Clinical and Experimental Pediatrics

대한소아청소년과학회 (The Korean Pediatric Society)
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건강한 소아에서 발생한 B. cepacia에 의한 폐농양 1례

A case of lung abscess caused by Burkholderia cepacia in healthy child

  • 이정화 (건국대학교 의학전문대학원 소아과학교실) ;
  • 이소희 (건국대학교 의학전문대학원 소아과학교실) ;
  • 홍성진 (건국대학교 의학전문대학원 소아과학교실) ;
  • 최영철 (건국대학교 의학전문대학원 진단방사선과학교실) ;
  • 황은구 (건국대학교 의학전문대학원 흉부외과학교실)
  • Lee, Jung Hwa (Department of Pediatrics, School of Medicine, Konkuk University) ;
  • Lee, So Hee (Department of Pediatrics, School of Medicine, Konkuk University) ;
  • Hong, Seong Jin (Department of Pediatrics, School of Medicine, Konkuk University) ;
  • Choi, Young Chil (Department of Diagnostic Radiology, School of Medicine, Konkuk University) ;
  • Hwang, Eun Gu (Department of Thoracic and Cardiovascular surgery, School of Medicine, Konkuk University)
  • 투고 : 2006.08.23
  • 심사 : 2006.09.28
  • 발행 : 2007.01.15
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초록

B. cepacia는 그람 음성 호기성 세균으로서 주로 면역 기능 저하 환자들에서 기회 감염의 중요한 원인균으로 알려져 있다. 이 세균은 매우 병원성이 강하여 침습적인 괴사성 감염을 일으키며 사망에까지 이르게 할 수 있다. B. cepacia는 여러 항생제에 높은 저항성을 보이므로 한 가지 항생제의 단독 요법보다는 여러 항생제의 병용용법을 사용해야 한다. 저자들은 건강한 소아에서 자연 발생한 B. cepacia에 의한 폐농양을 경험하였고 meropenem과 trimethoprim/sulfamethoxazole 병용 요법과 수술적 치료를 통해 성공적으로 치유한 1례를 보고하고자 한다.

Burkholderia cepacia is a Gram-negative aerobic bacillus known to cause opportunistic infections in the immune-compromised hosts. This microorganism is strongly virulent and causes a necrotising invasive infection that may lead to death. As B. cepacia is highly resistant to various antimicrobials, combination antimicrobial therapy must be used instead of monotherapy. We report a successful treatment of lung abscess that was naturally caused by B. cepacia in a healthy child, through combination antimicrobial therapy of meropenem and trimethoprim/sulfamethoxazole and operative management.

키워드

참고문헌

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