosinophils and basophils associated with the cutaneous late-phase response to allergen. J Immunol 1991;146:671-6
  9. Pepys J. Skin testing. Br J Hosp Med 1975;14:412-25
  10. Nelson HS, Knoetzer J, Bucher B. Effect of distance between sites and region of the body on results of skin prick tests. J Allergy Clin Immunol 1996;97:596-601 https://doi.org/10.1016/S0091-6749(96)70304-4
  11. Novembre E, Bernardini R, Bertini G. Skin-prick-testinduced anaphylaxis. Allergy 1995;50:511-3 https://doi.org/10.1111/j.1398-9995.1995.tb01187.x
  12. Reid MJ, Lockey RF, Turkeltaub PC. Survey of fatalities from skin testing and immunotherapy 1985-1989. J Allergy Clin Immunol 1993;92:6-15
  13. Mantoux C. Intradermorëaction de la tuberculose. CR Acad Sci 1908;147:355
  14. The waiting period after allergen skin testing and immunotherapy. American Academy of Allergy and Immunology. J Allergy Clin Immunol 1990;85:526-7 https://doi.org/10.1016/0091-6749(90)90166-2
  15. Bernstein IL, Storms WW. Practice parameters for allergy diagnostic testing. Joint Task Force on Practice Parameters for the Diagnosis and Treatment of Asthma. The American Academy of Allergy, Asthma and Immunology and the American College of Allergy, Asthma and Immunology. Ann Allergy Asthma Immunol 1995;75:543-625
  16. Position paper: Allergen standardization and skin tests. The European Academy of Allergology and Clinical Immunology. Allergy 1993;48:48-82 https://doi.org/10.1111/j.1398-9995.1993.tb04698.x
  17. Jang JY, Kim HB, Lee SY, Kim JH, Kim BS, Seo JH, et al. Asthma predictive index in children with recurrent wheezing. Korean J Pediatr 2006;49:298-304 https://doi.org/10.3345/kjp.2006.49.3.298
  18. Skassa-Brociek W, Manderscheid JC, Michel FB. Skin test reactivity to histamine from infancy to old age. J Allergy Clin Immunol 1987;80:711-6. https://doi.org/10.1016/0091-6749(87)90292-2
  19. Vichyanond P, Nelson HS. Circadian variation of skin reactivity and allergy skin tests. J Allergy Clin Immunol 1989;83:1101-6 https://doi.org/10.1016/0091-6749(89)90452-1
  20. Haahtela T, Jokela H. Influence of the pollen season on immediate skin test reactivity to common allergens. Allergy 1980;35:15-21 https://doi.org/10.1111/j.1398-9995.1980.tb01712.x
  21. Long WF, Taylor RJ, Wagner CJ. Skin test suppression by antihistamines and the development of subsensitivity. J Allergy Clin Immunol 1985;76:113-7 https://doi.org/10.1016/0091-6749(85)90813-9
  22. Phillips MJ, Meyrick-Thomas RH, Moodley I. A comparison of the in vivo effects of ketotifen, clemastine, chlorpheniramine and sodium cromoglycate on histamine and allergen induced wheals in human skin. Br J Clin Pharmacol 1983;15:277-86 https://doi.org/10.1111/j.1365-2125.1983.tb01500.x
  23. Spector SL. Effect of beta-adrenergic agents on skin test responses and bronchial challenge responses. Chest 1978;73: 976-7 https://doi.org/10.1378/chest.73.6_Supplement.976
  24. Hagy G, Settipane G. Prognosis of positive allergy skin tests in an asymptomatic population. A three tear followup of college students. J Allergy 1971;48:200-5.
  25. Sampson HA. Comparative study of commercial food antigen extracts for the diagnosis of food hypersensitivity. J Allergy Clin Immunol 1988;82:718-26 https://doi.org/10.1016/0091-6749(88)90070-X
  26. Georgitis JW, Reisman RE. Venom skin tests in insectallergic and insect-nonallegic populations. J Allergy Clin Immunol 1985;76:803-7 https://doi.org/10.1016/0091-6749(85)90752-3
  27. Vervloet D, Arnaud A, Vellieux P. Anaphylactic reactions to muscle relaxants under general anesthesia. J Allergy Clin Immunol 1979;63;348-53 https://doi.org/10.1016/0091-6749(79)90130-1
  28. Grammer LC, Schafer M, Bernstein D. Prevention of chymopapain anaphylaxis by screening chemonucleolysis candidates with cutaneous chymopapain testing. Clin Orthop 1988;234:12-5
  29. Gadde J, Spence M, Wheeler B. Clinical experience with penicillin skin testing in a large inner-city STD clinic. JAMA 1993;270:2456-63 https://doi.org/10.1001/jama.270.20.2456
  30. Moser M, Crameri R, Brust E. Diagnosis value of recombinant Aspergillus fumigatus allergen 1/a for skin testing and serology. J Allergy Clin Immunol 1994;93:1-11 https://doi.org/10.1016/0091-6749(94)90227-5