Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
권호 표지
DOI QR코드

DOI QR Code

A case of neonatal amoebiasis with after-birth vomiting and bloody stool

출생 직후 혈변과 구토 증상이 시작된 Amoebiasis 신생아 1례

  • Kahng, Jimin (Department of Laboratory Medicine, Catholic University College of Medicine) ;
  • Kim, So-Young (Department of Pediatrics, Catholic University College of Medicine)
  • 강지민 (가톨릭대학교 의과대학 임상병리학교실) ;
  • 김소영 (가톨릭대학교 의과대학 소아과학교실)
  • Received : 2007.11.06
  • Accepted : 2007.12.03
  • Published : 2007.12.15
Download PDF
⟨ Previous Next ⟩

Abstract

E. histolytica has a simple life cycle with two stages: an infective cyst and an invasive trophozoite. It lives on humans as its host. Its infection occurs through the ingestion of the cyst form, and the disease begins when the trophozoite, converted at the small intestine, adheres to colonic epithelial cells with a latent period of two days to four months. In some instances, amoebic abscess formations can occur at the liver, lung, brain, or spleen via the lymphoid system. Rare cases of amoebiasis in neonates have been reported, much less any intrauterine infections in the world that may have occurred during the gestation period. We've recently experienced a case of neonatal amoebiasis that entailed after-birth vomiting and bloody stool. The infant seemed pre-infected with E. histolytica before birth.

저자들은 출생 직후부터 심한 혈변과 구토 증상을 보인 신생아의 위액과 변에서 아메바를 확인하여 자궁 내에서 감염된 것으로 판단되는 신생아 아메바증을 경험하고 치료하였기에 문헌 고찰과 함께 보고하는 바이다.

Keywords

References

  1. Berhman RE, Kliegaman RM, Jensom HB. Nelson Textbook of Pediatrics. 17th ed. Philadelphia: WB Saunders Co, 2002: 1123-5
  2. Petri WA Jr, Singh U. Diagnosis and management of amebiasis. Clin Infect Dis 1999;29:1117-25 https://doi.org/10.1086/313493
  3. Haque R, Mondal D, Kirkpatrick BD, Akther S, Farr BM, Sack RB, et al. Epidemiologic and Clinical characteristics of acute diarrhea with emphasis on Entamoeba histolytica infections in preschool children inurban slum of Dhaka, Bangladesh. Am J Trop Med Hyg 2003;69:398-405
  4. Lesh FA. Massive development of amebas in the large intestine. Am J Trop Med Hyg 1975;24:383-92 https://doi.org/10.4269/ajtmh.1975.24.383
  5. Stanley SL Jr. Amoebiasis. Lancet 2003;361:1025-34 https://doi.org/10.1016/S0140-6736(03)12830-9
  6. Seydel KB, Li E, Swanson PE, Stanley SL Jr. Human intestinal epithelial cells produce proinflammatory cytokines in response to infection in a SCID mouse-human intestinal xenograft model of amebiasis. Infect Immun 1997;65:1631-9
  7. Gathiram V, Jackson TF. A longitudinal study of asymptomatic carriers of pathogenic zymodemes of Entamoeba histolytica. S Afr Med J 1987;72:669-72
  8. Haque R, Ali IM, Sack RB, Farr BM, Ramakrishnan G, Petri WA Jr. Amebiasis and mucosal IgA antibody against the Entamoeba histolytica adherence lectin in Bangladeshi children. J Infect Dis 2001;183:1787-93 https://doi.org/10.1086/320740
  9. Abd-Alla MD, Jackson TF, Reddy S, Ravdin JI. Diagnosis of invasive amebiasis by enzyme-linked immunosorbent assay of saliva to detect amebic lectin antigen and anti-lectin immunoglobulin G antibodies. J Clin Microbiol 2000;38:2344-7
  10. Chvez-Rueda K, Agundis-Mata C, Zenteno E, Shibayama M, Tsutsumi V, Leaos-Miranda A, et al. Diagnosis tests using idiotype expression in amebiasis. Arch Med Res 2000; 31:S25-7 https://doi.org/10.1016/S0188-4409(00)00162-4
  11. Delialioglu N, Aslan G, Sozen M, Babur C, Kanik A, Emekdas G. Detection of Entamoeba histolytica/Entamoeba dispar in stool specimens by using enzyme-linked immunosorbent assay. Mem Inst Oswaldo Cruz 2004;99:769-72 https://doi.org/10.1590/S0074-02762004000700019
  12. Stenson WF, Zhang Z, Riehl T, Stanley SL Jr. Amebic infection in the human colon induces cyclooxygenase-2. Infect Immun 2001;69:3382-8 https://doi.org/10.1128/IAI.69.5.3382-3388.2001
  13. Mishra D, Gupta VK, Yadav RB. Role of Entamoeba histolytica in acute watery diarrhea in hospitalized under-five children. Indian Pediatr 2004;41:861-3
  14. Di Rocco F, Sabatino G, Tamburrini G, Ranno O, Valentini P, Caldarelli M. Multiple cerebral amoebic abscesses in a child Neurochir (Wien) Acta Neurochir (Wien) 2004;146: 1271-2 https://doi.org/10.1007/s00701-004-0389-y

Cited by

  1. A Case of Liver Abscess Associated with Umbilical Venous Catheterization in Preterm Infant vol.19, pp.4, 2007, https://doi.org/10.5385/jksn.2012.19.4.280
  2. Recent progress on the discovery of antiamoebic agents vol.26, pp.21, 2007, https://doi.org/10.1016/j.bmcl.2016.09.040