Journal of Korean Neurosurgical Society

  • 제42권1호
  • /
  • Pages.46-48
  • /
  • 2007
  • /
  • 2005-3711(pISSN)
  • /
  • 1598-7876(eISSN)
대한신경외과학회 (The Korean Neurosurgical Society)
권호 표지

Vertebral Metastasis from Squamous Cell Carcinoma of the Anal Canal

  • Jwa, Cheol-Su (Department of Neurosurgery National Medical Center) ;
  • Sim, Sook-Young (Department of Neurosurgery National Medical Center) ;
  • Kim, Gang-Hyun (Department of Neurosurgery National Medical Center) ;
  • Kang, Jae-Kyu (Department of Neurosurgery National Medical Center)
  • 발행 : 2007.07.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Distant metastasis of squamous cell carcinoma from the anal canal is an uncommon event. However, hematogenous spread to the vertebrae may occur in the course of this disease. The route of metastasis from the anal canal seems to be Batson's vertebral venous system. A 52-year-old female patient presented with lower back and right leg pain of one-week history. She has undergone radiotherapy and chemotherapy for squamous cell carcinoma of the anal canal and then was followed by surgical resection. Three months later, magnetic resonance images of the lumbar spine disclosed a well-enhanced mass of L5 vertebral body compressing the thecal sac. Surgical decompression and biopsy were performed. Histopathological study confirmed carcinoma of the squamous cell origin. We report a ra re case of vertebral metastasis from squamous cell carcinoma of the anal canal with a pertinent review of literature.

키워드

참고문헌

  1. Batson OV : The function of the vertebral veins and their role in the spread of metastases. 1940. Clin Orthop Relat Res 312 : 4-9, 1995
  2. Boman BM, Moertel CG, O'Connell MJ, Scott M, Weiland LH, Beart RW, et al : Carcinoma of the anal canal. A clinical and pathologic study of 188 cases. Cancer 54 : 114-125, 1984 https://doi.org/10.1002/1097-0142(19840701)54:1<114::AID-CNCR2820540124>3.0.CO;2-P
  3. Cho DY, Wang YC, Chen JT : Intradural metastasis to the cauda equina from carcinoma of the anus. Spine 20 : 2341-2344, 1995 https://doi.org/10.1097/00007632-199511000-00014
  4. Fukuoka K, Narita N, Saijo N : Increased expression of sialyl Lewis (x) antigen is associated with distant metastasis in lung cancer patients : immunohistochemical study on bronchofiberscopic biopsy specimens. Lung Cancer 20 : 109-116, 1998 https://doi.org/10.1016/S0169-5002(98)00016-6
  5. Greenall MJ, Magill GB, Quan SH, DeCosse JJ : Recurrent epidermoid cancer of the anus. Cancer 57 : 1437-1441, 1986 https://doi.org/10.1002/1097-0142(19860401)57:7<1437::AID-CNCR2820570733>3.0.CO;2-T
  6. Kuehn PG, Beckett R, Eisenberg H, Reed JF : Hematogenous metastasis from epidermoid carcinoma of the anal canal. Am J Surg 109 : 445-449, 1965 https://doi.org/10.1016/S0002-9610(65)80172-6
  7. Lal P, Halder S, Datta NR : Carcinoma of the penis metastasizing to the dorsal spine. A case report. Urol Int 62 : 249-251, 1999 https://doi.org/10.1159/000030407
  8. Nakamori S, Kameyama M, Imaoka S, Furukawa H, Ishikawa O, Sasaki Y, et al : Involvement of carbohydrate antigen sialyl Lewis (x) in colorectal cancer metastasis. Dis Colon Rectum 40 : 420-431, 1997 https://doi.org/10.1007/BF02258386
  9. Niimi K, Yoshizawa M, Nakajima T, Saku T : Vascular invasion in squamous cell carcinomas of human oral mucosa. Oral Oncol 37 : 357-364, 2001 https://doi.org/10.1016/S1368-8375(00)00097-X
  10. Ono Y, Nakajima T, Saku T : Vascular invasion of O-1N, hamster squamous cell carcinoma with high potential of lymph node metastasis : ultrastructural comparison between lymphatics and blood vessels. Pathol Int 48 : 254-264, 1998 https://doi.org/10.1111/j.1440-1827.1998.tb03903.x
  11. Patchell RA, Tibbs PA, Regine WF, Payne R, Saris S, Kryscio RJ, et al : Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer : a randomised trial. Lancet 366 : 643-648, 2005 https://doi.org/10.1016/S0140-6736(05)66954-1
  12. Richards JC, Beahrs OH, Woolner LB : Squamous cell carcinoma of the anus, anal canal, and rectum in 109 patients. Surg Gynecol Obstet 114 : 474-482, 1962