Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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The Effect of 12 Weeks Combind Exercise on C-reactive protein, Adiponectin and Insulin Resistance in Obese Middle School Girls

복합운동이 비만 여중생의 인슐린저항성 지표와 C-반응단백, 아디포넥틴에 미치는 효과

  • Jeon, Jae-Young (Department of Physical Education, Pusan National University) ;
  • Kwak, Yi-Sub (Department of Leisure and sport Science, Dong-Eui University)
  • 전재영 (부산대학교 체육교육과) ;
  • 곽이섭 (동의대학교 레저스포츠학과)
  • Published : 2007.10.30
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Abstract

The purpose of the present investigation was to determine the effect of combine exercise on C-reactive protein(CRP) and adiponectin, and to asses whether combine exercise-induced changes in insulin resistance could be explained in part by changes in these in these inflammation markers. Twenty two participants (BMI >95 percentile for age and sex) were allocated exercise group(n=12) and control group(n=10). Subjects had their body shape, body composition, glucose. insulin, HOMA-IR, CPR and adiponectin levels measured. Modest improvements in body composition, insulin resistance markers were observed, however, adiponectin and CRP did not changes. These data suggest that adiponectin and CRP is not a contributory factor to the exercise-relateted improvements in insulin resistance. Additional studies are needed to assess the effects of different duration, modes and intensities of exercise on inflammation markers.

비만 여자 중학생을 대상으로 12주간 12주간 유산소운동과 저항운동을 병행한 복합운동 프로그램을 실시한 결과는 다음과 같다. 본 연구에서 체중감소와 체지방의 감소에 따른 CRP와 아디포넥틴 농도의 개선을 기대하였지만 유의한 변화가 없었다. 본 연구에서는 다음과 같은 결론을 내린다. 1. 12주간의 중강도 운동 프로그램은 혈장 CRP와 혈장 아디포넥틴의 유용한 개선에 영향을 미치지 않는다. 2. 운동에 의한 인슐린저항성은 이러한 특별한 혈장 염증 지표들의 농도 변화에 의해 설명되어지지 않는다. 이상으로 본 연구에서 처방된 운동프로그램은 신체조성과 인슐린저항성의 변화에는 긍정적인 영향을 미쳤지만 이러한 인자의 개선에도 불구하고 CRP와 아디포넥틴 농도의 변화에는 영향을 미치지 못하였다. 따라서 앞으로 16주 이상의 운동기간과 운동강도에 따른 복합운동 프로그램의 실시가 CRP와 아디포넥틴의 변화에 미치는 영향과 CRP의 발현에 관련인자인 $TNF-{\alpha}$, IL-6 등과 같은 인자들의 변화에 미치는 추가적인 연구가 필요하다.

Keywords

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