Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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Radiographic Evaluation of Limb Bone Development in Miniature Porcine

미니돼지의 팔다리 뼈 성장에 대한 방사선학적 평가

  • Chang, Jin-Hwa (Department of Veterinary Radiology, College of Veterinary Medicine Seoul National University) ;
  • Jung, Joo-Hyun (Department of Veterinary Radiology, College of Veterinary Medicine Seoul National University) ;
  • Choi, Min-Cheol (Department of Veterinary Radiology, College of Veterinary Medicine Seoul National University)
  • 장진화 (서울대학교 수의과대학 수의방사선학과) ;
  • 정주현 (서울대학교 수의과대학 수의방사선학과) ;
  • 최민철 (서울대학교 수의과대학 수의방사선학과)
  • Published : 2007.10.30
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Abstract

Epiphyseal development in the long bones was studied radiographically in minipigs. Radiographs of the proximal and distal epiphyses of humerus, radius, ulna, femur and tibia were obtained at 4, 8, 12, 20, 40, 48, 96 and 144 weeks of age in total 58 minipigs. The assessment of maturity process was made in accordance with the criteria proposed by Owada and Sutow. The secondary ossification centers developed rapidly from 4 weeks of age to 40 weeks of age, and gradually thereafter until 96 weeks of age. The earliest epiphyseal fusion was apparent in the proximal radius, proximal and distal femur at 96 weeks of age. The complete fusion of the epiphyseal line in the long bones was evident on 144 weeks of age and was observed in most long bones such as the proximal humerus, the proximal and distal ulna and the distal radius, and the proximal tibia in minipigs.

미니돼지의 긴 뼈의 뼈끝(epiphysis) 성장에 대한 연구를 위해 상완골, 요골, 척골, 대퇴골, 경골의 근위 및 원위 뼈끝 부위를 중심으로 방사선 촬영을 실시하였다. 실험에 이용된 미니돼지의 연령대는 4주, 8주, 12주, 20주, 40주, 48주, 96주, 144주령으로 총 58마리였다. 뼈 성장과정에 대한 평가는 Owada & Sutow가 제안한 11가지 기준을 토대로 하였다. 긴 뼈에서 이차뼈발생중심은 4주령에서 40주령까지 빠른 성장을 보였고, 그 이후 96주령까지는 초기보다 느린 성장을 보였다. 가장 빠른 뼈끝 유합시기는 96주령으로 근위 요골, 근위 및 원위 대퇴골에서 관찰되었다. 미니돼지의 일반적인 긴 뼈의 완전한 뼈끝 유합은 144주령에 나타났으며 근위 상완골, 근위 및 원위 척골, 원위 요골, 그리고 근위 경골에서 관찰되었다.

Keywords

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