Bone Cement Augmentation of Pedicular Screwing in Severe Osteoporotic Spondylolisthetic Patients

  • Kim, Hyeun-Sung (Departments of Neurosurgery Mokpo Hankook Hospital) ;
  • Park, In-Ho (Departments of Neurosurgery Mokpo Hankook Hospital) ;
  • Ryu, Jae-Kwang (Departments of Neurosurgery Mokpo Hankook Hospital) ;
  • Kim, Seok-Won (Departments of Neurosurgery College of Medicine, Chosun University) ;
  • Shin, Ho (Departments of Neurosurgery College of Medicine, Chosun University)
  • Published : 2007.07.30

Abstract

Objective : The purpose of this study was to determine the effect of bone cement augmentation of pedicular screwing in severe osteoporotic spondylolisthetic patients. Methods : Twenty patients with spondylolisthesis (8 : spondylolytic spondylolisthesis 12 : degenerative spondylolisthesis) who had undergone pedicular screwing and interbody fusion for osteoporotic lumbar spine (T-score on bone mineral density<-3.0) from 2002 to 2005 were reviewed. Mean age was 62.3 years with 3 male and 17 female patients. Average follow-up period was 14 months. Average T-score on bone mineral density (BMD) was -3.62. After decompression of neural elements, about 6cc of polymethylmethacrylate (PMMA) was injected into the each vertebral body through transpedicular route. All patients underwent one level interbody fusion and pedicular screw fixation. Clinical outcome was assessed using Oswestry Disability Index (ODI) on the last clinical follow-up. In addition, a modified MacNab's grading criteria was used to objectively assess patient's outcome postoperatively. Radiographic analysis of sagittal contour was assessed preoperatively, immediately postoperatively, and at final follow-up including fusion rate. Results : Eighteen of 20 patients were graded as excellent or good according to the modified MacNab's criteria. An significant improvement of ODI was achieved in both groups. Mean sagittal angle at the preoperative state, postoperative state and at the last follow-up state was $11.0^{\circ},\;20.1^{\circ}$ and $18.3^{\circ}$, respectively, with mean sagittal angle correction gain $7.3^{\circ}$. Firm fusion was achieved in all patients. There were one compression fracture above the fused segment after 6 months follow-up and one case of seroma. But there were no postoperative complications related to bone cement leakage and pedicular screwings such as screw pullout or screw cut-up. Conclusion : Bone cement augmentation of pedicular screwing can be an effective procedure for osteoporotic lumbar spine in spondylolisthetic patients.

Keywords

References

  1. Brantley AG, Mayfield JK, Koeneman JB, Clark KR : The effects of pedicle screw fit. An in vitro study. Spine 19 : 1752-1758, 1994 https://doi.org/10.1097/00007632-199408000-00016
  2. Cho KN, Yoon HK, Jeon HS, Jeon SJ, Cho HJ, Hong JW, et al : Effect of bone cement augmentation of pedicular screwing for osteoporotic lumbar spine. Journal of Korean Spine Surg 9 : 223-229, 2002 https://doi.org/10.4184/jkss.2002.9.3.223
  3. Gill GG, Manning JG, White HL : Surgical treatment of spondylolisthesis without spine fusion; excision of the loose lamina with decompression of the nerve roots. J Bone Joint Surg Am 37 : 493- 520, 1955 https://doi.org/10.2106/00004623-195537030-00005
  4. Halvorson TL, Kelley LA, Thomas KA, Whitecloud TS 3rd, Cook SD : Effects of bone mineral density on pedicle screw fixation. Spine 19 : 2415-2420, 1994 https://doi.org/10.1097/00007632-199411000-00008
  5. Hasegawa K, Takahashi HE, Uchiyama S, Hirano T, Hara T, Washio T, et al : An experimental study of a combination method using a pedicle screw and laminar hook for the osteoporotic spine. Spine 22 : 958-962, 1997 https://doi.org/10.1097/00007632-199705010-00004
  6. Hu SS : Internal fixation in the osteoporotic spine. Spine (Suppl 24) 22 : 43S-48S, 1997 https://doi.org/10.1097/00007632-199712151-00008
  7. Humphreys SC, Hodges SD, Patwardhan AG, Eck JC, Murphy RB, Covington LA : Comparison of posterior and transforaminal approaches to lumbar interbody fusion. Spine 26 : 567-571, 2001 https://doi.org/10.1097/00007632-200103010-00023
  8. Kim YS, Yoon DH, Park HC, Cho YE, RohSW : Posterior lumbar interbody fusion with threaded fusion cage (TFC). J Korean Neurosurg Soc 22 : 493-503, 1993
  9. Niskanen RO : The Oswestry Low Back Pain Disability Questionnaire. a two-year follow-up of spine surgery patients. Scand J Surg 91 : 208- 211, 2002
  10. Okuyama K, Sato K, Abe E, Inaba H, Shimada Y, Murai H : Stability of transpedicle screwing for the osteoporotic spine. Spine 18 : 2240- 2245, 1993 https://doi.org/10.1097/00007632-199311000-00016
  11. Sherman FC, Rosenthal RK, Hall JE : Spine fusion for spondylolysis and spondylolisthesis in children. Spine 4 : 59-66, 1979 https://doi.org/10.1097/00007632-197901000-00010
  12. Soshi S, Shiba R, Kondo H, Murota K : An experimental study on transpedicular screw fixation in relation to osteoporosis of the lumbar spine. Spine 16 : 1335-1341, 1991 https://doi.org/10.1097/00007632-199111000-00015
  13. Steiner ME, Micheli LJ : Treatment of symptomatic spondylolysis and spondylolisthesis with the modified Boston brace. Spine 10 : 937- 943, 1985 https://doi.org/10.1097/00007632-198512000-00013
  14. Tan JS, Bailey CS, Dvorak MF, Fisher CG, Cripton PA, Oxland TR : Cement augmentation of vertebral screws enhances the interface strength between interbody device and vertebral body. Spine 32 : 334-341, 2007 https://doi.org/10.1097/01.brs.0000253645.24141.21
  15. Zdeblick TA, Kunz DN, Cooke ME, McCabe R : Pedicle screw pullout strength. Correlation with insertional torque. Spine 18 : 1673-1676, 1993 https://doi.org/10.1097/00007632-199309000-00016
  16. Zindrick MR, Wiltse LL, Widell EH, Thomas JC, HollandWR, Field BT, et al : A biomechanical study of intrapeduncular screw fixation in the lumbosacral spine. Clin Orthop Relat Res 203 : 99- 112, 1986