대한두경부종양학회지 (Korean Journal of Head & Neck Oncology)

  • 제23권2호
  • /
  • Pages.138-141
  • /
  • 2007
  • /
  • 1229-5183(pISSN)
  • /
  • 2586-2553(eISSN)
대한두경부종양학회 (The Korean Society for Head and Neck Oncology)
권호 표지

고분화성 갑상선 암종의 재발과 관련된 위험인자 분석

Analysis of Risk Factors Related to the Recurrence of well Differentiated Thyroid Carcinoma

  • 이상준 (단국대학교 의과대학 이비인후-두경부외과학교실) ;
  • 정필상 (단국대학교 의과대학 이비인후-두경부외과학교실) ;
  • 김영생 (단국대학교 의과대학 이비인후-두경부외과학교실) ;
  • 윤경섭 (단국대학교 의과대학 이비인후-두경부외과학교실)
  • Lee, Sang-Joon (Department of Otolaryngology-Head and Neck Surgery, Dankook University College of Medicine) ;
  • Chung, Phil-Sang (Department of Otolaryngology-Head and Neck Surgery, Dankook University College of Medicine) ;
  • Kim, Young-Saeng (Department of Otolaryngology-Head and Neck Surgery, Dankook University College of Medicine) ;
  • Yun, Kyung-Sub (Department of Otolaryngology-Head and Neck Surgery, Dankook University College of Medicine)
  • 발행 : 2007.11.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Objectives : Well differentiated thyroid carcinoma(WDTC) has relatively good prognosis. But recurrence is associated with increased morbidity and mortality, and always results in reoperation. So it is important to evaluate the risk factors relative to the recurrence. The aim of this study is to evaluate the risk factors of recurrence. Materials and Method : Two hundred seventeen patients who had undergone thyroidectomy and proved as WDTC from January 1999 to December 2004 was included in the study. We reviewed patient-related and tumorrelated factors respectively and analyzed the correlation with tumor recurrence. Results : Fourteen patients from two hundreds seventeen had recurred. Recurrence rate was 6.5%, and average interval of recurrence was 28 month. Male, age over 45, multiple mass, and advanced TMN stage patient group show higher recurrence rate, but no statistical significance. However, the recurrence rate of lymph node metastasis, tumor size>1.5cm, and extracapsular invasion group were statistically high. Conclusion : Lymph node metastasis, tumor size and extracapsular invasion are significant risk factors related to the recurrence of WDTC.

키워드

참고문헌

  1. Cushing SL, Palme CE, Audet N, Eski S, Walfish G, Freeman JL: Prognositic factors in well differentiated thyroid carcinoma. Laryngoscope. 2004;114:2110-2115 https://doi.org/10.1097/01.mlg.0000149442.22393.e2
  2. Annual report of the Korea central cancer, Jan, 2002-Dec, 2002. Korea central cancer registry, Ministry of health and welfare. Republic of Korea, February, 2003
  3. Park JS, Choi JS, Park BU: Treatment of papillary thyroid carcinoma. Korean J Head and Neck Oncology. 1993;9:175-182
  4. Grant CS, Hay ID, Gough IR, Bergstralh EJ, Goellner JR, Mc-Conahey WM: Local recurrence in papillary thyroid carcinoma: Is extent of surgical resection important? Surgery. 1988 Dec;104:954-962
  5. Segal K, Shpitzer T, Hazan A, Bachar G, Marshak G, Popovtzer A: Invasive well differentiated thyroid carcinoma: effect of treatment modalities on outcome. Otolaryngol Head and Neck Surg. 2006;134:819-822 https://doi.org/10.1016/j.otohns.2005.11.040
  6. Udelsman R, Shara AR: Is total thyroidectomy the best possible surgical management for well-differentiated thyroid cancer? Lancet Oncol. 2005;6:529-531 https://doi.org/10.1016/S1470-2045(05)70247-3
  7. Hay ID, McConahey WM, Goellner JR: Managing patients with papillary thyroid carcinoma: insights gained from the Mayo Clinic's experience of treating 2512 consecutive patients during 1940 through 2000. Trans Am Clin Clim Assoc. 2002;113:241-260
  8. Udelsman R, Lakatos E, Ladenson P: Optimal surgery for papillary thyroid carcinoma. World J Surg. 1996;20:88-93 https://doi.org/10.1007/s002689900016
  9. Shah JP, Loree TR, Dharker D, Strong EW: Lobectomy versus total thyroidectomy for differentiated carcinoma of the thyroid: a matched pair analysis. Am J Surg. 1993;166:331-335 https://doi.org/10.1016/S0002-9610(05)80326-5
  10. Shaha AR, Shah JP, Loree TR: Low-risk differentiated thyroid cancer: the need for selective treatment. Ann Surg Oncol. 1997;4:328-333 https://doi.org/10.1007/BF02303583
  11. Cady B: Presidential address. Beyond the risk groups-a new look at differentiated thyroid cancer. Surgery. 1998;124:947-957 https://doi.org/10.1016/S0039-6060(98)70034-0