Korean Circulation Journal

The Korean Society of Cardiology (대한심장학회)
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Association of New Parameters Derived from Relation between RR intervals and Left Ventricular Performances with Heart Failure in Patients with Atrial Fibrillation and Normal Systolic Function

좌심실 수축기 기능이 정상인 심방세동 환자에서 RR 간격과 좌심실 활동력 관계에서 유도된 새로운 지수들과 심부전의 연관성

  • Lee, Kwang-Ho (Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University) ;
  • Lee, Kyung-Heon (Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University) ;
  • Choi, Yeo-Won (Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University) ;
  • Choi, Soo-Hee (Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University) ;
  • Lee, Kyung-Eun (Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University) ;
  • Lee, Sung-Ho (Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University) ;
  • Lee, Kwang-Je (Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University) ;
  • Kim, Sang-Wook (Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University) ;
  • Kim, Tae-Ho (Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University) ;
  • Ko, Hong-Sook (Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University) ;
  • Ryu, Wang-Seong (Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University) ;
  • Kim, Chee-Jeong (Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University)
  • 이광호 (중앙대학교 의과대학 순환기내과학교실) ;
  • 이경헌 (중앙대학교 의과대학 순환기내과학교실) ;
  • 최여원 (중앙대학교 의과대학 순환기내과학교실) ;
  • 최수희 (중앙대학교 의과대학 순환기내과학교실) ;
  • 이경은 (중앙대학교 의과대학 순환기내과학교실) ;
  • 이성호 (중앙대학교 의과대학 순환기내과학교실) ;
  • 이광제 (중앙대학교 의과대학 순환기내과학교실) ;
  • 김상욱 (중앙대학교 의과대학 순환기내과학교실) ;
  • 김태호 (중앙대학교 의과대학 순환기내과학교실) ;
  • 고홍숙 (중앙대학교 의과대학 순환기내과학교실) ;
  • 류왕성 (중앙대학교 의과대학 순환기내과학교실) ;
  • 김치정 (중앙대학교 의과대학 순환기내과학교실)
  • Published : 2007.03.30
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Abstract

Background and Objectives：Heart failure (HF) may occur in atrial fibrillation (AF) patients with a normal left ventricular (LV) systolic function if the diastolic function is impaired. The association of new parameters from the relationship between the preceding RR interval (RR-1) and LV outflow peak ejection velocity (Vpe) with systolic function has been reported. The aim of this study was to observe whether these parameters were associated with HF in AF patients with a normal systolic function. Subjects and Methods：AF patients with a normal systolic function were divided into two groups according to the presence (n=16) or absence (n=30) of a history of HF. From the logarithmic equation between RR-1 and Vpe, the slope, Vpe at RR-1 second (Vpe-1), and Slope/Vpe- 1 were calculated. Results：Patients with a history of HF were older (p=0.037) and tended to more frequently have hypertension (p=0.063) than those with no history of HF. The ejection fractions were similar between the two groups. In the coordinates with RR-1 from 0.6 to 1 second, the slope tended to be steeper (p=0.074) and slope/ Vpe-1 was higher in patients with a history of HF (p=0.011). The Vpe-1 was similar between the two groups (p= 0.66). A multiple forward logistic regression analysis showed that slope/Vpe-1 was the only independent variable associated with the occurrence of HF. Slope/Vpe-1 was related with aortic regurgitation, HF history, and the interventricular septal thickness in a multiple stepwise regression analysis. Conclusion：New parameters from the relationship between the RR intervals and LV performances were associated with the occurrence of HF in AF patients with a normal systolic function. This finding suggests that these parameters may be related with the LV diastolic function. (Korean Circulation J 2007;37:119-126)

Keywords

References

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