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비글견에서 앞쪽목신경절 차단술이 정상 안압에 미치는 영향

The Influence of Cranial Cervical Ganglion Block in Beagle Dogs with Normal Intraocular Pressure

  • 박우대 (서정대학 애완동물학과) ;
  • 배춘식 (전남대학교 수의과대학 및 생물공학연구소) ;
  • 김휘율 (건국대학교 수의과대학)
  • Park, Woo-Dae (Department of Veterinary Nurse and Pet Science, Seojeong College) ;
  • Bae, Chun-Sik (College of Veterinary Medicine, Biotechnology Research Institute, Chonnam National University) ;
  • Kim, Hwi-Yool (College of Veterinary Medicine, Konkuk University)
  • 발행 : 2007.11.30

초록

본 연구는 정상적인 안압을 가진 비글견에서 4가지의 다른 농도를 가진 lidocaine을 사용하여 앞쪽목신경절차단 후 안압의 변화를 관찰하기 위하여 시행하였다. 실험군은 전향적 교차시험으로 10두의 비글견을 2%, 1%, 0.5% 및 0.25% lidocaine group으로 4군으로 나뉘었다. 모든 실험견들은 4 가지의 다른 농도를 가진 2 ml의 lidocaine을 사용하여 각 4번의 앞쪽목신경절 차단을 받았으며 신경 차단은 무작위로 1주일 간격으로 각각 시행되었다. 실험결과 호르너 증후군은 모든 실험군에서 관찰되었다. 1% lidocaine group에서는 대조군과 비교하여 차단 후 5분에서 안압의 유의한 상승이 있었으며(p<0.05), 2%와 1% lidocaine group의 안압은 앞쪽목신경절 차단 후 25분과 45분 사이 감소하였으나, 0.5%와 0.25% lidocaine group은 변화가 없었다. 이상의 결과를 종합하면, 앞쪽 목신경절 차단술은 정상 안압의 변화에 영향을 미치며 0.5%와 0.25% lidocaine은 안압을 변화시키기에는 부적당한 농도로 사료된다.

This study was performed to observe changes of the intraocular pressure following cranial cervical ganglion block with the four different concentrations of lidocaine in beagle dogs with the normal intraocular pressure. We performed by the crossover test in ten beagle dogs divided into four groups, which were 2%, 1%, 0.5% and 0.25% lidocaine group. All experimental dogs received each four times cranial cervical ganglion block using 2 ml of lidocaine with the four different concentrations. The blocks were separately done at a week intervals in random order. Horner#s syndrome was observed in all groups. The intraocular pressure in the blocked side was significantly increased to 5 min in the 1% lidocaine group compared to the baseline (p<0.05). The intraocular pressure of 2% and 1% lidocaine groups were decreased between 25 and 45 min following cranial cervical ganglion block, while those of 0.5% and 0.25% lidocaine groups were unchanged. In conclusion, these results suggest that cranial cervical ganglion block affect on the change of intraocular pressure and 0.5% and 0.25% lidocaine are inadequate concentrations for the change of intraocular pressure in the dog with normal intraocular pressure.

키워드

참고문헌

  1. Bill, A. 1962. Autonomic nervous control of uveal blood flow. Acta. Physiol. Scand. 56, 70-81.
  2. Cho, M. K., S. R. Bai and K. J. Yoon. 1994. The effect of stellate ganglion block on retinal vessel occlusion. J. Korean Ophthalmol. Soc. 35, 1627-1634.
  3. Endo, Y. 1966. Fluctuation of intraocular pressure by blockage of stellar ganglion. Acta. Soc. Ophthalmol. Jpn. 70, 926-933.
  4. Fines, B. S., M. Yanoff and R. A. Stone. 1981. A clinicopathologic study of four cases of primary open angle glaucoma compared to normal eye. Am. J. Ophthalmol. 9, 88-105.
  5. Gang, Y. J. and J. H. Suh. 1994. Chemical Neurolytic Block with Absolute Ethyl Alcohol on Cervical Sympathetic Ganglion in Rabbits. J. Kor. Pain Soc. 7, 162-169.
  6. Haerer, A. F. 1992. Dejong's the neurologic examination. pp. 131-132, 5th eds., JB Lippincott, Philadelphia.
  7. Jonnesco, T. 1899. Resection des halssymathicus in ther behandlung des glaukoms. Wien Klin. Wochenschr. 12, 483-488.
  8. Kim, H. J., S. C. Lee and S. H. Do. 1995. Horner's Syndrome after Epidural Anesthesia. Kor. J. Anestheisol. 29, 569-572. https://doi.org/10.4097/kjae.1995.29.4.569
  9. Kirk, N. G. 1991. Veterinary ophthalmology. pp. 137-138, 239, 733, 2nd eds., Lea & Febiger, Philadelphia.
  10. Linkz, A. 1931. Der einfluss der sympathicusaachaltung auf die blut-kammerwasser schranke. Klin. Wochenschr. 10, 830-837. https://doi.org/10.1007/BF01749523
  11. Machura, M. and Y. Mitaku. 1982. The effect of cervical sympathectomy on the change of electroretinogram by ocular hypertonia in rabbits. Jpn. Ophthalmol. Soc. 86, 307-314.
  12. Miller, S. J. H. 1953. Stellate ganglion block in glaucoma. Br. J. Ophthalmol. 37, 70-76. https://doi.org/10.1136/bjo.37.2.70
  13. Park, C. M., J. B. Kim and H. J. Kil. 1997. The Effects of Superior Cervical Ganglion Block on the Behavioral Despair in Rats. Kor. J. Anesthesiol. 32, 13-18. https://doi.org/10.4097/kjae.1997.32.1.13
  14. Roh, S. J., Y. S. Cheon, B. W. Min, J. S. Goh, H. C. Kim and K. S. Kim. 1991. The Changes of Intraocular Pressure by Stellate Ganglion Block in Glaucoma Patients. J. Kor. Pain Soc. 4, 133-136.
  15. Song, S. O. and Y. H. Suh. 2001. Changes of Plasma Lidocaine Concentrations after Stellate Ganglion Block according to Volume-changes of 1% Lidocaine. J. Kor. Pain Soc. 14, 26-31.
  16. Wagner, H. P. 1931. Cervical sympathectomy in glaucoma. Surg. Clin. N. Am. 11, 867-875.
  17. Wakusugi, B. 1991. New Application of Stellate Ganglion Block. J. Kor. Pain Soc. 4, 1-7.
  18. Wright, S. 1952. Applied physiology. pp. 318, 9th eds., Oxford University Press, London.