Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
권호 표지

MULTIPLE MYELOMA IN THE MANDIBLE MANIFESTED AS ORAL LESION OF PLASMACYTOMA: A CASE REPORT

악골에서 발견된 multiple myeloma의 구강내 plasmacytoma 병소: 증례보고

  • Lee, Jeong-A (Department of Oral and Maxillofacial Surgery, Kang-nam St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Park, Ji-Young (Department of Oral and Maxillofacial Surgery, Kang-nam St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Yun, Sung-Hun (Department of Oral and Maxillofacial Surgery, Kang-nam St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Park, Min-Kyu (Department of Oral and Maxillofacial Surgery, Kang-nam St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Kim, Chang-Hyun (Department of Oral and Maxillofacial Surgery, Kang-nam St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Park, Je-Uk (Department of Oral and Maxillofacial Surgery, Kang-nam St. Mary's Hospital, College of Medicine, The Catholic University of Korea)
  • 이정아 (가톨릭대학교 강남성모병원 구강악안면외과) ;
  • 박지영 (가톨릭대학교 강남성모병원 구강악안면외과) ;
  • 윤성훈 (가톨릭대학교 강남성모병원 구강악안면외과) ;
  • 박민규 (가톨릭대학교 강남성모병원 구강악안면외과) ;
  • 김창현 (가톨릭대학교 강남성모병원 구강악안면외과) ;
  • 박재억 (가톨릭대학교 강남성모병원 구강악안면외과)
  • Published : 2007.01.31
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Abstract

Plasma cell neoplasms are generally categorized into four groups; multiple myeloma(MM), solitary plasmacytoma of the bone(SPB), plasma cell leukemias, and extramedullary plasmacytomas(EMP). These tumors may be further described as localized or diffuse in presentation. Localized plasma cell neoplasms are rare occurrences and include solitary plasmacytomas of the skeletal system, which account for 2-5% of all plasma cell neoplasms and extramedullary plasmacytomas of the soft tissue, which account for approximately 3% of all such neoplasms. A plasmacytoma is defined as any discrete, most likely solitary mass of neoplastic plasma cells either in the bone marrow or in various soft tissue sites. Diffuse lesions include the other two groups, multiple myeloma and plasma cell leukemia. The relationship between these processes has not yet been definitively characterized, but there appears to be a continuum in which both SPB and EMP often progress to MM. The patient was referred who had continuous deep throbbing bone pain and swelling on the left posterior gingival area of the mandible after extraction of the first and second molar. The result of intraoperative excisional biopsy of the lesion was confirmed as a plasmacytoma. And it revealed systemic multiple myeloma through the further diagnostic work-up. It is worth to report because of a rare case of multiple myeloma found in oral cavity as a form of plasmacytoma.

Keywords

References

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