Asian-Australasian Journal of Animal Sciences

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
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Influence of Ligustrum lucidum and Schisandra chinensis Fruits on Antioxidative Metabolism and Immunological Parameters of Layer Chicks

  • Ma, Deying (Institute of Animal Nutrition, Northeast Agricultural University) ;
  • Liu, Yuqin (Institute of Animal Nutrition, Northeast Agricultural University) ;
  • Liu, Shengwang (Division of Avian Infectious Disease, National Key Laboratory of Veterinary Biotechnology Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences) ;
  • Li, Qundao (Institute of Animal Nutrition, Northeast Agricultural University) ;
  • Shan, Anshan (Institute of Animal Nutrition, Northeast Agricultural University)
  • Received : 2006.12.26
  • Accepted : 2007.04.05
  • Published : 2007.09.01
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Abstract

The experiment was conducted to evaluate the effects of Ligustrum lucidum (LL) and Schisandra chinensis (SC) on the growth, antioxidative metabolism and immunity of laying strain male chicks. The results showed that diets supplemented with 1% of either LL or SC had no effects on the growth performance of chicks compared with the control. Furthermore, both LL and SC significantly reduced malondialdehyde (MDA) concentration of serum and heart of chicks (p<0.05). In addition, superoxide dismutase (SOD) activity of serum of the birds was significantly elevated by supplementation with SC (p<0.05). Glutathione reductase (GR) activity of heart and serum of the birds was significantly elevated by supplementation with LL or SC (p<0.05). LL supplementation significantly elevated antibody values against Newcastle Disease virus (NDV)(p<0.05) and lymphoblastogenesis (p<0.05) of the birds. The results suggest that diets supplemented with 1% of either LL or SC may improve immune function and antioxidant status of chicks.

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References

  1. Asikainen, T. M., R. J. Bridges and A. Meister. 1980. Direct evidence for interorgan transport of glutathione and that the non-filtration mechanism for glutathione utilization involve ${\gamma}-glutamyl $ transpeptidase. Biochem. Biophys. Res. Commun. 96:848-853 https://doi.org/10.1016/0006-291X(80)91433-3
  2. Chen, H. L., D. F. Li, B. Y. Chang, L.M. Gong, J. G. Dai and G. F. Yi. 2003. Effects of Chinese herbal polysaccharides on the immunity and growth performance of young broilers. Poult. Sci. 82:364-370 https://doi.org/10.1093/ps/82.3.364
  3. Chiu, P. Y., D. H. Mak, M. K. Poon and K. M. Ko. 2002. In vivo antioxidant action of lignan-enriched extract of schisandra fruit and an anthraquinone-containing extract of polygonum root in comparison with sahisandrin B and emodin. Planta Med. 68:951-956 https://doi.org/10.1055/s-2002-35661
  4. Din, X. F. 1995. Preliminary study of Schisandrin B pharmacodynamics. Journal of Bai Qiu En Medical University. 21:147-149 (in Chinese)
  5. Gao, J. P., Y. Q. Yu and D. F. Chen. 2003. Determination of lignans of Schisandra rubriflora by HPLC. Chinese Traditional and Herbal Drugs. 34:950-951 (in Chinese)
  6. Halliwell, B. 1995. The importance of free radicals and catclytic metal ions in human diseases. Mol. Aspects. 8:89
  7. He, Z. D., P. P. H. But, T. W. Chan, H. Dong, H. X. Xu, C. P. Lau and H. D. Sun. 2001. Antioxidative glucosides from the fruits of Ligustrum lucidum. Chem. Pharm. Bull (Tokyo) 49:780-784 https://doi.org/10.1248/cpb.49.780
  8. Hevener, W., P. A. Routh and G. W. Almond. 1999. Effects of immune challenge on concentrations of serum insulin-like growth factor-I and growth performance in pigs. Can. Vet. J. 40:782-786
  9. Iovine, N. M. and M. J. Blaser. 2004. Antibiotics in animal feed and spread of resistant Camylobacter from poultry to humans. Emerg. Infect. Dis. 10:1158-1159 https://doi.org/10.3201/eid1006.040403
  10. Ip, S. P., D. H. Mak and P. C. Li. 1996. Effect of a ligan-enriched extract of Schisandra chinensis on aflatoxin B1 and cadmium chloride-indued hepatotosicity in rats. Pharmacol. Toxicol. 78:413-416 https://doi.org/10.1111/j.1600-0773.1996.tb00228.x
  11. Jin, R. L., L. Wan and T. Mitsuishi. 1995. Effect of shi-ka-ron and Chinese herbs in mice treated with anti-tumor agent mitomycin C. Zhongguo zhong Xi Yi Jie He Za Zhi. 15:101-103 (in Chinese)
  12. Kalorey, D. R., N. V. Kurkure, J. S. Ramgaonkar, P. S. Sakhare, Shubhangi Warke and N. K. Nigot. 2005. Effect of Polyherbal Feed Supplement Growell' during Induced Aflatoxicosis, Ochratoxicosis and Combined Mycotoxicoses in Broiler. Asian-Aust. J. Anim. Sci. 18:375-378 https://doi.org/10.5713/ajas.2005.375
  13. Kehrer, J. P. 1993. Free radicals as mediators of tissue injury and disease. Crit. Rev. Toxicol. 23:21-48 https://doi.org/10.3109/10408449309104073
  14. Kim, I. H., J. W. Hong, O. S. Kwon, B. J. Min, W. B. Lee and K. S. Shon. 2004. Influences of Plant Extract Supplementation on Performance and Blood Characteristics in Weaned Pigs. Asian-Aust. J. Anim. Sci. 17:374-378 https://doi.org/10.5713/ajas.2004.374
  15. Klasing, K. C. 1998. Nutritional modulation of resistance to infectious diseases. Poult. Sci. 77:1119-1125 https://doi.org/10.1086/315904
  16. Li, H. and Q. Wang. 2004. Evaluation of free hydroxyl radical scavenging activities of some Chinese herbs by capillary zone electrophoresis with amperometric detection. Anal. Bioanal. Chem. 378:1801-1805 https://doi.org/10.1007/s00216-004-2509-1
  17. Liu, S. W. 1998. Effect of vaccination Newcastle disease virus on chicken lymphocytes. Chinese Journal of Animal and Poultry infectious diseases. 20:140-145 (in Chinese)
  18. Liu, X. Y. 1999. Stress and immunity. In: Poultry Immunology. (Ed. T. B. Yin). China Agriculture Press, Beijing, China. pp. 230-252
  19. Luo, H. S. and D. H. Luo. 1999. ligustrum lucidum and schisandra chinensis. In: Immunology of Chinese medicine (Ed. H. S. Luo and D. H. Luo). Beijing Medical University Publisher, Beijing, P. R. China, pp. 103-114 (in Chinese)
  20. Ma, D. Y., A. S. Shan, Q. D. Li and J. Du. 2003. Effects of Chinese medical herbs on growth and immunization of laying chicks. J. North. Agric. Univ. 10:121-125
  21. Ma, D. Y., A. S. Shan, Z. H. Chen, J. Du, K. Song, J. P. Li and Q. Y. Xu. 2005. Effects of ligustrum lucidum and schisandra chinensis on the egg production, antioxidant status and immunity of laying hens during heat stress. Arch. Anim. Nutr. 59:439-447 https://doi.org/10.1080/17450390500353499
  22. Ma, D. Y., Q. D. Li, J. Du, Y. Q. Liu, S. W. Liu and A. S. Shan. 2006. Influence of Mannan Oligosaccharide, Ligustrum lucidum and Schisandra chinensis on parameters of antioxidative and immunological status of broilers. Arch. Anim. Nutr. 60:467-476 https://doi.org/10.1080/17450390600979375
  23. Maslak, D. M. and D. L. Reynolds. 1995. Mitogenic responses of the head-associated lymphoid tissues of the chicken. Avian Dis. 39:1-8 https://doi.org/10.2307/1591975
  24. National Research Council. 1994: Nutrient Requirement of Poultry. 9th ed. National Academe press, Washington, DC
  25. Ohsugi, M. W. Fan, K. Hase, Q. Xiong, Y. Tezuka, K. Komatsu, T. Namba, T. Saitoh, K. Tazawa and S. Kadota. 1999. Activeoxygen scavenging activity of traditional nourishing-tonic herbal medicines and active constituents of Rhodiola sacra. J Ethnopharmacol. (Japan). 67:111-119 https://doi.org/10.1016/S0378-8741(98)00245-1
  26. Salisbury, J. G., T. J. Nicholls, A. M. Lammerding, J. Turnidge and M. J. Nunn. 2002. A risk of analysis framework for the longterm management antibiotic resistance in food-producing animals. Int. J. Animicrob. Agents. 20:153-164 https://doi.org/10.1016/S0924-8579(02)00169-3
  27. SAS. 1996. Institute. SAS User's Guide: Statistics, SAS Institute Inc., Cary, NC
  28. Shi, L., Z. Cai, G. Wu, S. Yang and Y. Ma. 1998. RP-HPLC determination of water-soluble active constituents and oleanolic acid in the fruits of Ligustrum lucidum Ait. collected from various areas. Zhongguo Zhong Yao Za Zhi 23:77-79, 127(In Chinese)
  29. Sun, Y. E., M. Hersh and S. L. Lee. 1983. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J. Biol. Response Mod. 2:227-237 (in Chinese)
  30. Takahashi, K., T. Mashiko and Y. Akiba. 2000. Effect of dietary concentration of xylitol on growth in male broiler chicks during immunological stress. Poult. Sci. 79:743-747 https://doi.org/10.1093/ps/79.5.743
  31. Tian, G. Y. and Y. C. Feng. 1994. Progress in the research and application of polysaccharides. Chem. Prog. 6:44-48 (in Chinese)
  32. Yim, T. K., W. K. Wu and W. F. Pak. 2001. Hepatoprotective action of an oleanolic acid-enriched extract of Ligustrum lucidum fruit if mediated through an enhancement on hepatic glutathione regeneration capacity in mice. Phytother Res. 15:589-592 https://doi.org/10.1002/ptr.878
  33. Zang, K. T. 2000. Immunity of Chinese medicine. In: Clinical Chinese medicine pharmacology. (Ed. K. T. Zang). Beijing, P. R. China: Military Medical Science publisher. pp. 301-326 (in Chinese)
  34. Zhang, L. J., W. H. Zhang and S. H. Zhao. 2002. Study on the extraction and purification of polysaccharide from schisandrachinensis. J. Anshan Normal Univ. 4:58-60(in Chinese)
  35. Zhu, M. K., K. F. Lin and R. Y. Yeung. 1999. Evaluation of the protective effects of Schisandra chinensis on Phase I drug metabolism using a $CCl_4$ intoxication model. J. Ethnopharmacol. 67:61-68 https://doi.org/10.1016/S0378-8741(98)00210-4
  36. Zhu, M. K., K. F. Lin and R. Y. Yeung. 2000. Improvement of phase I drug metabolism with Schisandra chinensis against $CCl_4$ hepatotoxicity in a rat model. Planta Med. 66:521-525 https://doi.org/10.1055/s-2000-11202

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