Mycobiology

The Korean Society of Mycology (한국균학회)
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Chemical Components of Paecilomyces tenuipes (Peck) Samson

  • Hong, In-Pyo (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, R.D.A.) ;
  • Nam, Sung-Hee (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, R.D.A.) ;
  • Sung, Gyoo-Byung (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, R.D.A.) ;
  • Chung, In-Mo (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, R.D.A.) ;
  • Hur, Hyeon (Department of Applied Biology, Dongguk University) ;
  • Lee, Min-Woong (Department of Applied Biology, Dongguk University) ;
  • Kim, Mi-Kyung (Biofood Network Center, Ewha Woman's University) ;
  • Guo, Shun-Xing (Institute of Medicinal Plant, Chinese Academy of Medical Sciences)
  • Published : 2007.12.31
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Abstract

The caterpillar-shaped Chinese medicinal mushroom (DongChongXiaCao) looks like a worm in the winter and like a grass in the summer. The fruiting body has been regarded as popular folk or effective medicines used to treat human diseases such as asthma, bronchial and lung inflammation, and kidney disease. The fruiting bodies of Paecilomyces tenuipes that formed on the living silkworm (Bombyx mon) host were used in this examination. This study was carried out to investigate the proximate composition, soluble sugar, amino acid and fatty acid profiles, and contents of the bioactive ingredient including adenosine and D-mannitol in the fruiting-bodies. The moisture content was 57.56%. Soluble sugars found were glycerol, glucose, mannitol and sucrose, and the contents exceeded $24\;mgg^{-1}dry$ weight. Total free amino acid content was $17.09\;mgg^{-1}dry$ weight. Arginine, glycine, proline and tyrosine were main amino acids. The content of oleic acid in fatty acids was high. Adenosine was more abundant in fruiting bodies than corpus.

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References

  1. AOAC. 1995. Official methods of analysis (16th ed). Washington, DC. Association of Official Analytical Chemists
  2. Bok, J. W., Lermer, L., Chilton, J., Klingeman, H. G and Towers, G H. 1999. Antitumor sterols from the mycelia of Cordyceps sinensis. Phytochemistry 51(7): 891-898 https://doi.org/10.1016/S0031-9422(99)00128-4
  3. Chang, H. L., Chao, G. R., Chen, C. C. and Mau, J. L. 2001. Non-volatile taste components of Agaricus blazei, Antrodia camphorata and Cordyceps militaris mtcelia. Food Chemistry 74: 203-207 https://doi.org/10.1016/S0308-8146(01)00127-3
  4. Chen, H. K. 1986. Studies on the characteristics of taste-active components in mushroom concentrate and its powderization. Master's Thesis, National Chung-Hsing University, Taichung, Taiwan
  5. Chiou, W. F., Chang, P. C., Chou, C. J. and Chen, C. F. 2000. Protein constituent contributes to the hypotensive and vasorelaxant activities of Cordyceps sinensis. Life Sci. 66(14): 1369-1376 https://doi.org/10.1016/S0024-3205(00)00445-8
  6. Cho, S. Y., Shin, K. H., Song, S. K. and Sung, J. M. 1999. Mass production and useful material development of the entomopathogenic fungi growing on the silkworm, Rural Development Administration Report, 1-234
  7. Crisan, E. V. and Sands, A. 1978. Nutritional value. In S. T. Chang and W. A. Hayes, The biology and cultivation of edible mushrooms (pp. 137-165). New York: Academic Press
  8. Furuya, T., Hirotani, M. and Matsuzawa, M. 1983. $N^6$-(2-hydroxyethyl) adenosine, a biologically active compound from cultured mycelia of Cordyceps and Isaria species. Phytochemistry 22: 2509-2512 https://doi.org/10.1016/0031-9422(83)80150-2
  9. Huang, B. M., Hsu, C. C, Tsai, S. J., Sheu, C. C. and Leu, S. F. 2001. Effect of Cordyceps sinensis on testosterone production in normal mouse Leydig cells. Life Sci. 69: 2593-2602 https://doi.org/10.1016/S0024-3205(01)01339-X
  10. Huang, B. M., Stocco, D. M. and Norman, R. L. 1997 The cellular mechanism of corticotropin-releasing hormone (CRH) stimulated steroidogenesis in mouse Leydig cells are similar to those for LH. J. Androl. 18(5): 528-534
  11. Kim, K. M., Kwon, Y. G., Chung, H. T., Yun, Y. G., Pae, H. O., Han, J. A., Ha, K. S., Kim, T. W. and Kim, Y. M. 2003. Methanol extract of Cordyceps pruinosa inhibits in vitro and in nivo inflammatory mediators by suppressing NF-$\kappa$B activation. Toxicology and Applied Pharmacology 190: 1-8 https://doi.org/10.1016/S0041-008X(03)00152-2
  12. Kobayashi, Y. 1982. Key to the taxa of the genera Cordyceps and Torrubiella. Trans. Mycol. Soc. Jpn. 23(3): 29-364
  13. Kuo, Y. C., Lin, C. Y., Tsai, W. J., Wu, C. L., Chen, C. F. and Shiao, M. S. 1994. Growth inhibitors against tumor cells in Cordyceps sinensis other than cordycepin and polysaccharides. Cancer Investi. 12(6): 611-615 https://doi.org/10.3109/07357909409023046
  14. Kuo, Y. C., Tsai, W. J., Shiao, M. S., Chen, C. F. and Lin, C. Y. 1996. Cordyceps sinensis as an immunomodulatory agent. Am. J. Chin. Med. 24(2): 111-125 https://doi.org/10.1142/S0192415X96000165
  15. Li, Q. S., Zeng, W., Yi, D. H. and Huang, T. F. 1998. Studies on the alternation of generations in Cordyceps sinensis. ChungKuoYaoTsaChil. 23(4): 210-212
  16. Litchfield, J. H. 1967. Morel mushroom mycelium as a food flavoring material. Biotechnology Bioengineering 9: 289-304 https://doi.org/10.1002/bit.260090303
  17. Manabe, N., Sugimoto, M., Azuma, Y., Taketomo, N., Yamashita, A., Tsuboi, H., Tsunoo, A., Kinjo, N., Nian-Lai, H. and Miyamoto, H. 1996. Effect of the mycelial extract of cultured Cordyceps sinensis on in vivo hepatic energy metabolism in the mouse. Jpn. J. Pharmacol. 70(1): 85-88 https://doi.org/10.1254/jjp.70.85
  18. Ooi, V. E. C. and Liu, F. 1999. A review of pharmacological activity of mushroom polysaccharides. International Journal of Medicinal Mushrooms 1(3), 195-206 https://doi.org/10.1615/IntJMedMushrooms.v1.i3.10
  19. Shim, J. S., Min, E. G., Chang, H. R., Lee, C. Y., Kim, S. S. and Han, Y. H. 2000. Cytoctxicity against human cancer cell lines by Paecilomyces tenuipes DGUM 32001. Kor. J. Microbial. 36: 312-315
  20. Spatafora, J. W. and Blackwell, M. 1993. Molecular systematics of unitunicate perithecia ascomycetes; the Clavicipitales-Hypocreales connection. Mycologia 85: 912-922 https://doi.org/10.2307/3760674
  21. Wang, S. M., Lee, L. J., Lin, W. W. and Chang, C. M. 1998. Effect of a water-soluble extract of Cordyceps sinensis on steroidogenesis and capsular morphology of lipid droplet in cultured rat adrenocortical cell. J. Cell. Biochem. 69(4): 483-489 https://doi.org/10.1002/(SICI)1097-4644(19980615)69:4<483::AID-JCB9>3.0.CO;2-J
  22. Wu, C. S., Leu, S. F., Yang, H. Y. and Huang, B. M. 2001 Melatonin inhibits the expression of steroidogenic acute regulatory protein and steroidogenesis in MA-10 cells. J. Androl. 22(5): 245-254
  23. Zhu, J. S., Halpern, G. M. and Jones, K. 1998a. The Scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J. Altern. Complement. Med. 4(3): 289-303 https://doi.org/10.1089/acm.1998.4.3-289
  24. Zhu, J. S., Halpern, G. M. and Jones, K. 1998b. The Scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J. Altern. Complement. Med. 4(4): 429-457 https://doi.org/10.1089/acm.1998.4.429

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