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스테로이드에 반응 않는 감각신경성 후각소실 환자에서 성상신경절블록의 효과

The Efficacy of Stellate Ganglion Block in Sensorineural Anosmia Patients Unresponsive to Steroid Therapy

  • 문호식 (가톨릭대학교 의과대학 성모병원 마취통증의학교실) ;
  • 이해진 (가톨릭대학교 의과대학 성모병원 마취통증의학교실) ;
  • 성춘호 (가톨릭대학교 의과대학 성모병원 마취통증의학교실) ;
  • 임수진 (가톨릭대학교 의과대학 성모병원 마취통증의학교실) ;
  • 최진환 (가톨릭대학교 의과대학 성모병원 마취통증의학교실)
  • Moon, Ho Sik (Department of Anesthesiology and Pain Medicine, St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Lee, Hae Jin (Department of Anesthesiology and Pain Medicine, St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Sung, Choon Ho (Department of Anesthesiology and Pain Medicine, St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Lim, Su Jin (Department of Anesthesiology and Pain Medicine, St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Choi, Jin Hwan (Department of Anesthesiology and Pain Medicine, St. Mary's Hospital, The Catholic University of Korea College of Medicine)
  • 투고 : 2007.09.28
  • 심사 : 2007.11.09
  • 발행 : 2007.12.10

초록

Background: Anosmia can be frustrating for both the patient and physician, with no clear treatment. We prospectively investigated the effects of stellate ganglion block (SGB) in anosmic patients who were unresponsive to conventional steroid therapy. Methods: Thirteen patients with anosmia were treated with SGB. To evaluate the improvement in olfactory function, we evaluated both changes in subjective symptoms and the butanol threshold test. The number of SGB required for improvement in olfactory function was counted. Results: Seven patients (54%) showed improvement of olfactory function with SGB. The average number of SGB for the first response was $7.4{\pm}5.9times$. Conclusions: These results suggest that SGB may be a good treatment modality for patients with anosmia unresponsive to steroid therapy.

키워드

참고문헌

  1. Temme! AF, Quint C, Schickinger-Fischer B, Klimek L, Stoller E. Hummel T: Characteristics of olfactory disorders in relation to major causes of olfactory loss. Arch Otolaryngol Head Neck Surg 2002; 128: 635-41 https://doi.org/10.1001/archotol.128.6.635
  2. Lee NS, Yoon HR, Park JW, Yum JH, Seo JH, Cho JH, et al: The efficacy of stellate ganglion block in olfactory disorder following upper respiratory tract infection. Korean J Otolaryngol - Head Neck Surg 2003; 46: 568-71
  3. Lee NS, Kim BG, Park JM, Park YS, Kim SW, Lee SK: The effect of superior cervical ganglionectomy on recovery of olfaction in induced anosmic mice. Korean J Otolaryngol - Head Neck Surg 2005; 48: 1462-7
  4. Bramerson A, Johansson L, Ek L, Nordin S, Bende M: Prevalence of olfactory dysfunction: the skovde populationbased study. Laryngoscope 2004; 114: 733-7 https://doi.org/10.1097/00005537-200404000-00026
  5. Holbrook EH, Leopold DA: An updated review of clinical olfaction. Curr Opin Otolaryngol Head Neck Surg 2006; 14: 23-8 https://doi.org/10.1097/01.moo.0000193174.77321.39
  6. Holbrook EH, Leopold DA: Anosmia: diagnosis and management. Curr Opin Otolaryngol Head Neck Surg 2003; 11: 54-60 https://doi.org/10.1097/00020840-200302000-00012
  7. Ofo E, O'Reilly B, O'Doheny A: Olfactory loss. BMJ 2007; 334: 423 https://doi.org/10.1136/bmj.39035.624583.68
  8. Kim JW: Differentiation and regeneration of olfactory neuroepithelial cells. Korean J Otolaryngol - Head Neck Surg 2006; 49: 248-56
  9. Park HJ, Oh JH, Park JH, Ju EJ, Lee HM, Lee SH: Olfactory mucosal findings of patients with persistent anosmia following endoscopic sinus surgery. Korean J Otolaryngo-Head Neck Surg 1999; 42: 455-61
  10. Shin KM: Nerve block in neck . In: Pain medicine. 3rd ed. Edited by The Korean Pain Society: Seoul, Koonja Publishing Inc. 2007, pp 583-8
  11. Kakuyama M, Toda H. Osawa M. Fukuda K: The bilateral effect of stellate ganglion block on the facial skin blood flow. Reg Anesth Pain Med 2000; 25: 389-92 https://doi.org/10.1097/00115550-200007000-00012
  12. Yokoyama M, Nakatsuka H, Itano Y. Hirakawa M: Stellate ganglion block modifies the distribution of lymphocyte subsets and natural-killer cell activity. Anesthesiology 2000; 92: 109-15 https://doi.org/10.1097/00000542-200001000-00021
  13. Landis BN, Konnenh ca, Hummel T: A study on the frequency of olfactory dysfunction, Laryngoscope 2004; 114: 1764-9 https://doi.org/10.1097/00005537-200410000-00017

피인용 문헌

  1. Long-term Results of Stellate Ganglion Block in Patients with Olfactory Dysfunction vol.26, pp.1, 2013, https://doi.org/10.3344/kjp.2013.26.1.57
  2. 비강내 침술을 병행한 후각장애 치험 2례 vol.31, pp.2, 2007, https://doi.org/10.7778/jpkm.2017.31.2.025