The Korean Journal of Cytopathology (대한세포병리학회지)

The Korean Society for Cytopathology (대한세포병리학회)
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Fine Needle Aspiration Cytology of Extranodal Marginal Zone B cell Lymphoma with Abundant Plasma Cells and Eosinophilic Histiocytes in Parotid Gland

귀밑샘의 형질세포와 호산성 조직구를 다량 함유한 림프절외 변연부 B-세포 림프종의 세침흡인 세포검사 소견 -1예 보고-

  • Lee, Young-Seok (Department of Pathology, Korea University Anam Hospital) ;
  • An, Jung-Suk (Department of Pathology, Korea University Anam Hospital) ;
  • Chae, Yang-Seok (Department of Pathology, Korea University Anam Hospital) ;
  • Yeom, Bom-Woo (Department of Pathology, Korea University Anam Hospital) ;
  • Choi, Jong-Sang (Department of Pathology, Korea University Anam Hospital) ;
  • Kim, Chul-Hwan (Department of Pathology, Korea University Anam Hospital)
  • 이영석 (고려대학교 안암병원 병리과) ;
  • 안정석 (고려대학교 안암병원 병리과) ;
  • 채양석 (고려대학교 안암병원 병리과) ;
  • 염범우 (고려대학교 안암병원 병리과) ;
  • 최종상 (고려대학교 안암병원 병리과) ;
  • 김철환 (고려대학교 안암병원 병리과)
  • Published : 2007.09.30
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Abstract

The authors present the fine needle aspiration cytology (FNAC) cytologic findings of a case of extranodal marginal zone B cell lymphoma (MZBCL), which featured abundant plasma cells and eosinophilic histiocytes arising in both parotid glands. A 49-year-old female presented with palpable masses in both parotid glands. She had been suffering from systemic lupus erythematosus and rheumatoid arthritis. The lesions were evaluated by FNAC and smears showed a small number of clusters of oncocytic cells with abundant eosinophilic granular cytoplasm and small nuclei, intermixed with small to medium-sized lymphoid cells containing round to lobulated nuclei, which suggested Warthin's tumor. Some of lymphoid cells had a plasmacytoid appearance, and some scattered large cells contained a large amount of eosinophilic cytoplasm. Bilateral superficial parotidectomy was performed and a histopathologic study indicated MZBCL with abundant plasma cells, intermixed with eosinophilic histiocytes. The presence of oncocytic cells and a mixture of lymphoid and plasma cells indicates Warthin's tumor, but the cytologic features of a relatively monotonous small to medium-sized lymphoid infiltrate suggest the possibility of MZBCL in the clinical setting of an FNAC study performed on a patient suffering from a connective tissue disease.

Keywords

References

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